FAM177A1 (family with sequence similarity 177 member A1) - Rat Genome Database

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Gene: FAM177A1 (family with sequence similarity 177 member A1) Homo sapiens
Analyze
Symbol: FAM177A1
Name: family with sequence similarity 177 member A1
RGD ID: 30308104
HGNC Page HGNC:19829
Description: This gene encodes a member of a conserved protein family. Alternative splicing results in multiple transcript variants. This gene is thought to be associated with susceptibility to juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C14orf24; protein FAM177A1
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Related Pseudogenes: FAM177A1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381435,044,907 - 35,083,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1435,045,117 - 35,116,630 (+)EnsemblGRCh38hg38GRCh38
GRCh371435,514,113 - 35,552,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map14q13.2NCBI
HuRef1415,626,781 - 15,665,252 (+)NCBIHuRef
CHM1_11435,513,864 - 35,552,320 (+)NCBICHM1_1
T2T-CHM13v2.01429,241,864 - 29,280,312 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Macrocephaly  (IAGP)
References
Additional References at PubMed
PMID:12477932   PMID:12766061   PMID:14702039   PMID:15489334   PMID:19663910   PMID:20136554   PMID:26186194   PMID:26496610   PMID:27432908   PMID:27488439   PMID:28514442   PMID:32296183  
PMID:32814053   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34597346   PMID:34799425   PMID:36215168   PMID:38569033   PMID:38767059  


Genomics

Comparative Map Data
FAM177A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381435,044,907 - 35,083,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1435,045,117 - 35,116,630 (+)EnsemblGRCh38hg38GRCh38
GRCh371435,514,113 - 35,552,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map14q13.2NCBI
HuRef1415,626,781 - 15,665,252 (+)NCBIHuRef
CHM1_11435,513,864 - 35,552,320 (+)NCBICHM1_1
T2T-CHM13v2.01429,241,864 - 29,280,312 (+)NCBIT2T-CHM13v2.0
Fam177a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,171,313 - 55,188,889 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,171,254 - 55,188,889 (+)EnsemblGRCm39 Ensembl
GRCm381255,124,435 - 55,142,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,124,469 - 55,142,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv371256,225,515 - 56,243,091 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361249,662,763 - 49,680,343 (+)NCBIMGSCv36mm8
MGSCv361256,042,658 - 56,060,234 (+)NCBIMGSCv36mm8
Celera1256,419,532 - 56,457,279 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1223.87NCBI
Fam177a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,367,780 - 78,382,703 (+)NCBIGRCr8
mRatBN7.2672,632,628 - 72,647,553 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,632,623 - 72,647,553 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx673,055,248 - 73,070,186 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,361,597 - 73,376,537 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0672,790,230 - 72,805,149 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,041,080 - 76,055,912 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,041,669 - 76,053,759 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,577,837 - 85,592,624 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,501,445 - 75,513,944 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera671,473,300 - 71,488,310 (+)NCBICelera
Cytogenetic Map6q23NCBI
FAM177A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1813,844,565 - 13,862,619 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl813,844,685 - 13,860,889 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha813,641,509 - 13,659,550 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0813,951,498 - 13,969,550 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl813,951,474 - 13,968,204 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1813,653,177 - 13,671,230 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0813,717,477 - 13,735,558 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0814,006,731 - 14,024,846 (+)NCBIUU_Cfam_GSD_1.0
FAM177A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl764,788,077 - 64,808,473 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1764,788,829 - 64,808,640 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2769,618,807 - 69,636,919 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in FAM177A1
16 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 14q13.1-13.3(chr14:34450934-36880151)x1 copy number loss See cases [RCV000051492] Chr14:34450934..36880151 [GRCh38]
Chr14:34920140..37349356 [GRCh37]
Chr14:33989891..36419107 [NCBI36]
Chr14:14q13.1-13.3		 pathogenic
GRCh37/hg19 14q13.1-13.2(chr14:35232984-35652742)x3 copy number gain not provided [RCV000683606] Chr14:35232984..35652742 [GRCh37]
Chr14:14q13.1-13.2		 uncertain significance
GRCh37/hg19 14q13.2(chr14:35395019-35783469)x3 copy number gain not provided [RCV001006615] Chr14:35395019..35783469 [GRCh37]
Chr14:14q13.2		 uncertain significance
GRCh37/hg19 14q11.2-32.33(chr14:20511673-107285437) copy number gain See cases [RCV000512041] Chr14:20511673..107285437 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q11.2-21.3(chr14:20043513-48642042)x3 copy number gain See cases [RCV000143748] Chr14:20043513..48642042 [GRCh38]
Chr14:20511672..49111245 [GRCh37]
Chr14:19581512..48180995 [NCBI36]
Chr14:14q11.2-21.3		 pathogenic
GRCh38/hg38 14q11.2-21.2(chr14:20196945-45284802)x1 copy number loss See cases [RCV000051485] Chr14:20196945..45284802 [GRCh38]
Chr14:20665104..45754005 [GRCh37]
Chr14:19734944..44823755 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh37/hg19 14q11.1-32.33(chr14:19000422-107289053)x3 copy number gain not provided [RCV000738412] Chr14:19000422..107289053 [GRCh37]
Chr14:14q11.1-32.33		 pathogenic
GRCh38/hg38 14q13.1-21.1(chr14:33880412-42359485)x1 copy number loss See cases [RCV000142211] Chr14:33880412..42359485 [GRCh38]
Chr14:34349618..42828688 [GRCh37]
Chr14:33419369..41898438 [NCBI36]
Chr14:14q13.1-21.1		 pathogenic
NM_173607.5(FAM177A1):c.174C>T (p.Asn58=) single nucleotide variant not provided [RCV000904125] Chr14:35053286 [GRCh38]
Chr14:35522492 [GRCh37]
Chr14:14q13.2		 benign|likely benign
GRCh38/hg38 14q11.2-21.1(chr14:23548960-41983402)x1 copy number loss See cases [RCV000051490] Chr14:23548960..41983402 [GRCh38]
Chr14:24018169..42452605 [GRCh37]
Chr14:23088009..41522355 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
GRCh38/hg38 14q11.2-21.1(chr14:20000611-38984415)x3 copy number gain See cases [RCV000053803] Chr14:20000611..38984415 [GRCh38]
Chr14:20468770..39453619 [GRCh37]
Chr14:19538610..38523370 [NCBI36]
Chr14:14q11.2-21.1		 pathogenic
GRCh37/hg19 14q13.2(chr14:35546356-35546423) copy number loss Macrocephaly [RCV001195143] Chr14:35546356..35546423 [GRCh37]
Chr14:14q13.2		 uncertain significance
GRCh38/hg38 14q13.2(chr14:35068276-35231604)x3 copy number gain See cases [RCV000139964] Chr14:35068276..35231604 [GRCh38]
Chr14:35537482..35700810 [GRCh37]
Chr14:34607233..34770561 [NCBI36]
Chr14:14q13.2		 likely benign
NC_000014.8:g.(?_35182071)_(35873850_?)del deletion Ectodermal dysplasia and immunodeficiency 2 [RCV003107717]|not provided [RCV003113213] Chr14:35182071..35873850 [GRCh37]
Chr14:14q13.1-13.2		 uncertain significance|no classifications from unflagged records
GRCh37/hg19 14q11.2-21.1(chr14:20511672-42881888)x3 copy number gain not provided [RCV001249358] Chr14:20511672..42881888 [GRCh37]
Chr14:14q11.2-21.1		 not provided
GRCh38/hg38 14q13.1-13.3(chr14:33762166-36191750)x1 copy number loss See cases [RCV000142534] Chr14:33762166..36191750 [GRCh38]
Chr14:34231372..36660956 [GRCh37]
Chr14:33301123..35730707 [NCBI36]
Chr14:14q13.1-13.3		 uncertain significance
GRCh38/hg38 14q11.2-21.2(chr14:20022693-44093672)x3 copy number gain See cases [RCV000143186] Chr14:20022693..44093672 [GRCh38]
Chr14:20490852..44562875 [GRCh37]
Chr14:19560692..43632625 [NCBI36]
Chr14:14q11.2-21.2		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20043514-106877229)x3 copy number gain See cases [RCV000143373] Chr14:20043514..106877229 [GRCh38]
Chr14:20511673..107285437 [GRCh37]
Chr14:19581513..106356482 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-21.2(chr14:20511672-44829030)x3 copy number gain not provided [RCV001006605] Chr14:20511672..44829030 [GRCh37]
Chr14:14q11.2-21.2		 pathogenic
NM_173607.5(FAM177A1):c.366dup (p.Trp123fs) duplication Macrocephaly [RCV000162180] Chr14:35077175..35077176 [GRCh38]
Chr14:35546381..35546382 [GRCh37]
Chr14:14q13.2		 likely pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19327823-107287663)x3 copy number gain not provided [RCV000738414] Chr14:19327823..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19280733-107287663)x3 copy number gain not provided [RCV000738413] Chr14:19280733..107287663 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh38/hg38 14q13.2-21.2(chr14:35068276-43994777)x1 copy number loss See cases [RCV000137841] Chr14:35068276..43994777 [GRCh38]
Chr14:35537482..44463980 [GRCh37]
Chr14:34607233..43533730 [NCBI36]
Chr14:14q13.2-21.2		 pathogenic
GRCh38/hg38 14q12-21.1(chr14:30382554-37712341)x1 copy number loss See cases [RCV000135334] Chr14:30382554..37712341 [GRCh38]
Chr14:30851760..38181546 [GRCh37]
Chr14:29921511..37251297 [NCBI36]
Chr14:14q12-21.1		 pathogenic
GRCh38/hg38 14q12-21.2(chr14:30670314-44990595)x3 copy number gain See cases [RCV000052292] Chr14:30670314..44990595 [GRCh38]
Chr14:31139520..45459798 [GRCh37]
Chr14:30209271..44529548 [NCBI36]
Chr14:14q12-21.2		 pathogenic
GRCh37/hg19 14q11.2-22.2(chr14:23164384-54733411)x3 copy number gain See cases [RCV000447658] Chr14:23164384..54733411 [GRCh37]
Chr14:14q11.2-22.2		 pathogenic
NC_000014.9:g.35077780_35087566del deletion FAM177A1-related disorder [RCV001090143] Chr14:35077780..35087566 [GRCh38]
Chr14:35546986..35556772 [GRCh37]
Chr14:14q13.2		 likely pathogenic
GRCh38/hg38 14q12-21.2(chr14:30792271-44685131)x1 copy number loss See cases [RCV000143063] Chr14:30792271..44685131 [GRCh38]
Chr14:31261477..45154334 [GRCh37]
Chr14:30331228..44224084 [NCBI36]
Chr14:14q12-21.2		 pathogenic
GRCh38/hg38 14q11.2-32.33(chr14:20151149-106855263)x3 copy number gain See cases [RCV000135543] Chr14:20151149..106855263 [GRCh38]
Chr14:20619308..107263478 [GRCh37]
Chr14:19689148..106334523 [NCBI36]
Chr14:14q11.2-32.33		 pathogenic
NC_000014.9:g.35044389_35052476del deletion FAM177A1-related disorder [RCV001090158] Chr14:35044389..35052476 [GRCh38]
Chr14:35513595..35521682 [GRCh37]
Chr14:14q13.2		 likely pathogenic
GRCh37/hg19 14q11.2-32.33(chr14:19794561-107234280)x3 copy number gain See cases [RCV000446256] Chr14:19794561..107234280 [GRCh37]
Chr14:14q11.2-32.33		 pathogenic
GRCh37/hg19 14q11.2-21.3(chr14:20511672-47481203) copy number gain Seizure [RCV002280625] Chr14:20511672..47481203 [GRCh37]
Chr14:14q11.2-21.3		 pathogenic
GRCh37/hg19 14q13.1-21.2(chr14:33608925-44570367) copy number loss Poor motor coordination [RCV001352634] Chr14:33608925..44570367 [GRCh37]
Chr14:14q13.1-21.2		 pathogenic
NM_173607.5(FAM177A1):c.366_367dup (p.Trp123fs) duplication not provided [RCV002248323] Chr14:35077174..35077175 [GRCh38]
Chr14:35546380..35546381 [GRCh37]
Chr14:14q13.2		 uncertain significance
NC_000014.8:g.(21162263_36986276)_(36987308_50713602)del deletion Brain-lung-thyroid syndrome [RCV002221171] Chr14:36986276..36987308 [GRCh37]
Chr14:14q11.2-21.3		 pathogenic
GRCh37/hg19 14q13.1-13.3(chr14:34904407-36784136)x1 copy number loss not provided [RCV002511791] Chr14:34904407..36784136 [GRCh37]
Chr14:14q13.1-13.3		 pathogenic
NM_173607.5(FAM177A1):c.641A>G (p.Asn214Ser) single nucleotide variant not specified [RCV004088053] Chr14:35081158 [GRCh38]
Chr14:35550364 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.439G>C (p.Val147Leu) single nucleotide variant not specified [RCV004124691] Chr14:35078959 [GRCh38]
Chr14:35548165 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.704C>T (p.Pro235Leu) single nucleotide variant not specified [RCV004157273] Chr14:35081221 [GRCh38]
Chr14:35550427 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.172A>G (p.Asn58Asp) single nucleotide variant not specified [RCV004185061] Chr14:35053284 [GRCh38]
Chr14:35522490 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.661A>C (p.Ser221Arg) single nucleotide variant not specified [RCV004131575] Chr14:35081178 [GRCh38]
Chr14:35550384 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.359C>T (p.Pro120Leu) single nucleotide variant not specified [RCV004328786] Chr14:35077169 [GRCh38]
Chr14:35546375 [GRCh37]
Chr14:14q13.2		 uncertain significance
GRCh37/hg19 14q11.2-23.1(chr14:20511673-61826023)x3 copy number gain not provided [RCV003485022] Chr14:20511673..61826023 [GRCh37]
Chr14:14q11.2-23.1		 pathogenic
GRCh37/hg19 14q13.1-13.2(chr14:35059946-35787671)x3 copy number gain not specified [RCV003987068] Chr14:35059946..35787671 [GRCh37]
Chr14:14q13.1-13.2		 uncertain significance
GRCh37/hg19 14q12-21.2(chr14:29190489-45325177)x1 copy number loss not specified [RCV003987053] Chr14:29190489..45325177 [GRCh37]
Chr14:14q12-21.2		 pathogenic
NM_173607.5(FAM177A1):c.196G>A (p.Glu66Lys) single nucleotide variant not specified [RCV004380994] Chr14:35053308 [GRCh38]
Chr14:35522514 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.338C>T (p.Pro113Leu) single nucleotide variant not specified [RCV004380995] Chr14:35053450 [GRCh38]
Chr14:35522656 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.83C>T (p.Pro28Leu) single nucleotide variant not specified [RCV004102904] Chr14:35046546 [GRCh38]
Chr14:35515752 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.383G>A (p.Arg128Gln) single nucleotide variant not specified [RCV004332150] Chr14:35077193 [GRCh38]
Chr14:35546399 [GRCh37]
Chr14:14q13.2		 uncertain significance
GRCh37/hg19 14q13.1-13.3(chr14:34585231-37477843)x1 copy number loss not provided [RCV003483199] Chr14:34585231..37477843 [GRCh37]
Chr14:14q13.1-13.3		 pathogenic
GRCh37/hg19 14q13.2(chr14:35360640-35936592)x3 copy number gain not specified [RCV003987042] Chr14:35360640..35936592 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.539A>G (p.Glu180Gly) single nucleotide variant not specified [RCV004380996] Chr14:35081056 [GRCh38]
Chr14:35550262 [GRCh37]
Chr14:14q13.2		 uncertain significance
NM_173607.5(FAM177A1):c.81G>T (p.Glu27Asp) single nucleotide variant not specified [RCV004380997] Chr14:35046544 [GRCh38]
Chr14:35515750 [GRCh37]
Chr14:14q13.2		 uncertain significance

QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
406975682GWAS624658_Hbipolar disorder, schizophrenia, response to lithium ion QTL GWAS624658 (human)2e-08bipolar disorder, schizophrenia, response to lithium ion143506992535069926Human
406947494GWAS596470_Hprotein FAM177A1 measurement QTL GWAS596470 (human)3e-425protein FAM177A1 measurement143504700735047008Human
406995737GWAS644713_Hlevel of protein FAM177A1 in blood serum QTL GWAS644713 (human)8e-18level of protein FAM177A1 in blood serum143504700735047008Human
406925981GWAS574957_HC-reactive protein measurement QTL GWAS574957 (human)2e-08C-reactive protein measurementblood C-reactive protein level (CMO:0003160)143505881735058818Human
407337978GWAS986954_HBMI-adjusted hip circumference QTL GWAS986954 (human)5e-09BMI-adjusted hip circumferencehip circumference (CMO:0000014)143504589035045891Human
407213611GWAS862587_Hblood protein measurement QTL GWAS862587 (human)4e-155blood protein measurementblood protein measurement (CMO:0000028)143504700735047008Human
406892335GWAS541311_Hprotein FAM177A1 measurement QTL GWAS541311 (human)1e-144protein FAM177A1 measurement143504640035046401Human


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_054633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001079519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001289022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_173607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI148967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK096173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL049776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG700755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX640984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD678775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR749796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: NM_001079519   ⟹   NP_001072987
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381435,044,907 - 35,083,383 (+)NCBI
T2T-CHM13v2.01429,241,864 - 29,280,312 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001289022   ⟹   NP_001275951
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381435,046,272 - 35,083,378 (+)NCBI
T2T-CHM13v2.01429,243,229 - 29,280,307 (+)NCBI
Sequence:
RefSeq Acc Id: NM_173607   ⟹   NP_775878
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381435,046,272 - 35,083,378 (+)NCBI
T2T-CHM13v2.01429,243,229 - 29,280,307 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001072987   ⟸   NM_001079519
- Peptide Label: isoform 2
- UniProtKB: Q68CT2 (UniProtKB/Swiss-Prot),   Q8N128 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001275951   ⟸   NM_001289022
- Peptide Label: isoform 2
- UniProtKB: Q68CT2 (UniProtKB/Swiss-Prot),   Q8N128 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_775878   ⟸   NM_173607
- Peptide Label: isoform 1 precursor
- UniProtKB: Q8N128 (UniProtKB/Swiss-Prot)
- Sequence:

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8N128-F1-model_v2 AlphaFold Q8N128 1-213 view protein structure

Promoters
RGD ID:7227413
Promoter ID:EPDNEW_H19451
Type:initiation region
Name:FAM177A1_1
Description:family with sequence similarity 177 member A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381435,046,366 - 35,046,426EPDNEW

Additional Information

Database Acc Id Source(s)
COSMIC FAM177A1 COSMIC
Ensembl Genes ENSG00000151327 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000280987 ENTREZGENE
  ENST00000280987.9 UniProtKB/Swiss-Prot
  ENST00000382406 ENTREZGENE
  ENST00000382406.7 UniProtKB/Swiss-Prot
  ENST00000553852.1 UniProtKB/TrEMBL
  ENST00000553955.2 UniProtKB/TrEMBL
  ENST00000554052.2 UniProtKB/TrEMBL
  ENST00000554794.1 UniProtKB/TrEMBL
  ENST00000555211 ENTREZGENE
  ENST00000555211.5 UniProtKB/TrEMBL
  ENST00000555211.6 UniProtKB/Swiss-Prot
  ENST00000555260.1 UniProtKB/TrEMBL
  ENST00000556858.2 UniProtKB/TrEMBL
  ENST00000699514.1 UniProtKB/Swiss-Prot
  ENST00000699515.1 UniProtKB/Swiss-Prot
  ENST00000699516.1 UniProtKB/TrEMBL
GTEx ENSG00000151327 GTEx
HGNC ID HGNC:19829 ENTREZGENE
Human Proteome Map FAM177A1 Human Proteome Map
InterPro FAM177 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:283635 UniProtKB/Swiss-Prot
NCBI Gene FAM177A1 ENTREZGENE
OMIM 619181 OMIM
PANTHER HIGH MOBILITY GROUP AT-HOOK 2 UniProtKB/TrEMBL
  PROTEIN FAM177A1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN GVQW1-RELATED UniProtKB/TrEMBL
  PTHR31206 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAM177 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162387378 PharmGKB
UniProt A0A087X212_HUMAN UniProtKB/TrEMBL
  A0A1Y8EH40_HUMAN UniProtKB/TrEMBL
  A0A8V8TNB7_HUMAN UniProtKB/TrEMBL
  F177A_HUMAN UniProtKB/Swiss-Prot
  G3V3Z5_HUMAN UniProtKB/TrEMBL
  G3V583_HUMAN UniProtKB/TrEMBL
  H0YJC3_HUMAN UniProtKB/TrEMBL
  H0YJX7_HUMAN UniProtKB/TrEMBL
  Q68CT2 ENTREZGENE
  Q8N128 ENTREZGENE
  R4GN97_HUMAN UniProtKB/TrEMBL
UniProt Secondary Q68CT2 UniProtKB/Swiss-Prot