DEFA4 (defensin alpha 4) - Rat Genome Database

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Gene: DEFA4 (defensin alpha 4) Chlorocebus sabaeus
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Symbol: DEFA4
Name: defensin alpha 4
RGD ID: 40898391
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to bacterium (ortholog); innate immune response (ortholog); ASSOCIATED WITH Parkinson's disease (ortholog); thymoma (ortholog); FOUND IN azurophil granule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: neutrophil defensin 4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap187,744,300 - 7,762,396 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605448,826,975 - 48,836,477 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0



Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DEFA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap187,744,300 - 7,762,396 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366605448,826,975 - 48,836,477 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
DEFA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3886,935,820 - 6,938,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl86,935,820 - 6,938,313 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh3786,793,342 - 6,795,828 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3686,780,755 - 6,783,196 (-)NCBIBuild 36Build 36hg18NCBI36
Build 3486,780,754 - 6,783,196NCBI
Celera86,770,132 - 6,772,573 (-)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef86,572,881 - 6,575,322 (-)NCBIHuRef
CHM1_186,882,470 - 6,884,911 (-)NCBICHM1_1
T2T-CHM13v2.086,690,512 - 6,692,998 (-)NCBIT2T-CHM13v2.0
Defa31
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39821,681,589 - 21,682,566 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl821,681,585 - 21,682,566 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38821,191,573 - 21,192,550 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl821,191,614 - 21,192,549 (+)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37822,331,252 - 22,332,229 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36822,686,366 - 22,686,536 (+)NCBIMGSCv36mm8
Celera820,990,359 - 20,991,328 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map810.35NCBI
Np4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81677,197,061 - 77,199,713 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1677,197,065 - 77,199,642 (-)EnsemblGRCr8
GRCr8 Ensembl1677,121,639 - 77,122,502 (-)EnsemblGRCr8
mRatBN7.21670,494,607 - 70,497,261 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1670,342,529 - 70,497,202 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1675,771,469 - 75,774,026 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01679,217,054 - 79,219,596 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01674,466,481 - 74,469,025 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1677,145,146 - 77,147,711 (-)NCBI
Lyon_Normotensive1678,518,251 - 78,520,816 (-)NCBI
Lyon_Hypertensive1679,019,242 - 79,021,807 (-)NCBI
F344_StmMcwi1675,181,105 - 75,183,679 (-)NCBI
Rnor_6.01675,478,548 - 75,481,146 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,414,786 - 75,481,115 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.01675,079,890 - 75,082,489 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41675,284,693 - 75,337,014 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1668,357,038 - 68,359,592 (-)NCBICelera
RGSC_v3.11675,284,957 - 75,337,279 (-)NCBI
Cytogenetic Map16q12.5NCBI
DEFA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2721,738,846 - 21,741,331 (-)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v08344,350 - 346,835 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.186,938,152 - 6,940,669 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl86,938,152 - 6,940,669 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_073018625   ⟹   XP_072874726
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
mChlSab1.0.hap187,744,300 - 7,762,396 (-)NCBI
Protein Sequences
Protein RefSeqs XP_072874726 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_072874726   ⟸   XM_073018625


Additional Information

Database Acc Id Source(s)
NCBI Gene DEFA4 ENTREZGENE