Drp2 (dystrophin related protein 2) - Rat Genome Database

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Gene: Drp2 (dystrophin related protein 2) Heterocephalus glaber
Analyze
Symbol: Drp2
Name: dystrophin related protein 2
RGD ID: 18929464
Description: ENCODES a protein that exhibits zinc ion binding (inferred); INVOLVED IN synapse organization (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN dendrite (ortholog); glutamatergic synapse (ortholog); postsynaptic density (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Dystrophin-related protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,270,959 - 1,313,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,270,925 - 1,313,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Drp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,270,959 - 1,313,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,270,925 - 1,313,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,219,786 - 101,264,502 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX101,219,769 - 101,264,502 (+)EnsemblGRCh38hg38GRCh38
GRCh37X100,474,775 - 100,519,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,361,589 - 100,406,141 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X100,281,129 - 100,322,062NCBI
CeleraX100,993,699 - 101,038,255 (+)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,278,524 - 90,323,122 (+)NCBIHuRef
CHM1_1X100,368,768 - 100,413,292 (+)NCBICHM1_1
T2T-CHM13v2.0X99,663,879 - 99,708,607 (+)NCBIT2T-CHM13v2.0
Drp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,304,868 - 133,357,323 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,305,300 - 133,357,322 (+)EnsemblGRCm39 Ensembl
GRCm38X134,404,124 - 134,456,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,404,551 - 134,456,573 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X130,939,319 - 130,991,112 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,751,187 - 129,799,749 (+)NCBIMGSCv36mm8
CeleraX117,283,306 - 117,335,077 (+)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX56.18NCBI
Drp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,900,743 - 101,951,403 (+)NCBIGRCr8
mRatBN7.2X97,607,577 - 97,658,117 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,607,719 - 97,655,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,281,859 - 99,332,337 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,792,355 - 102,842,735 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X100,295,104 - 100,345,494 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X105,239,623 - 105,290,233 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,239,620 - 105,289,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,130,982 - 105,180,671 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,881,801 - 121,929,386 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X121,955,233 - 122,002,819 (+)NCBI
CeleraX98,649,223 - 98,695,429 (+)NCBICelera
Cytogenetic MapXq32NCBI
Drp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555037,383,567 - 7,426,124 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555037,383,567 - 7,423,489 (+)NCBIChiLan1.0ChiLan1.0
DRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,819,218 - 100,931,427 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,822,829 - 100,925,471 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,422,483 - 90,467,610 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,558,208 - 100,603,233 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,558,208 - 100,603,233 (+)Ensemblpanpan1.1panPan2
DRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,171,816 - 75,217,777 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,171,507 - 75,212,782 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,588,154 - 76,633,108 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,588,046 - 76,633,091 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,156,377 - 74,201,284 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,816,777 - 75,861,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,579,140 - 75,624,073 (+)NCBIUU_Cfam_GSD_1.0
Drp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,141,168 - 63,182,860 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936813292,396 - 334,020 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936813292,408 - 334,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,872,197 - 82,925,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,871,901 - 82,925,889 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,904,317 - 90,958,270 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,561,207 - 89,606,402 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,573,770 - 89,602,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,478,022 - 14,522,489 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003286   ⟹   ENSHGLP00000003231
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249021,270,959 - 1,313,097 (-)Ensembl
RefSeq Acc Id: XM_004872576   ⟹   XP_004872633
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,270,926 - 1,313,121 (-)NCBI
RefSeq Acc Id: XM_013068430   ⟹   XP_012923884
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,270,926 - 1,305,122 (-)NCBI
RefSeq Acc Id: XM_021250465   ⟹   XP_021106124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,270,925 - 1,313,122 (-)NCBI
RefSeq Acc Id: XM_021250466   ⟹   XP_021106125
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,270,926 - 1,305,062 (-)NCBI
RefSeq Acc Id: XM_021250467   ⟹   XP_021106126
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,270,925 - 1,305,067 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004872633 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923884 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106124 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106125 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106126 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15834 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003231
GenBank Protein JAO00175 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021106124   ⟸   XM_021250465
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SCD0 (UniProtKB/TrEMBL),   G5C2S3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106126   ⟸   XM_021250467
- Peptide Label: isoform X4
- UniProtKB: A0AAX6S9X4 (UniProtKB/TrEMBL),   G5C2S3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872633   ⟸   XM_004872576
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JH55 (UniProtKB/TrEMBL),   G5C2S3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923884   ⟸   XM_013068430
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SAF7 (UniProtKB/TrEMBL),   G5C2S3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106125   ⟸   XM_021250466
- Peptide Label: isoform X3
- UniProtKB: A0AAX6SAF7 (UniProtKB/TrEMBL),   G5C2S3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003231   ⟸   ENSHGLT00000003286


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002400 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000003286 ENTREZGENE
Gene3D-CATH 1.20.58.60 UniProtKB/TrEMBL
  2.20.70.10 UniProtKB/TrEMBL
  3.30.60.90 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF-hand_dom_typ1 UniProtKB/TrEMBL
  EF-hand_dom_typ2 UniProtKB/TrEMBL
  KCMF1/Dystrophin UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  Znf_ZZ UniProtKB/TrEMBL
  Znf_ZZ_sf UniProtKB/TrEMBL
KEGG Report hgl:101716635 UniProtKB/TrEMBL
NCBI Gene Drp2 ENTREZGENE
PANTHER DYSTROPHIN-RELATED PROTEIN 2 UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE KCMF1 UniProtKB/TrEMBL
Pfam EF-hand_2 UniProtKB/TrEMBL
  EF-hand_3 UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
  PF00569 UniProtKB/TrEMBL
  Spectrin UniProtKB/TrEMBL
PROSITE WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
  ZF_ZZ_1 UniProtKB/TrEMBL
  ZF_ZZ_2 UniProtKB/TrEMBL
SMART SM00456 UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
  ZnF_ZZ UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  Spectrin repeat UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF51045 UniProtKB/TrEMBL
UniProt A0A0P6JH55 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S9X4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SAF7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SCD0 ENTREZGENE, UniProtKB/TrEMBL
  G5C2S3 ENTREZGENE, UniProtKB/TrEMBL