Mipep (mitochondrial intermediate peptidase) - Rat Genome Database

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Gene: Mipep (mitochondrial intermediate peptidase) Heterocephalus glaber
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Symbol: Mipep
Name: mitochondrial intermediate peptidase
RGD ID: 18932871
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN peptide metabolic process (inferred); protein processing involved in protein targeting to mitochondrion (inferred); proteolysis (inferred); PARTICIPATES IN presequence pathway of mitochondrial protein import; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2C (ortholog); cardiomyopathy (ortholog); combined oxidative phosphorylation deficiency 31 (ortholog); FOUND IN mitochondrial matrix (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,037,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477613,877,579 - 14,034,875 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mipep
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,037,610 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477613,877,579 - 14,034,875 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MIPEP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381323,730,189 - 23,889,400 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1323,730,189 - 23,889,400 (-)EnsemblGRCh38hg38GRCh38
GRCh371324,304,328 - 24,463,539 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361323,202,328 - 23,361,559 (-)NCBINCBI36Build 36hg18NCBI36
Build 341323,202,328 - 23,361,533NCBI
Celera135,366,999 - 5,526,241 (-)NCBICelera
Cytogenetic Map13q12.12NCBI
HuRef135,115,419 - 5,274,678 (-)NCBIHuRef
CHM1_11324,272,481 - 24,431,743 (-)NCBICHM1_1
T2T-CHM13v2.01322,936,639 - 23,095,878 (-)NCBIT2T-CHM13v2.0
Mipep
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391461,022,011 - 61,142,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1461,022,022 - 61,142,927 (+)EnsemblGRCm39 Ensembl
GRCm381460,784,562 - 60,905,481 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,784,573 - 60,905,478 (+)EnsemblGRCm38mm10GRCm38
MGSCv371461,403,403 - 61,522,450 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361459,738,692 - 59,859,588 (+)NCBIMGSCv36mm8
Celera1458,563,091 - 58,670,430 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1431.95NCBI
Mipep
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81539,102,301 - 39,227,915 (+)NCBIGRCr8
mRatBN7.21534,926,198 - 35,051,722 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,926,207 - 35,051,727 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1536,787,866 - 36,893,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,938,483 - 38,044,388 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01536,387,341 - 36,492,974 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01541,084,180 - 41,192,621 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1541,084,206 - 41,190,005 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01544,896,328 - 45,002,041 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41539,871,329 - 39,990,743 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11539,887,028 - 40,006,443 (+)NCBI
Celera1534,627,565 - 34,731,545 (+)NCBICelera
Cytogenetic Map15p12NCBI
Mipep
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554974,062,677 - 4,196,889 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554974,065,090 - 4,196,999 (-)NCBIChiLan1.0ChiLan1.0
MIPEP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21423,344,721 - 23,512,342 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11314,451,978 - 14,624,321 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0135,040,237 - 5,207,674 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11323,334,266 - 23,500,582 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1323,334,267 - 23,500,582 (-)Ensemblpanpan1.1panPan2
MIPEP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12514,755,474 - 14,930,412 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2514,753,596 - 14,930,369 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2514,833,115 - 15,007,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02514,886,171 - 15,060,823 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2514,886,180 - 15,062,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12514,767,513 - 14,942,058 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02514,770,383 - 14,944,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02514,818,700 - 14,993,399 (+)NCBIUU_Cfam_GSD_1.0
Mipep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945116,980,530 - 117,124,623 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366881,592,821 - 1,737,282 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366881,592,810 - 1,736,896 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MIPEP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl112,670,000 - 2,790,727 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1112,675,604 - 2,790,760 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,039,126 - 2,144,089 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MIPEP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.133,578,057 - 3,726,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl33,578,193 - 3,726,746 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605740,804,644 - 41,015,711 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004854841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004854842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021236355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01054944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01054951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01006727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH166109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000010251   ⟹   ENSHGLP00000010137
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,037,610 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000010252   ⟹   ENSHGLP00000010138
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477613,880,417 - 14,034,706 (+)Ensembl
RefSeq Acc Id: XM_004854841   ⟹   XP_004854898
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,880,417 - 14,034,875 (+)NCBI
RefSeq Acc Id: XM_004854842   ⟹   XP_004854899
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,880,290 - 13,976,138 (+)NCBI
RefSeq Acc Id: XM_021236352   ⟹   XP_021092011
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,880,290 - 14,016,565 (+)NCBI
RefSeq Acc Id: XM_021236353   ⟹   XP_021092012
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,880,290 - 13,976,138 (+)NCBI
RefSeq Acc Id: XM_021236354   ⟹   XP_021092013
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,880,428 - 14,034,875 (+)NCBI
RefSeq Acc Id: XM_021236355   ⟹   XP_021092014
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477613,877,579 - 14,034,875 (+)NCBI
RefSeq Acc Id: XP_021092014   ⟸   XM_021236355
- Peptide Label: isoform X5
- UniProtKB: A0AAX6R5S2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092011   ⟸   XM_021236352
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R543 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004854899   ⟸   XM_004854842
- Peptide Label: isoform X4
- UniProtKB: A0AAX6PM06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092012   ⟸   XM_021236353
- Peptide Label: isoform X3
- UniProtKB: A0AAX6R606 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004854898   ⟸   XM_004854841
- Peptide Label: isoform X1
- UniProtKB: G5AMY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092013   ⟸   XM_021236354
- Peptide Label: isoform X5
- UniProtKB: A0AAX6R5S2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010137   ⟸   ENSHGLT00000010251
Ensembl Acc Id: ENSHGLP00000010138   ⟸   ENSHGLT00000010252


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007271 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010251 ENTREZGENE
Gene3D-CATH 1.10.1370.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro M3A_MIP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Neurolysin/TOP_dom2 UniProtKB/TrEMBL
  Pept_M3A_M3B UniProtKB/TrEMBL
  Pept_M3A_M3B UniProtKB/TrEMBL
KEGG Report hgl:101696293 UniProtKB/TrEMBL
NCBI Gene Mipep ENTREZGENE
PANTHER MITOCHONDRIAL INTERMEDIATE PEPTIDASE UniProtKB/TrEMBL
  PTHR11804 UniProtKB/TrEMBL
Pfam Peptidase_M3 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
UniProt A0AAX6PM06 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R543 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R5S2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R606 ENTREZGENE, UniProtKB/TrEMBL
  G5AMY6 ENTREZGENE, UniProtKB/TrEMBL