TMLHE-AS1 (TMLHE antisense RNA 1) - Rat Genome Database

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Gene: TMLHE-AS1 (TMLHE antisense RNA 1) Homo sapiens
Analyze
Symbol: TMLHE-AS1
Name: TMLHE antisense RNA 1
RGD ID: 6893191
HGNC Page HGNC:44261
Description: ASSOCIATED WITH Autism; autistic disorder; Decreased circulating antibody concentration; INTERACTS WITH sodium arsenite
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: RP11-954J6.3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X155,466,540 - 155,494,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX155,457,738 - 155,611,616 (+)EnsemblGRCh38hg38GRCh38
GRCh37X154,696,201 - 154,723,771 (+)NCBIGRCh37GRCh37hg19GRCh37
CeleraX154,761,529 - 154,763,221 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX143,146,873 - 143,148,567 (-)NCBIHuRef
CHM1_1X154,578,312 - 154,635,401 (+)NCBICHM1_1
T2T-CHM13v2.0X153,704,542 - 153,732,358 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMLHE-AS1Humanautistic disorder  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Epsilon-trimethyllysine hydroxylase deficiencyClinVarPMID:23092983
TMLHE-AS1Humanautistic disorder  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
TMLHE-AS1Humanimmunodeficiency 33  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 33ClinVarPMID:25741868
TMLHE-AS1HumanSplenomegaly  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: SplenomegalyClinVarPMID:25741868


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMLHE-AS1Humansodium arsenite increases expressionEXP 6480464sodium arsenite results in increased expression of TMLHE-AS1 mRNACTDPMID:29301061

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
TMLHE-AS1HumanAutism  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
TMLHE-AS1HumanDecreased circulating antibody concentration  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Decreased antibody level in bloodClinVarPMID:25741868
TMLHE-AS1HumanSplenomegaly  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: SplenomegalyClinVarPMID:25741868

#
Reference Title
Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations


.

.
Variants in TMLHE-AS1
7 total Variants

1 to 10 of 120 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
GRCh38/hg38 Xp22.33-q28(chrX:10701-155978689)x1 copy number loss See cases [RCV000133792] ChrX:10701..155978689 [GRCh38]
ChrX:60701..155208354 [GRCh37]
ChrX:701..154861548 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xq27.1-28(chrX:139333024-155978689)x1 copy number loss See cases [RCV000133818] ChrX:139333024..155978689 [GRCh38]
ChrX:138415183..155208354 [GRCh37]
ChrX:138242849..154861548 [NCBI36]
ChrX:Xq27.1-28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156013167)x1 copy number loss See cases [RCV000050386] ChrX:10679..156013167 [GRCh38]
ChrX:60679..155242832 [GRCh37]
ChrX:679..154896026 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156013167)x3 copy number gain See cases [RCV000050385] ChrX:10679..156013167 [GRCh38]
ChrX:60679..155242832 [GRCh37]
ChrX:679..154896026 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:14245-155999293)x1 copy number loss See cases [RCV000052982] ChrX:14245..155999293 [GRCh38]
ChrX:64245..155228958 [GRCh37]
ChrX:4245..154882152 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:26102-155996431)x1 copy number loss See cases [RCV000052986] ChrX:26102..155996431 [GRCh38]
ChrX:76102..155226096 [GRCh37]
ChrX:16102..154879290 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:26102-155996431)x3 copy number gain See cases [RCV000052984] ChrX:26102..155996431 [GRCh38]
ChrX:76102..155226096 [GRCh37]
ChrX:16102..154879290 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xq21.1-28(chrX:85123740-156022206)x3 copy number gain See cases [RCV000133744] ChrX:85123740..156022206 [GRCh38]
ChrX:84378746..155251871 [GRCh37]
ChrX:84265402..154905065 [NCBI36]
ChrX:Xq21.1-28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:10679-156022826)x4 copy number gain See cases [RCV000133654] ChrX:10679..156022826 [GRCh38]
ChrX:60679..155252491 [GRCh37]
ChrX:679..154905685 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
GRCh38/hg38 Xp22.33-q28(chrX:20297-155999253)x3 copy number gain See cases [RCV000134564] ChrX:20297..155999253 [GRCh38]
ChrX:70297..155228918 [GRCh37]
ChrX:10297..154882112 [NCBI36]
ChrX:Xp22.33-q28		 pathogenic
1 to 10 of 120 rows

Predicted Target Of
Summary Value
Count of predictions:224
Count of miRNA genes:215
Interacting mature miRNAs:219
Transcripts:ENST00000433624, ENST00000452506, ENST00000541151
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

G43495  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X154,697,172 - 154,697,295UniSTSGRCh37
GRCh37X154,602,731 - 154,602,854UniSTSGRCh37
Build 36X154,255,925 - 154,256,048RGDNCBI36
CeleraX154,761,555 - 154,761,678RGD
Cytogenetic MapXq28UniSTS
HuRefX143,146,899 - 143,147,022UniSTS
sWXD2469  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X154,694,800 - 154,695,191UniSTSGRCh37
GRCh37X154,604,833 - 154,605,224UniSTSGRCh37
Build 36X154,258,027 - 154,258,418RGDNCBI36
CeleraX154,763,661 - 154,764,052RGD
Cytogenetic MapXq28UniSTS
HuRefX143,149,007 - 143,149,398UniSTS
AU048852  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37X154,696,858 - 154,697,279UniSTSGRCh37
GRCh37X154,602,747 - 154,603,166UniSTSGRCh37
Build 36X154,255,941 - 154,256,360RGDNCBI36
Celera5132,169,648 - 132,170,182UniSTS
CeleraX154,761,571 - 154,761,990RGD
Cytogenetic MapXq28UniSTS
HuRefX143,146,915 - 143,147,336UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1114 2217 2133 1859 4195 1585 2077 4 518 1570 373 1816 5946 5534 41 3325 778 1624 1451 154



Ensembl Acc Id: ENST00000433624
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,466,540 - 155,494,110 (+)Ensembl
Ensembl Acc Id: ENST00000447347
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,468,286 - 155,487,046 (+)Ensembl
Ensembl Acc Id: ENST00000452506
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,489,323 - 155,611,616 (+)Ensembl
Ensembl Acc Id: ENST00000717381
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,457,784 - 155,511,446 (+)Ensembl
Ensembl Acc Id: ENST00000717382
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,681 - 155,510,197 (+)Ensembl
Ensembl Acc Id: ENST00000833578
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,457,839 - 155,544,565 (+)Ensembl
Ensembl Acc Id: ENST00000833579
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,759 - 155,544,565 (+)Ensembl
Ensembl Acc Id: ENST00000833580
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,457,794 - 155,511,443 (+)Ensembl
Ensembl Acc Id: ENST00000833581
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,698 - 155,511,443 (+)Ensembl
Ensembl Acc Id: ENST00000833582
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,722 - 155,511,446 (+)Ensembl
Ensembl Acc Id: ENST00000833583
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,457,738 - 155,510,208 (+)Ensembl
Ensembl Acc Id: ENST00000833584
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,677 - 155,510,197 (+)Ensembl
Ensembl Acc Id: ENST00000833585
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,713 - 155,510,205 (+)Ensembl
Ensembl Acc Id: ENST00000833586
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,730 - 155,510,208 (+)Ensembl
Ensembl Acc Id: ENST00000833587
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,743 - 155,510,197 (+)Ensembl
Ensembl Acc Id: ENST00000833588
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,779 - 155,510,208 (+)Ensembl
Ensembl Acc Id: ENST00000833589
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,732 - 155,510,114 (+)Ensembl
Ensembl Acc Id: ENST00000833590
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,466,529 - 155,510,197 (+)Ensembl
Ensembl Acc Id: ENST00000833591
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,763 - 155,493,130 (+)Ensembl
Ensembl Acc Id: ENST00000833592
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 EnsemblX155,458,722 - 155,480,490 (+)Ensembl
RefSeq Acc Id: NR_039991
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X155,466,540 - 155,494,110 (+)NCBI
GRCh37X154,696,201 - 154,723,771 (+)NCBI
CHM1_1X154,578,312 - 154,635,401 (+)NCBI
T2T-CHM13v2.0X153,704,542 - 153,732,358 (+)NCBI
Sequence:
GenBank Protein BAC05406 (Get FASTA)   NCBI Sequence Viewer  

RGD ID:15097497
Promoter ID:EPDNEWNC_H2327
Type:initiation region
Name:TMLHE-AS1_1
Description:TMLHE antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:44261]
SO ACC ID:SO:0000170
Source:EPDNEWNC (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38X155,466,521 - 155,466,581EPDNEWNC


1 to 9 of 9 rows
Database
Acc Id
Source(s)
COSMIC TMLHE-AS1 COSMIC
Ensembl Genes ENSG00000224533 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000433624 ENTREZGENE
GTEx ENSG00000224533 GTEx
HGNC ID HGNC:44261 ENTREZGENE
Human Proteome Map TMLHE-AS1 Human Proteome Map
NCBI Gene TMLHE-AS1 ENTREZGENE
RNAcentral URS000001A014 RNACentral
  URS000056D05E RNACentral
1 to 9 of 9 rows