Esr2<sup><i>em1Soar</i></sup> (estrogen receptor 2; ZFN induced mutant 1, Soar) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Esr2em1Soar (estrogen receptor 2; ZFN induced mutant 1, Soar) Rattus norvegicus
Analyze
Symbol: Esr2em1Soar
Name: estrogen receptor 2; ZFN induced mutant 1, Soar
RGD ID: 40902840
Description: Zinc finger nuclease targeting of exon 4 of the rat estrogen receptor-2 gene resulting in the deletion of exon 4
ASSOCIATED WITH abnormal circulating androgen level; abnormal proestrus; absent corpus luteum; ASSOCIATED WITH Female Infertility
Type: allele  of Esr2  
Previously known as: Esr2^[em1Soar]
Is Marker For: Strains:   SD-Esr2em1Soar  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position: No map positions available.


References

References - curated
# Reference Title Reference Citation
1. ESR2 regulates granulosa cell genes essential for follicle maturation and ovulation. Khristi V, etal., Mol Cell Endocrinol. 2018 Oct 15;474:214-226. doi: 10.1016/j.mce.2018.03.012. Epub 2018 Mar 24.
2. Defining the Role of Estrogen Receptor β in the Regulation of Female Fertility. Rumi MAK, etal., Endocrinology. 2017 Jul 1;158(7):2330-2343. doi: 10.1210/en.2016-1916.

Genomics


Related Rat Strains
The following Strains have been annotated to Esr2em1Soar
SD-Esr2em1Soar    


Expression


Sequence

Nucleotide Sequences


Additional Information