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Gene: Meox1 (mesenchyme homeobox 1) Rattus rattus

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Symbol:

Meox1

Name:

mesenchyme homeobox 1

RGD ID:

626004655

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); sclerotome development (ortholog); somite development (ortholog); ASSOCIATED WITH allergic contact dermatitis (ortholog); cholangiocarcinoma (ortholog); esophageal cancer (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

homeobox protein MOX-1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MEOX1 (mesenchyme homeobox 1)	NCBI	Ortholog
Mus musculus (house mouse):	Meox1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Meox1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Meox1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MEOX1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MEOX1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Meox1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MEOX1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MEOX1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Meox1 (mesenchyme homeobox 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Rrattus_CSIRO_v1 - Rrattus_CSIRO_v1 Assembly

Position:

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	61,163,977 - 61,182,432 (-)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

allergic contact dermatitis (ISO)

cholangiocarcinoma (ISO)

esophageal cancer (ISO)

genetic disease (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Klippel-Feil syndrome (ISO)

Klippel-Feil syndrome 2 (ISO)

lung adenocarcinoma (ISO)

lung non-small cell carcinoma (ISO)

ovarian serous cystadenocarcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of transcription by RNA polymerase II (ISO)

sclerotome development (ISO)

somite development (ISO)

somite specification (ISO)

Cellular Component

cytoplasm (ISO)

nucleus (ISO)

Molecular Function

chromatin binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (ISO)

HMG box domain binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Meox1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	61,163,977 - 61,182,432 (-)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

MEOX1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	43,640,389 - 43,661,922 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	43,640,072 - 43,661,929 (-)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	17	41,717,757 - 41,739,290 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	39,073,283 - 39,094,788 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	39,073,285 - 39,094,457	NCBI
Celera	17	38,425,737 - 38,447,247 (-)	NCBI		Celera
Cytogenetic Map	17	q21.31	NCBI
HuRef	17	37,482,058 - 37,503,546 (-)	NCBI		HuRef
CHM1_1	17	41,953,427 - 41,974,933 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	44,492,923 - 44,514,459 (-)	NCBI		T2T-CHM13v2.0

Meox1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	101,768,336 - 101,785,309 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	101,768,336 - 101,785,227 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	101,877,510 - 101,894,354 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	101,877,510 - 101,894,374 (-)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	11	101,738,824 - 101,755,668 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	101,693,600 - 101,710,444 (-)	NCBI		MGSCv36	mm8
Celera	11	113,579,104 - 113,597,142 (-)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	65.48	NCBI

Meox1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	87,318,668 - 87,338,169 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	87,318,695 - 87,337,976 (-)	Ensembl				GRCr8
mRatBN7.2	10	86,818,450 - 86,837,563 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	86,818,478 - 86,837,660 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	91,847,337 - 91,866,465 (-)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	91,322,912 - 91,342,086 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	86,716,213 - 86,735,389 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	90,461,109 - 90,480,290 (-)	NCBI
Lyon_Normotensive	10	91,192,881 - 91,212,054 (-)	NCBI
Lyon_Hypertensive	10	92,637,964 - 92,657,138 (-)	NCBI
F344_StmMcwi	10	92,745,869 - 92,765,045 (-)	NCBI
Rnor_6.0	10	89,797,011 - 89,817,009 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	89,797,038 - 89,816,491 (-)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	10	89,590,582 - 89,609,632 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	90,921,589 - 90,942,298 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	85,538,517 - 85,557,370 (-)	NCBI		Celera
RGSC_v3.1	10	90,937,064 - 91,032,603 (-)	NCBI
Cytogenetic Map	10	q32.1	NCBI

Meox1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	17,012,982 - 17,022,186 (-)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955451	17,013,180 - 17,022,131 (-)	NCBI	ChiLan1.0	ChiLan1.0

MEOX1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	21,245,821 - 21,267,271 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	23,210,507 - 23,233,067 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	13,733,235 - 13,756,584 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	13,982,668 - 14,003,820 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	13,982,668 - 14,003,820 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

MEOX1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	19,614,568 - 19,641,426 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	19,614,503 - 19,640,908 (+)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	19,008,862 - 19,030,248 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	20,314,935 - 20,336,327 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	20,309,565 - 20,335,856 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	19,167,703 - 19,189,081 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	19,350,611 - 19,371,980 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	19,496,073 - 19,517,460 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Meox1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	3	19,041,304 - 19,061,579 (+)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024405602	18,956,445 - 18,978,036 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936541	217,193 - 236,031 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936541	216,390 - 238,153 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MEOX1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	19,431,420 - 19,451,993 (+)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	12	19,431,397 - 19,452,430 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	19,664,809 - 19,683,972 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MEOX1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	16	68,153,554 - 68,175,665 (+)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666077	33,514,931 - 33,537,124 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	16	62,747,031 - 62,770,711 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	62,748,671 - 62,770,706 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Meox1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624795	1,032,278 - 1,041,635 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624795	1,032,546 - 1,040,007 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	20	20,915,612 - 20,923,713 (-)	Ensembl

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_032914507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAAIVD010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_032914507 ⟹ XP_032770398

Type:

CODING

Position:

Black Rat Assembly	Chr	Position (strand)	Source
Rrattus_CSIRO_v1	9	61,163,977 - 61,182,432 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_032770398	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_032770398 ⟸ XM_032914507

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Meox1	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM