Ttc4 (tetratricopeptide repeat domain 4) - Rat Genome Database

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Gene: Ttc4 (tetratricopeptide repeat domain 4) Chinchilla lanigera
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Symbol: Ttc4
Name: tetratricopeptide repeat domain 4
RGD ID: 8711762
Description: INVOLVED IN defense response to virus (ortholog); innate immune response (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tetratricopeptide repeat protein 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554644,629,932 - 4,669,333 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554644,629,061 - 4,669,054 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ttc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554644,629,932 - 4,669,333 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554644,629,061 - 4,669,054 (-)NCBIChiLan1.0ChiLan1.0
TTC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38154,715,861 - 54,742,657 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl154,715,861 - 54,742,657 (+)EnsemblGRCh38hg38GRCh38
GRCh37155,181,534 - 55,208,330 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36154,954,117 - 54,980,569 (+)NCBINCBI36Build 36hg18NCBI36
Build 34154,893,576 - 54,920,001NCBI
Celera153,469,087 - 53,495,920 (+)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef153,295,157 - 53,322,784 (+)NCBIHuRef
CHM1_1155,296,858 - 55,323,691 (+)NCBICHM1_1
T2T-CHM13v2.0154,596,115 - 54,622,890 (+)NCBIT2T-CHM13v2.0
Ttc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394106,514,952 - 106,536,188 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4106,519,453 - 106,536,141 (-)EnsemblGRCm39 Ensembl
GRCm384106,656,806 - 106,679,002 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4106,662,256 - 106,678,944 (-)EnsemblGRCm38mm10GRCm38
MGSCv374106,334,413 - 106,351,549 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364106,160,188 - 106,176,814 (-)NCBIMGSCv36mm8
Celera4105,024,628 - 105,041,763 (-)NCBICelera
Cytogenetic Map4C7NCBI
cM Map449.68NCBI
Ttc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85126,673,535 - 126,691,203 (-)NCBIGRCr8
mRatBN7.25121,444,712 - 121,462,381 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5121,445,740 - 121,462,287 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5124,063,423 - 124,081,060 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05125,786,475 - 125,804,112 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05125,837,736 - 125,855,373 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05126,264,758 - 126,282,431 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5126,264,105 - 126,282,385 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05130,109,141 - 130,127,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45127,746,728 - 127,756,081 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15127,751,976 - 127,761,307 (-)NCBI
Celera5120,201,186 - 120,210,532 (-)NCBICelera
Cytogenetic Map5q34NCBI
TTC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21172,092,298 - 172,118,317 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11171,233,183 - 171,259,181 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0153,992,074 - 54,018,030 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1155,581,396 - 55,607,646 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl155,581,396 - 55,607,646 (+)Ensemblpanpan1.1panPan2
TTC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1554,406,216 - 54,431,742 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl554,407,287 - 54,431,687 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha554,475,489 - 54,500,962 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0554,594,550 - 54,619,793 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl554,590,047 - 54,619,822 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1554,590,989 - 54,616,219 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0554,481,088 - 54,506,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0554,870,103 - 54,895,370 (-)NCBIUU_Cfam_GSD_1.0
Ttc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505868,857,176 - 68,884,945 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365226,529,122 - 6,559,292 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365226,525,887 - 6,559,147 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6157,616,502 - 157,651,655 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16157,616,499 - 157,651,676 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26145,680,005 - 145,715,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12078,193,416 - 78,222,430 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2078,190,147 - 78,222,349 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603339,060,341 - 39,088,741 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248625,097,343 - 5,126,537 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248625,097,233 - 5,126,555 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000025443   ⟹   ENSCLAP00000025197
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554644,629,932 - 4,669,333 (-)Ensembl
RefSeq Acc Id: XM_005398518   ⟹   XP_005398575
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554644,629,061 - 4,669,053 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005398519   ⟹   XP_005398576
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554644,629,061 - 4,668,961 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001236700
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554644,631,960 - 4,669,054 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005398575 (Get FASTA)   NCBI Sequence Viewer  
  XP_005398576 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025197
  ENSCLAP00000025197.1
RefSeq Acc Id: XP_005398575   ⟸   XM_005398518
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W4V3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005398576   ⟸   XM_005398519
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSCLAP00000025197   ⟸   ENSCLAT00000025443
Protein Domains
Cns1/TTC4 wheel


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000017302 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000025443 ENTREZGENE
  ENSCLAT00000025443.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro Csn1/TTC4_wheel UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene Ttc4 ENTREZGENE
PANTHER TETRATRICOPEPTIDE REPEAT PROTEIN 4 UniProtKB/TrEMBL
  TETRATRICOPEPTIDE REPEAT PROTEIN 4 UniProtKB/TrEMBL
Pfam Wheel UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A8C2W4V3 ENTREZGENE, UniProtKB/TrEMBL