SLC12A7 (solute carrier family 12 member 7) - Rat Genome Database

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Gene: SLC12A7 (solute carrier family 12 member 7) Pan paniscus
Analyze
Symbol: SLC12A7
Name: solute carrier family 12 member 7
RGD ID: 402528256
Description: ENCODES a protein that exhibits potassium:chloride symporter activity (inferred); protein kinase binding (inferred); symporter activity (inferred); INVOLVED IN cell volume homeostasis (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal dominant dyskeratosis congenita 2 (ortholog); dopamine transporter deficiency syndrome (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred); protein-containing complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,297,648 - 1,358,631 (-)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,094,769 - 1,147,759 (-)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC12A7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,297,648 - 1,358,631 (-)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,094,769 - 1,147,759 (-)Ensemblpanpan1.1panPan2
SLC12A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3851,050,384 - 1,155,899 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl51,050,384 - 1,112,063 (-)EnsemblGRCh38hg38GRCh38
GRCh3751,050,499 - 1,112,178 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,103,489 - 1,165,172 (-)NCBINCBI36Build 36hg18NCBI36
Build 3451,103,499 - 1,165,109NCBI
Celera51,087,603 - 1,137,533 (-)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef51,032,225 - 1,074,697 (-)NCBIHuRef
CHM1_151,050,309 - 1,109,639 (-)NCBICHM1_1
T2T-CHM13v2.05955,618 - 1,061,601 (-)NCBIT2T-CHM13v2.0
Slc12a7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391373,881,172 - 73,964,873 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1373,881,213 - 73,964,873 (+)EnsemblGRCm39 Ensembl
GRCm381373,733,052 - 73,816,754 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1373,733,094 - 73,816,754 (+)EnsemblGRCm38mm10GRCm38
MGSCv371373,901,145 - 73,954,191 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361374,229,699 - 74,282,745 (+)NCBIMGSCv36mm8
Celera1376,093,026 - 76,146,073 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.15NCBI
Slc12a7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,301,243 - 31,382,825 (-)NCBIGRCr8
mRatBN7.2129,472,692 - 29,554,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,472,692 - 29,554,302 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,273,827 - 29,327,212 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,273,677 - 35,327,062 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,474,455 - 29,527,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,086,755 - 32,167,950 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,086,755 - 32,141,036 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,511,432 - 33,592,624 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,281,826 - 30,334,183 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1130,283,750 - 30,337,129 (-)NCBI
Celera128,120,766 - 28,174,109 (-)NCBICelera
Cytogenetic Map1p11NCBI
Slc12a7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504530,343 - 568,569 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955504529,183 - 589,728 (-)NCBIChiLan1.0ChiLan1.0
SLC12A7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,411,521 - 11,442,175 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,411,626 - 11,440,957 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3415,916,047 - 15,953,273 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,306,873 - 11,344,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,278,297 - 11,369,935 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,357,510 - 11,394,729 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,337,208 - 11,374,410 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,548,126 - 11,585,343 (+)NCBIUU_Cfam_GSD_1.0
Slc12a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,468,120 - 244,505,057 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815636,184 - 665,019 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815629,185 - 666,342 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC12A7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,357,010 - 79,396,656 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,356,868 - 79,396,652 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC12A7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.14890,213 - 989,650 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl4890,202 - 964,263 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,446,259 - 35,506,531 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc12a7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751506,040 - 544,365 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751508,902 - 544,319 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000035093   ⟹   ENSPPAP00000012428
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl51,094,769 - 1,147,759 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000035095   ⟹   ENSPPAP00000012430
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl51,096,298 - 1,140,518 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000035098   ⟹   ENSPPAP00000012433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl51,096,724 - 1,135,316 (-)Ensembl
RefSeq Acc Id: XM_063604362   ⟹   XP_063460432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v241,297,648 - 1,358,631 (-)NCBI
RefSeq Acc Id: XM_063604363   ⟹   XP_063460433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v241,297,648 - 1,358,631 (-)NCBI
Protein Sequences
Protein RefSeqs XP_063460432 (Get FASTA)   NCBI Sequence Viewer  
  XP_063460433 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012428.1
  ENSPPAP00000012430.1
  ENSPPAP00000012433.1
Ensembl Acc Id: ENSPPAP00000012433   ⟸   ENSPPAT00000035098
Ensembl Acc Id: ENSPPAP00000012430   ⟸   ENSPPAT00000035095
Ensembl Acc Id: ENSPPAP00000012428   ⟸   ENSPPAT00000035093
RefSeq Acc Id: XP_063460432   ⟸   XM_063604362
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A558 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063460433   ⟸   XM_063604363
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A558 (UniProtKB/TrEMBL)
Protein Domains
Amino acid permease/ SLC12A   SLC12A transporter C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029396 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035093.1 UniProtKB/TrEMBL
  ENSPPAT00000035095.1 UniProtKB/TrEMBL
  ENSPPAT00000035098.1 UniProtKB/TrEMBL
Gene3D-CATH Amino acid/polyamine transporter I UniProtKB/TrEMBL
InterPro AA-permease/SLC12A_dom UniProtKB/TrEMBL
  KCL_cotranspt UniProtKB/TrEMBL
  SLC12_C UniProtKB/TrEMBL
  SLC12A_fam UniProtKB/TrEMBL
NCBI Gene SLC12A7 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 12 MEMBER 7 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS UniProtKB/TrEMBL
Pfam AA_permease UniProtKB/TrEMBL
  SLC12 UniProtKB/TrEMBL
PRINTS KCLTRNSPORT UniProtKB/TrEMBL
UniProt A0A2R9A558 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A561_PANPA UniProtKB/TrEMBL
  A0A2R9A6C4_PANPA UniProtKB/TrEMBL