(1->4)-beta-D-glucan multiple interactions ISO RGD:1550273 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SMAD5 mRNA CTD PMID:36331819 1,2-dimethylhydrazine decreases expression ISO RGD:1550273 6480464 1, 2-Dimethylhydrazine results in decreased expression of SMAD5 mRNA CTD PMID:22206623 17beta-estradiol increases expression ISO RGD:1550273 6480464 Estradiol results in increased expression of SMAD5 mRNA CTD PMID:25210133 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1550273 6480464 Tetrachlorodibenzodioxin affects the expression of SMAD5 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1550273 6480464 Tetrachlorodibenzodioxin results in increased expression of SMAD5 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SMAD5 mRNA CTD PMID:19490992 , PMID:33387578 4-hydroxyphenyl retinamide increases expression ISO RGD:1550273 6480464 Fenretinide results in increased expression of SMAD5 mRNA CTD PMID:28973697 5-aza-2'-deoxycytidine decreases expression ISO RGD:1550273 6480464 Decitabine results in decreased expression of SMAD5 mRNA CTD PMID:27915011 5-methoxypsoralen increases phosphorylation ISO RGD:1550273 6480464 5-methoxypsoralen results in increased phosphorylation of SMAD5 protein CTD PMID:17980360 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of SMAD5 mRNA CTD PMID:24780913 aflatoxin B1 increases expression ISO RGD:1349958 6480464 Aflatoxin B1 results in increased expression of SMAD5 mRNA CTD PMID:22100608 aflatoxin B1 increases methylation ISO RGD:1349958 6480464 Aflatoxin B1 results in increased methylation of SMAD5 intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:1349958 6480464 Aflatoxin B1 results in decreased methylation of SMAD5 gene CTD PMID:27153756 Aflatoxin B2 alpha increases methylation ISO RGD:1349958 6480464 aflatoxin B2 results in increased methylation of SMAD5 intron CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:1349958 6480464 Tretinoin results in decreased expression of SMAD5 mRNA CTD PMID:33167477 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of SMAD5 mRNA CTD PMID:16483693 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of SMAD5 mRNA CTD PMID:30779732 antirheumatic drug increases expression ISO RGD:1349958 6480464 Antirheumatic Agents results in increased expression of SMAD5 mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO RGD:1349958 6480464 aristolochic acid I results in decreased expression of SMAD5 protein modified form CTD PMID:22525892 aristolochic acid A multiple interactions ISO RGD:1349958 6480464 GREM1 mutant form inhibits the reaction [aristolochic acid I results in decreased expression of SMAD5 protein modified form] CTD PMID:22525892 arsane affects expression ISO RGD:1349958 6480464 Arsenic affects the expression of SMAD5 protein CTD PMID:24675094 arsane increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of SMAD5 protein CTD PMID:28903487 arsenic atom affects expression ISO RGD:1349958 6480464 Arsenic affects the expression of SMAD5 protein CTD PMID:24675094 arsenic atom increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of SMAD5 protein CTD PMID:28903487 aucubin increases expression ISO RGD:1349958 6480464 aucubin results in increased expression of SMAD5 protein CTD PMID:29408431 benzo[a]pyrene increases methylation ISO RGD:1349958 6480464 Benzo(a)pyrene results in increased methylation of SMAD5 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:1349958 6480464 Benzo(a)pyrene affects the methylation of SMAD5 intron CTD PMID:30157460 benzo[a]pyrene decreases methylation ISO RGD:1349958 6480464 Benzo(a)pyrene results in decreased methylation of SMAD5 5' UTR CTD PMID:27901495 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1349958 6480464 7 more ... CTD PMID:20018196 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1349958 6480464 7 more ... CTD PMID:26238291 bexarotene increases expression ISO RGD:1349958 6480464 bexarotene results in increased expression of SMAD5 mRNA CTD PMID:17178900 bisphenol A decreases expression ISO RGD:1349958 6480464 bisphenol A results in decreased expression of SMAD5 mRNA CTD PMID:22576693 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SMAD5 mRNA CTD PMID:30816183 more ... bisphenol A affects methylation ISO RGD:1550273 6480464 bisphenol A affects the methylation of SMAD5 promoter CTD PMID:27334623 bisphenol A increases expression ISO RGD:1550273 6480464 bisphenol A results in increased expression of SMAD5 mRNA CTD PMID:26063408 , PMID:33221593 cadmium atom multiple interactions ISO RGD:1349958 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMAD5 mRNA CTD PMID:35301059 cadmium dichloride multiple interactions ISO RGD:1349958 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMAD5 mRNA CTD PMID:35301059 caffeine increases phosphorylation ISO RGD:1349958 6480464 Caffeine results in increased phosphorylation of SMAD5 protein CTD PMID:35688186 carbon nanotube increases expression ISO RGD:1349958 6480464 Nanotubes, Carbon results in increased expression of SMAD5 mRNA CTD PMID:23634900 carbon nanotube increases expression ISO RGD:1550273 6480464 Nanotubes, Carbon results in increased expression of SMAD5 mRNA CTD PMID:25554681 CGP 52608 multiple interactions ISO RGD:1349958 6480464 CGP 52608 promotes the reaction [RORA protein binds to SMAD5 gene] CTD PMID:28238834 chlorpyrifos decreases expression ISO RGD:1550273 6480464 Chlorpyrifos results in decreased expression of SMAD5 mRNA CTD PMID:32715474 cocaine multiple interactions EXP 6480464 [Cocaine co-treated with Cocaine deficiency] inhibits the reaction [SMURF1 protein binds to SMAD5 protein modified form], [Cocaine co-treated with Cocaine deficiency] results in increased expression of and results in increased phosphorylation of SMAD5 protein CTD PMID:30158054 copper atom multiple interactions ISO RGD:1349958 6480464 [NSC 689534 binds to Copper] which results in decreased expression of SMAD5 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1349958 6480464 [NSC 689534 binds to Copper] which results in decreased expression of SMAD5 mRNA CTD PMID:20971185 copper(II) sulfate increases expression ISO RGD:1349958 6480464 Copper Sulfate results in increased expression of SMAD5 mRNA CTD PMID:19549813 coumarin decreases phosphorylation ISO RGD:1349958 6480464 coumarin results in decreased phosphorylation of SMAD5 protein CTD PMID:35688186 crocidolite asbestos decreases phosphorylation ISO RGD:1550273 6480464 Asbestos, Crocidolite results in decreased phosphorylation of SMAD5 protein CTD PMID:17975199 cyclosporin A decreases expression ISO RGD:1349958 6480464 Cyclosporine results in decreased expression of SMAD5 mRNA CTD PMID:27989131 deguelin increases expression ISO RGD:1349958 6480464 deguelin results in increased expression of SMAD5 mRNA CTD PMID:33512557 dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SMAD5 CTD PMID:20079400 dexamethasone multiple interactions ISO RGD:1550273 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA more ... CTD PMID:26492236 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [SMAD5 protein binds to AKT2 gene] CTD PMID:20079400 dimethylselenide multiple interactions ISO RGD:1349958 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of SMAD5-AS1 mRNA] which results in increased expression of SMAD5 mRNA, [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of SMAD5-AS1 mRNA] which results in increased expression of SMAD5 mRNA CTD PMID:33656867 dorsomorphin multiple interactions ISO RGD:1349958 6480464 dorsomorphin inhibits the reaction [GDF2 protein results in increased phosphorylation of SMAD5 protein] CTD PMID:23936038 ethanol increases expression ISO RGD:1550273 6480464 Ethanol results in increased expression of SMAD5 mRNA CTD PMID:30319688 ethyl methanesulfonate increases expression ISO RGD:1349958 6480464 Ethyl Methanesulfonate results in increased expression of SMAD5 mRNA CTD PMID:23649840 formaldehyde increases expression ISO RGD:1349958 6480464 Formaldehyde results in increased expression of SMAD5 mRNA CTD PMID:23649840 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of SMAD5 mRNA CTD PMID:33387578 glycerol 2-phosphate multiple interactions ISO RGD:1550273 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA more ... CTD PMID:26492236 hydrogen peroxide multiple interactions ISO RGD:1349958 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD5 protein CTD PMID:18951874 hydroxyl multiple interactions ISO RGD:1349958 6480464 [[Hydroxyl Radical results in increased oxidation of dimethylselenide] which results in increased expression of SMAD5-AS1 mRNA] which results in increased expression of SMAD5 mRNA CTD PMID:33656867 imperatorin increases phosphorylation ISO RGD:1550273 6480464 imperatorin results in increased phosphorylation of SMAD5 protein CTD PMID:17980360 ivermectin decreases expression ISO RGD:1349958 6480464 Ivermectin results in decreased expression of SMAD5 protein CTD PMID:32959892 L-ascorbic acid multiple interactions ISO RGD:1550273 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of SMAD5 mRNA more ... CTD PMID:26492236 lead diacetate multiple interactions ISO RGD:1550273 6480464 lead acetate inhibits the reaction [BMP2 protein results in increased phosphorylation of SMAD5 protein] CTD PMID:17805416 lead diacetate increases methylation EXP 6480464 lead acetate results in increased methylation of SMAD5 gene CTD PMID:29571894 leflunomide increases expression ISO RGD:1349958 6480464 leflunomide results in increased expression of SMAD5 mRNA CTD PMID:28988120 methyl methanesulfonate increases expression ISO RGD:1349958 6480464 Methyl Methanesulfonate results in increased expression of SMAD5 mRNA CTD PMID:23649840 ozone multiple interactions ISO RGD:1349958 6480464 [[Ozone results in increased oxidation of dimethylselenide] which results in increased expression of SMAD5-AS1 mRNA] which results in increased expression of SMAD5 mRNA CTD PMID:33656867 paracetamol multiple interactions ISO RGD:1550273 6480464 Acetaminophen results in decreased phosphorylation of [SMAD1 protein binds to SMAD5 protein binds to SMAD9 protein] CTD PMID:22610607 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of SMAD5 mRNA CTD PMID:33387578 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1550273 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SMAD5 mRNA CTD PMID:36331819 phencyclidine decreases expression ISO RGD:1550273 6480464 Phencyclidine results in decreased expression of SMAD5 mRNA CTD PMID:12105081 phenobarbital affects expression ISO RGD:1550273 6480464 Phenobarbital affects the expression of SMAD5 mRNA CTD PMID:23091169 picoxystrobin increases expression ISO RGD:1349958 6480464 picoxystrobin results in increased expression of SMAD5 mRNA CTD PMID:33512557 pirinixic acid decreases expression ISO RGD:1550273 6480464 pirinixic acid results in decreased expression of SMAD5 mRNA CTD PMID:20813756 quercetin decreases expression ISO RGD:1349958 6480464 Quercetin results in decreased expression of SMAD5 mRNA CTD PMID:15309432 resveratrol increases phosphorylation ISO RGD:1349958 6480464 resveratrol results in increased phosphorylation of SMAD5 protein CTD PMID:21745208 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SMAD5 mRNA CTD PMID:25905778 rotenone increases expression ISO RGD:1349958 6480464 Rotenone results in increased expression of SMAD5 mRNA CTD PMID:33512557 Salidroside multiple interactions ISO RGD:1550273 6480464 rhodioloside results in increased phosphorylation of and results in increased expression of SMAD5 protein CTD PMID:24929042 Salidroside increases expression ISO RGD:1550273 6480464 rhodioloside results in increased expression of SMAD5 mRNA CTD PMID:24929042 simvastatin multiple interactions ISO RGD:1550273 6480464 Simvastatin inhibits the reaction [TNF inhibits the reaction [BMP2 results in increased phosphorylation of SMAD5 protein]] CTD PMID:18310456 sirtinol decreases phosphorylation ISO RGD:1349958 6480464 sirtinol results in decreased phosphorylation of SMAD5 protein CTD PMID:21745208 sodium arsenite multiple interactions ISO RGD:1349958 6480464 EGF protein promotes the reaction [sodium arsenite inhibits the reaction [BMP6 protein results in increased phosphorylation of SMAD5 protein]], sodium arsenite inhibits the reaction [BMP6 protein results in increased phosphorylation of SMAD5 protein] CTD PMID:23566955 sodium arsenite decreases expression ISO RGD:1550273 6480464 sodium arsenite results in decreased expression of SMAD5 mRNA CTD PMID:16014739 tert-butyl hydroperoxide decreases methylation ISO RGD:1349958 6480464 tert-Butylhydroperoxide results in decreased methylation of SMAD5 gene CTD PMID:27509014 tert-butyl hydroperoxide increases expression ISO RGD:1349958 6480464 tert-Butylhydroperoxide results in increased expression of SMAD5 mRNA CTD PMID:27509014 testosterone enanthate affects expression ISO RGD:1349958 6480464 testosterone enanthate affects the expression of SMAD5 mRNA CTD PMID:17440010 theophylline multiple interactions ISO RGD:1349958 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of SMAD5 protein CTD PMID:18951874 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of SMAD5 mRNA CTD PMID:34492290 trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of SMAD5 gene CTD PMID:27618143 triptonide increases expression ISO RGD:1550273 6480464 triptonide results in increased expression of SMAD5 mRNA CTD PMID:33045310 valproic acid decreases methylation ISO RGD:1349958 6480464 Valproic Acid results in decreased methylation of SMAD5 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1550273 6480464 Valproic Acid affects the expression of SMAD5 mRNA CTD PMID:17963808 valproic acid decreases expression ISO RGD:1349958 6480464 Valproic Acid results in decreased expression of SMAD5 mRNA CTD PMID:23179753 more ... vitamin E decreases expression ISO RGD:1349958 6480464 Vitamin E results in decreased expression of SMAD5 mRNA CTD PMID:19244175
