SRY (sex determining region Y) - Rat Genome Database

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Gene: SRY (sex determining region Y) Canis lupus familiaris
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Symbol: SRY
Name: sex determining region Y
RGD ID: 40919389
Description: ENCODES a protein that exhibits DNA binding, bending (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor binding (ortholog); INVOLVED IN male gonad development (ortholog); male sex determination (ortholog); negative regulation of gene expression (ortholog); ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); 46,XX sex reversal 1 (ortholog); 46,XY sex reversal (ortholog); FOUND IN nucleus (ortholog); transcription regulator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sex determining region Y protein; sex-determining region Y protein; TDF; Testis-determining factor
RGD Orthologs
Human
Mouse
Rat
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position: No map positions available.


References
Additional References at PubMed
PMID:34664728  


Genomics

Comparative Map Data
SRY
(Canis lupus familiaris - dog)
No map positions available.
SRY
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38Y2,786,855 - 2,787,682 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblY2,786,855 - 2,787,682 (-)EnsemblGRCh38hg38GRCh38
GRCh37Y2,654,896 - 2,655,723 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36Y2,714,896 - 2,715,792 (-)NCBINCBI36Build 36hg18NCBI36
Build 34Y2,698,256 - 2,699,153NCBI
CeleraX88,844,082 - 88,844,978 (-)NCBICelera
Cytogenetic MapYp11.2NCBI
HuRefY7,900 - 8,786 (-)NCBIHuRef
T2T-CHM13v2.0Y2,463,695 - 2,464,522 (-)NCBIT2T-CHM13v2.0
Sry
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39Y2,662,471 - 2,663,658 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblY2,662,471 - 2,663,658 (-)EnsemblGRCm39 Ensembl
GRCm38Y2,662,471 - 2,663,658 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblY2,662,471 - 2,663,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv37Y1,918,381 - 1,919,568 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36Y1,947,341 - 1,948,528 (-)NCBIMGSCv36mm8
CeleraY5,570,827 - 5,572,014 (+)NCBICelera
Cytogenetic MapYpterNCBI
Sry
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8Y465,260 - 465,772 (+)NCBIGRCr8
mRatBN7.2Y441,525 - 442,037 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_UtxY1,408,967 - 1,409,476 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0Y1,568,514 - 1,569,023 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0Y780,432 - 780,941 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0Y327,176 - 327,685 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblY327,166 - 329,299 (+)EnsemblRnor6.0rn6Rnor6.0
Cytogenetic MapYq11NCBI
SRY
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2Y44,391,717 - 44,406,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1Y2,531,737 - 2,532,564 (-)NCBINHGRI_mPanPan1
SRY
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblY40,484,990 - 40,485,700 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1Y40,484,990 - 40,485,700 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2Y279,587 - 280,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapYp12-p13NCBI
SRY
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X927,143 - 928,924 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX927,692 - 928,303 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2


Expression

RNA-SEQ Expression


Sequence


Protein Sequences
Protein RefSeqs XP_038307340 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC48474 (Get FASTA)   NCBI Sequence Viewer  
  AAD40225 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00030013218.1
  ENSCAFP00845031662
  ENSCAFP00845031662.1
GenBank Protein Q9XT60 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
HMG box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00030008259 UniProtKB/Swiss-Prot
  ENSCAFG00845022918 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00030015158.1 UniProtKB/Swiss-Prot
  ENSCAFT00845040434 ENTREZGENE
  ENSCAFT00845040434.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.30.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SRY UniProtKB/Swiss-Prot
  SRY-related_HMG-box_TFs UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene SRY ENTREZGENE
PANTHER PTHR10270:SF199 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOX TRANSCRIPTION FACTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF SRY UniProtKB/Swiss-Prot
PROSITE HMG_BOX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HMG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q28251_CANLF UniProtKB/TrEMBL
  Q9XT60 ENTREZGENE, UniProtKB/Swiss-Prot