![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ints7 | Rat | 17beta-estradiol | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Estradiol results in increased expression of INTS7 mRNA | CTD | PMID:19167446 | Ints7 | Rat | 17beta-estradiol | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA | CTD | PMID:20823114 | Ints7 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Ints7 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ints7 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Ints7 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ints7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA | CTD | PMID:22298810 | Ints7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | INTS7 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA | CTD | PMID:22574217 | Ints7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ints7 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of INTS7 mRNA | CTD | PMID:21570461 | Ints7 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of INTS7 mRNA | CTD | PMID:30851411 | Ints7 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Ints7 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of INTS7 mRNA | CTD | PMID:18648102 | Ints7 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of INTS7 mRNA | CTD | PMID:24780913 and PMID:30047161 | Ints7 | Rat | all-trans-retinoic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of INTS7 mRNA | CTD | PMID:33167477 | Ints7 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of INTS7 mRNA | CTD | PMID:38685447 | Ints7 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of INTS7 mRNA | CTD | PMID:30047161 | Ints7 | Rat | antirheumatic drug | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of INTS7 mRNA | CTD | PMID:24449571 | Ints7 | Rat | benzo[a]pyrene | multiple interactions | ISO | Ints7 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to INTS7 promoter] | CTD | PMID:19654925 | Ints7 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Ints7 | Rat | benzo[e]pyrene | decreases methylation | ISO | INTS7 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of INTS7 intron | CTD | PMID:30157460 | Ints7 | Rat | bisphenol A | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of INTS7 mRNA | CTD | PMID:26063408 | Ints7 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of INTS7 mRNA | CTD | PMID:32145629 and PMID:34947998 | Ints7 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of INTS7 mRNA | CTD | PMID:25181051 | Ints7 | Rat | bucladesine | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA | CTD | PMID:20823114 | Ints7 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of INTS7 mRNA | CTD | PMID:19167457 | Ints7 | Rat | caffeine | decreases phosphorylation | ISO | INTS7 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of INTS7 protein | CTD | PMID:35688186 | Ints7 | Rat | carbon nanotube | increases expression | ISO | Ints7 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of INTS7 mRNA | CTD | PMID:25554681 | Ints7 | Rat | chlorpyrifos | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of INTS7 mRNA | CTD | PMID:37019170 | Ints7 | Rat | coumestrol | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of INTS7 mRNA | CTD | PMID:19167446 | Ints7 | Rat | coumestrol | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA | CTD | PMID:19167446 | Ints7 | Rat | crocidolite asbestos | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of INTS7 mRNA | CTD | PMID:29279043 | Ints7 | Rat | cyclosporin A | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of INTS7 mRNA | CTD | PMID:25562108 | Ints7 | Rat | diethyl maleate | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | diethyl maleate results in decreased expression of INTS7 mRNA | CTD | PMID:25270620 | Ints7 | Rat | dorsomorphin | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INTS7 mRNA | CTD | PMID:27188386 | Ints7 | Rat | doxorubicin | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of INTS7 mRNA | CTD | PMID:29803840 | Ints7 | Rat | epoxiconazole | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of INTS7 mRNA | CTD | PMID:35436446 | Ints7 | Rat | ethanol | affects expression | ISO | Ints7 (Mus musculus) | 6480464 | Ethanol affects the expression of INTS7 mRNA | CTD | PMID:30319688 | Ints7 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of INTS7 mRNA | CTD | PMID:30307764 | Ints7 | Rat | folic acid | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of INTS7 mRNA | CTD | PMID:25629700 | Ints7 | Rat | formaldehyde | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of INTS7 mRNA | CTD | PMID:23649840 | Ints7 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of INTS7 mRNA | CTD | PMID:33387578 | Ints7 | Rat | hypochlorous acid | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | Hypochlorous Acid results in decreased expression of INTS7 mRNA | CTD | PMID:19376150 | Ints7 | Rat | ivermectin | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of INTS7 protein | CTD | PMID:32959892 | Ints7 | Rat | medroxyprogesterone acetate | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of INTS7 mRNA | CTD | PMID:20823114 | Ints7 | Rat | methapyrilene | decreases methylation | ISO | INTS7 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of INTS7 intron | CTD | PMID:30157460 | Ints7 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of INTS7 mRNA | CTD | PMID:38685447 | Ints7 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of INTS7 mRNA | CTD | PMID:30047161 | Ints7 | Rat | methylmercury chloride | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of INTS7 mRNA | CTD | PMID:28001369 | Ints7 | Rat | nickel atom | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Nickel results in decreased expression of INTS7 mRNA | CTD | PMID:23195993 | Ints7 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA | CTD | PMID:25729387 | Ints7 | Rat | paracetamol | increases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of INTS7 mRNA | CTD | PMID:22230336 | Ints7 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of INTS7 mRNA | CTD | PMID:33387578 | Ints7 | Rat | PCB138 | multiple interactions | ISO | Ints7 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Ints7 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of INTS7 mRNA | CTD | PMID:25812627 | Ints7 | Rat | perfluorononanoic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of INTS7 mRNA | CTD | PMID:25812627 | Ints7 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of INTS7 mRNA | CTD | PMID:25812627 | Ints7 | Rat | perfluorooctanoic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of INTS7 mRNA | CTD | PMID:25812627 | Ints7 | Rat | rac-lactic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of INTS7 mRNA | CTD | PMID:30851411 | Ints7 | Rat | resveratrol | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of INTS7 mRNA | CTD | PMID:19167446 | Ints7 | Rat | resveratrol | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | resveratrol results in decreased expression of INTS7 protein | CTD | PMID:25505154 | Ints7 | Rat | SB 431542 | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INTS7 mRNA | CTD | PMID:27188386 | Ints7 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of INTS7 mRNA | CTD | PMID:19281266 | Ints7 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of INTS7 mRNA | CTD | PMID:30047161 | Ints7 | Rat | tert-butyl hydroperoxide | decreases methylation | ISO | INTS7 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased methylation of INTS7 gene | CTD | PMID:29432895 | Ints7 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of INTS7 mRNA | CTD | PMID:23411599 and PMID:34492290 | Ints7 | Rat | titanium dioxide | decreases methylation | ISO | Ints7 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of INTS7 gene | CTD | PMID:35295148 | Ints7 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of INTS7 mRNA | CTD | PMID:25729387 | Ints7 | Rat | trimellitic anhydride | increases expression | ISO | Ints7 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of INTS7 mRNA | CTD | PMID:19042947 | Ints7 | Rat | triphenyl phosphate | affects expression | ISO | INTS7 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of INTS7 mRNA | CTD | PMID:37042841 | Ints7 | Rat | triptonide | decreases expression | ISO | Ints7 (Mus musculus) | 6480464 | triptonide results in decreased expression of INTS7 mRNA | CTD | PMID:33045310 | Ints7 | Rat | valproic acid | decreases methylation | ISO | INTS7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of INTS7 gene | CTD | PMID:29154799 | Ints7 | Rat | valproic acid | affects expression | ISO | INTS7 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of INTS7 mRNA | CTD | PMID:25979313 | Ints7 | Rat | valproic acid | multiple interactions | ISO | INTS7 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of INTS7 mRNA | CTD | PMID:27188386 | Ints7 | Rat | valproic acid | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of INTS7 mRNA | CTD | PMID:23179753 more ... | Ints7 | Rat | vorinostat | decreases expression | ISO | INTS7 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of INTS7 mRNA | CTD | PMID:27188386 | |