PPY (pancreatic polypeptide) - Rat Genome Database

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Gene: PPY (pancreatic polypeptide) Homo sapiens
Analyze
Symbol: PPY
Name: pancreatic polypeptide
RGD ID: 737129
HGNC Page HGNC:9327
Description: Enables G protein-coupled receptor binding activity. Predicted to be involved in feeding behavior and neuropeptide signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: pancreatic polypeptide prohormone; pancreatic polypeptide Y; pancreatic prohormone; PH; PNP; PP; prepro-PP (prepropancreatic polypeptide)
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: PPY2P  
Allele / Splice: See ClinVar data
Candidate Gene For: BW444_H BW453_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381743,940,804 - 43,944,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1743,940,804 - 43,942,476 (-)EnsemblGRCh38hg38GRCh38
GRCh371742,018,172 - 42,019,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361739,373,698 - 39,375,359 (-)NCBINCBI36Build 36hg18NCBI36
Build 341739,373,698 - 39,374,548NCBI
Celera1738,726,213 - 38,727,874 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1737,782,442 - 37,784,103 (-)NCBIHuRef
CHM1_11742,253,758 - 42,255,419 (-)NCBICHM1_1
T2T-CHM13v2.01744,793,351 - 44,796,763 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:782992   PMID:1194289   PMID:2997153   PMID:3753985   PMID:6094571   PMID:6138294   PMID:6366786   PMID:6373251   PMID:7014602   PMID:7031480   PMID:7493937   PMID:7592911  
PMID:8244379   PMID:11825640   PMID:11825647   PMID:11825648   PMID:12187924   PMID:12477932   PMID:14988250   PMID:15489334   PMID:15561938   PMID:15966750   PMID:15998659   PMID:15998783  
PMID:16359755   PMID:17171555   PMID:17235527   PMID:17325259   PMID:18577758   PMID:21813805   PMID:21873635   PMID:22020285   PMID:22399387   PMID:22673566   PMID:22979996   PMID:23371976  
PMID:23956349   PMID:24375409   PMID:25445712   PMID:25990478   PMID:26002416   PMID:26766123   PMID:27918953   PMID:28027898   PMID:29771765   PMID:32296183   PMID:33918032   PMID:33961781  
PMID:34294685  


Genomics

Comparative Map Data
PPY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381743,940,804 - 43,944,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1743,940,804 - 43,942,476 (-)EnsemblGRCh38hg38GRCh38
GRCh371742,018,172 - 42,019,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361739,373,698 - 39,375,359 (-)NCBINCBI36Build 36hg18NCBI36
Build 341739,373,698 - 39,374,548NCBI
Celera1738,726,213 - 38,727,874 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1737,782,442 - 37,784,103 (-)NCBIHuRef
CHM1_11742,253,758 - 42,255,419 (-)NCBICHM1_1
T2T-CHM13v2.01744,793,351 - 44,796,763 (-)NCBIT2T-CHM13v2.0
Ppy
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,990,757 - 101,992,145 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,990,756 - 101,992,145 (-)EnsemblGRCm39 Ensembl
GRCm3811102,099,931 - 102,101,319 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11102,099,930 - 102,101,319 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,961,245 - 101,962,614 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,916,021 - 101,917,390 (-)NCBIMGSCv36mm8
Celera11113,805,823 - 113,807,218 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1165.48NCBI
Ppy
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81087,554,941 - 87,556,236 (-)NCBIGRCr8
mRatBN7.21087,054,747 - 87,056,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1087,054,756 - 87,055,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1092,084,611 - 92,085,906 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01091,556,506 - 91,557,781 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,949,824 - 86,951,097 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01090,041,582 - 90,043,316 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1090,041,591 - 90,042,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,831,063 - 89,832,358 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41091,167,958 - 91,169,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11091,182,327 - 91,183,623 (-)NCBI
Celera1085,772,353 - 85,773,648 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Ppy
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,155,876 - 17,156,214 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,155,681 - 17,156,829 (-)NCBIChiLan1.0ChiLan1.0
PPY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21920,963,508 - 20,965,182 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11722,927,788 - 22,929,460 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01713,452,839 - 13,454,513 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11713,619,132 - 13,620,788 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1713,619,936 - 13,620,788 (+)Ensemblpanpan1.1panPan2
PPY
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1919,394,185 - 19,395,750 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl919,394,183 - 19,395,750 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha918,784,564 - 18,785,316 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,089,261 - 20,090,853 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl920,090,101 - 20,090,853 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1918,943,380 - 18,944,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,126,341 - 19,127,093 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,271,259 - 19,272,011 (+)NCBIUU_Cfam_GSD_1.0
Ppy
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560218,730,726 - 18,731,524 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936541463,068 - 464,542 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936541463,069 - 463,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,217,806 - 19,218,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11219,217,649 - 19,218,680 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21219,451,675 - 19,455,138 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPY
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11662,450,284 - 62,453,995 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1662,453,141 - 62,453,871 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607733,225,253 - 33,228,638 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppy
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624795908,495 - 909,435 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PPY
7 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2		 pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3		 pathogenic
GRCh38/hg38 17q12-21.31(chr17:39199873-45629579)x3 copy number gain See cases [RCV000052479] Chr17:39199873..45629579 [GRCh38]
Chr17:37356126..43706945 [GRCh37]
Chr17:34609652..41062728 [NCBI36]
Chr17:17q12-21.31		 pathogenic
GRCh38/hg38 17q21.31(chr17:43570878-44762377)x1 copy number loss See cases [RCV000053429] Chr17:43570878..44762377 [GRCh38]
Chr17:41648246..42839745 [GRCh37]
Chr17:39003772..40195271 [NCBI36]
Chr17:17q21.31		 pathogenic
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1		 pathogenic
GRCh38/hg38 17q21.31(chr17:43934167-44854025)x1 copy number loss See cases [RCV000134949] Chr17:43934167..44854025 [GRCh38]
Chr17:42011535..42931393 [GRCh37]
Chr17:39367061..40286919 [NCBI36]
Chr17:17q21.31		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
NM_002722.5(PPY):c.49G>A (p.Val17Met) single nucleotide variant not specified [RCV004298711] Chr17:43941606 [GRCh38]
Chr17:42018974 [GRCh37]
Chr17:17q21.31		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q21.31(chr17:41540257-42044249)x1 copy number loss not provided [RCV000683936] Chr17:41540257..42044249 [GRCh37]
Chr17:17q21.31		 uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q21.31(chr17:41399892-42125780)x3 copy number gain not provided [RCV001006903] Chr17:41399892..42125780 [GRCh37]
Chr17:17q21.31		 uncertain significance
NM_002722.5(PPY):c.14G>A (p.Arg5His) single nucleotide variant not specified [RCV004238993] Chr17:43941641 [GRCh38]
Chr17:42019009 [GRCh37]
Chr17:17q21.31		 uncertain significance
NM_002722.5(PPY):c.230C>T (p.Ser77Leu) single nucleotide variant not specified [RCV004219766] Chr17:43941176 [GRCh38]
Chr17:42018544 [GRCh37]
Chr17:17q21.31		 likely benign
NM_002722.5(PPY):c.127C>T (p.Pro43Ser) single nucleotide variant not specified [RCV004102738] Chr17:43941528 [GRCh38]
Chr17:42018896 [GRCh37]
Chr17:17q21.31		 uncertain significance
NM_002722.5(PPY):c.185G>T (p.Arg62Met) single nucleotide variant not specified [RCV004303388] Chr17:43941470 [GRCh38]
Chr17:42018838 [GRCh37]
Chr17:17q21.31		 uncertain significance
GRCh38/hg38 17q21.31(chr17:43603558-44033313) copy number gain Anomalous pulmonary venous return [RCV003223581] Chr17:43603558..44033313 [GRCh38]
Chr17:17q21.31		 uncertain significance
NM_002722.5(PPY):c.209A>T (p.Lys70Ile) single nucleotide variant not specified [RCV004510295] Chr17:43941197 [GRCh38]
Chr17:42018565 [GRCh37]
Chr17:17q21.31		 uncertain significance
NM_002722.5(PPY):c.193T>A (p.Tyr65Asn) single nucleotide variant not specified [RCV004510294] Chr17:43941213 [GRCh38]
Chr17:42018581 [GRCh37]
Chr17:17q21.31		 uncertain significance
GRCh37/hg19 17q12-22(chr17:41196270-41277589) copy number loss Breast-ovarian cancer, familial, susceptibility to, 1 [RCV004759419] Chr17:41196270..41277589 [GRCh37]
Chr17:17q12-22		 pathogenic
Single allele deletion Breast-ovarian cancer, familial, susceptibility to, 1 [RCV004759420] Chr17:41231503..41277589 [GRCh37]
Chr17:17q21.31-22		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2007
Count of miRNA genes:590
Interacting mature miRNAs:690
Transcripts:ENST00000225992, ENST00000587006, ENST00000587070, ENST00000587926, ENST00000591228, ENST00000591703
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH80047  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371742,018,180 - 42,018,570UniSTSGRCh37
GRCh371726,574,918 - 26,575,306UniSTSGRCh37
Build 361723,599,045 - 23,599,433RGDNCBI36
Celera1738,726,221 - 38,726,611UniSTS
Celera1723,436,651 - 23,437,039RGD
Cytogenetic Map17q11UniSTS
Cytogenetic Map17q21UniSTS
HuRef1737,782,450 - 37,782,840UniSTS
HuRef1722,782,949 - 22,783,337UniSTS
GDB:178570  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371742,018,101 - 42,018,351UniSTSGRCh37
Build 361739,373,627 - 39,373,877RGDNCBI36
Celera1738,726,142 - 38,726,392RGD
Cytogenetic Map17q21UniSTS
HuRef1737,782,371 - 37,782,621UniSTS
RH71368  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371742,018,031 - 42,018,156UniSTSGRCh37
Build 361739,373,557 - 39,373,682RGDNCBI36
Celera1738,726,072 - 38,726,197RGD
Cytogenetic Map17q21UniSTS
HuRef1737,782,301 - 37,782,426UniSTS
GeneMap99-GB4 RH Map17322.36UniSTS
GDB:180950  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371742,018,272 - 42,018,970UniSTSGRCh37
Celera1738,726,313 - 38,727,011UniSTS
Cytogenetic Map17q21UniSTS
HuRef1737,782,542 - 37,783,240UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
223 775 540 322 1453 751 811 2 94 599 72 791 1562 1348 12 802 166 688 697 26

Sequence


Ensembl Acc Id: ENST00000225992   ⟹   ENSP00000225992
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,804 - 43,942,476 (-)Ensembl
Ensembl Acc Id: ENST00000587006   ⟹   ENSP00000465711
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,815 - 43,941,654 (-)Ensembl
Ensembl Acc Id: ENST00000587070   ⟹   ENSP00000489472
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,804 - 43,941,514 (-)Ensembl
Ensembl Acc Id: ENST00000587926
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,804 - 43,941,299 (-)Ensembl
Ensembl Acc Id: ENST00000591228   ⟹   ENSP00000466009
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,805 - 43,942,274 (-)Ensembl
Ensembl Acc Id: ENST00000591703   ⟹   ENSP00000466546
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1743,940,804 - 43,942,465 (-)Ensembl
RefSeq Acc Id: NM_001319209   ⟹   NP_001306138
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381743,940,804 - 43,942,274 (-)NCBI
CHM1_11742,253,756 - 42,255,228 (-)NCBI
T2T-CHM13v2.01744,793,351 - 44,794,821 (-)NCBI
Sequence:
RefSeq Acc Id: NM_002722   ⟹   NP_002713
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381743,940,804 - 43,942,476 (-)NCBI
GRCh371742,018,172 - 42,019,833 (-)ENTREZGENE
Build 361739,373,698 - 39,375,359 (-)NCBI Archive
HuRef1737,782,442 - 37,784,103 (-)ENTREZGENE
CHM1_11742,253,756 - 42,255,421 (-)NCBI
T2T-CHM13v2.01744,793,351 - 44,795,023 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524978   ⟹   XP_011523280
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381743,940,804 - 43,944,215 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054316627   ⟹   XP_054172602
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01744,793,351 - 44,796,763 (-)NCBI
RefSeq Acc Id: NP_002713   ⟸   NM_002722
- Peptide Label: isoform 1 preproprotein
- UniProtKB: P01298 (UniProtKB/Swiss-Prot),   K7EKP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011523280   ⟸   XM_011524978
- Peptide Label: isoform X1
- UniProtKB: K7EKP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001306138   ⟸   NM_001319209
- Peptide Label: isoform 2 precursor
- UniProtKB: K7EKP2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000465711   ⟸   ENST00000587006
Ensembl Acc Id: ENSP00000489472   ⟸   ENST00000587070
Ensembl Acc Id: ENSP00000466546   ⟸   ENST00000591703
Ensembl Acc Id: ENSP00000466009   ⟸   ENST00000591228
Ensembl Acc Id: ENSP00000225992   ⟸   ENST00000225992
RefSeq Acc Id: XP_054172602   ⟸   XM_054316627
- Peptide Label: isoform X1
- UniProtKB: K7EKP2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P01298-F1-model_v2 AlphaFold P01298 1-95 view protein structure

Promoters
RGD ID:7235211
Promoter ID:EPDNEW_H23351
Type:multiple initiation site
Name:PPY_1
Description:pancreatic polypeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23352  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381743,942,476 - 43,942,536EPDNEW
RGD ID:7235213
Promoter ID:EPDNEW_H23352
Type:initiation region
Name:PPY_2
Description:pancreatic polypeptide
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H23351  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381743,944,071 - 43,944,131EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9327 AgrOrtholog
COSMIC PPY COSMIC
Ensembl Genes ENSG00000108849 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000225992 ENTREZGENE
  ENST00000225992.8 UniProtKB/Swiss-Prot
  ENST00000587006.2 UniProtKB/TrEMBL
  ENST00000587070.5 UniProtKB/TrEMBL
  ENST00000591228.4 UniProtKB/Swiss-Prot
  ENST00000591703.5 UniProtKB/TrEMBL
Gene3D-CATH 6.10.250.900 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000108849 GTEx
HGNC ID HGNC:9327 ENTREZGENE
Human Proteome Map PPY Human Proteome Map
InterPro Pancreatic_hormone-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pancreatic_hormone-like_CS UniProtKB/Swiss-Prot
KEGG Report hsa:5539 UniProtKB/Swiss-Prot
NCBI Gene 5539 ENTREZGENE
OMIM 167780 OMIM
PANTHER PTHR10533 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10533:SF2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hormone_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33690 PharmGKB
PRINTS PANCHORMONE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PANCREATIC_HORMONE_1 UniProtKB/Swiss-Prot
  PANCREATIC_HORMONE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PAH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RRD5_HUMAN UniProtKB/TrEMBL
  K7EKP2 ENTREZGENE, UniProtKB/TrEMBL
  K7EML0_HUMAN UniProtKB/TrEMBL
  P01298 ENTREZGENE, UniProtKB/Swiss-Prot