Ints7 (integrator complex subunit 7) - Rat Genome Database

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Gene: Ints7 (integrator complex subunit 7) Heterocephalus glaber
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Symbol: Ints7
Name: integrator complex subunit 7
RGD ID: 18932250
Description: INVOLVED IN cellular response to ionizing radiation (ortholog); DNA damage checkpoint signaling (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); parathyroid carcinoma (ortholog); FOUND IN chromosome (ortholog); cytoplasm (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,524,459 - 17,612,131 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromosome  (ISO)
cytoplasm  (ISO)
integrator complex  (IEA)
nuclear body  (ISO)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Ints7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477117,524,459 - 17,612,131 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
INTS7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381211,940,403 - 212,035,557 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1211,940,399 - 212,035,557 (-)EnsemblGRCh38hg38GRCh38
GRCh371212,113,745 - 212,208,899 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,181,321 - 210,275,507 (-)NCBINCBI36Build 36hg18NCBI36
Celera1185,341,779 - 185,435,963 (-)NCBICelera
Cytogenetic Map1q32.3ENTREZGENE
HuRef1182,790,784 - 182,886,038 (-)NCBIHuRef
CHM1_11213,386,120 - 213,481,388 (-)NCBICHM1_1
T2T-CHM13v2.01211,186,567 - 211,281,644 (-)NCBIT2T-CHM13v2.0
Ints7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,307,652 - 191,355,802 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,307,748 - 191,355,800 (+)EnsemblGRCm39 Ensembl
GRCm381191,575,540 - 191,623,690 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,575,636 - 191,623,688 (+)EnsemblGRCm38mm10GRCm38
MGSCv371193,399,613 - 193,445,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,276,395 - 193,323,290 (+)NCBIMGSCv36mm8
Celera1198,526,378 - 198,572,332 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.51NCBI
Ints7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,686,208 - 105,739,609 (+)NCBIGRCr8
mRatBN7.213103,155,123 - 103,207,953 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13103,155,090 - 103,208,592 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13105,675,160 - 105,727,919 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013107,059,009 - 107,111,770 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,274,080 - 104,326,845 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,257,571 - 110,310,413 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,257,571 - 110,310,413 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,821,472 - 114,873,815 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,641,207 - 107,696,311 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113107,830,267 - 107,884,967 (+)NCBI
Celera13102,594,374 - 102,646,905 (+)NCBICelera
Cytogenetic Map13q27NCBI
Ints7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,299,697 - 5,371,896 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,299,696 - 5,371,496 (+)NCBIChiLan1.0ChiLan1.0
INTS7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,367,474 - 37,462,976 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,331,961 - 37,427,466 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,508,066 - 187,603,567 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,372,012 - 192,466,510 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,372,016 - 192,466,510 (-)Ensemblpanpan1.1panPan2
INTS7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,238,809 - 10,323,699 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,239,711 - 10,323,611 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha79,816,473 - 9,901,338 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.079,945,253 - 10,030,174 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl79,945,257 - 10,030,159 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.179,867,362 - 9,952,291 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.079,970,424 - 10,055,230 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0710,094,891 - 10,179,712 (-)NCBIUU_Cfam_GSD_1.0
Ints7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934464,149,514 - 64,216,110 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,389,728 - 1,457,042 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,389,728 - 1,456,397 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INTS7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,275,626 - 131,354,592 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,275,530 - 131,364,490 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,330,530 - 144,374,834 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INTS7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,485,353 - 17,573,178 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,485,316 - 17,574,144 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605518,008,259 - 18,096,226 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000007462   ⟹   ENSHGLP00000007377
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477117,524,459 - 17,612,131 (-)Ensembl
RefSeq Acc Id: XM_004853532   ⟹   XP_004853589
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBI
RefSeq Acc Id: XM_004853537   ⟹   XP_004853594
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBI
RefSeq Acc Id: XM_021265554   ⟹   XP_021121213
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBI
RefSeq Acc Id: XR_002397879
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477117,525,471 - 17,612,260 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004853589 (Get FASTA)   NCBI Sequence Viewer  
  XP_004853594 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121213 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB02126 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000007377
RefSeq Acc Id: XP_021121213   ⟸   XM_021265554
- Peptide Label: isoform X3
- UniProtKB: G5AYL5 (UniProtKB/TrEMBL),   A0AAX6TLC4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853594   ⟸   XM_004853537
- Peptide Label: isoform X2
- UniProtKB: G5AYL5 (UniProtKB/TrEMBL),   A0AAX6PJA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853589   ⟸   XM_004853532
- Peptide Label: isoform X1
- UniProtKB: G5AYL5 (UniProtKB/TrEMBL),   A0AAX6PL24 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000007377   ⟸   ENSHGLT00000007462


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000005372 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000007462 ENTREZGENE
InterPro ARM-type_fold UniProtKB/TrEMBL
  INTS7 UniProtKB/TrEMBL
  INTS7_C UniProtKB/TrEMBL
NCBI Gene Ints7 ENTREZGENE
PANTHER C1ORF73 PROTEIN UniProtKB/TrEMBL
  INTEGRATOR COMPLEX SUBUNIT 7 UniProtKB/TrEMBL
Pfam INTS7_C UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
UniProt A0AAX6PJA8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PL24 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TLC4 ENTREZGENE, UniProtKB/TrEMBL
  G5AYL5 ENTREZGENE, UniProtKB/TrEMBL