Drp2 (dystrophin related protein 2) - Rat Genome Database

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Gene: Drp2 (dystrophin related protein 2) Rattus norvegicus
Analyze
Symbol: Drp2
Name: dystrophin related protein 2
RGD ID: 621750
Description: Predicted to enable zinc ion binding activity. Involved in synapse organization. Located in dendrite and membrane. Is active in glutamatergic synapse and postsynaptic density. Orthologous to human DRP2 (dystrophin related protein 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DRP-2; dystrophin-related protein 2; dystrophin-related protein 2 A-form; dystrophin-related protein 2 A-form splice variant
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X97,607,577 - 97,658,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,607,719 - 97,655,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,281,859 - 99,332,337 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X102,792,355 - 102,842,735 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X100,295,104 - 100,345,494 (+)NCBIRnor_WKY
Rnor_6.0X105,239,623 - 105,290,233 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,239,620 - 105,289,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,130,982 - 105,180,671 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,881,801 - 121,929,386 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X121,955,233 - 122,002,819 (+)NCBI
CeleraX98,649,223 - 98,695,429 (+)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Association of dystrophin-related protein 2 (DRP2) with postsynaptic densities in rat brain. Roberts RG and Sheng M, Mol Cell Neurosci 2000 Nov;16(5):674-85.
Additional References at PubMed
PMID:11430802   PMID:17873297   PMID:20131911   PMID:29339092  


Genomics

Comparative Map Data
Drp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X97,607,577 - 97,658,115 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,607,719 - 97,655,684 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX99,281,859 - 99,332,337 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0X102,792,355 - 102,842,735 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0X100,295,104 - 100,345,494 (+)NCBIRnor_WKY
Rnor_6.0X105,239,623 - 105,290,233 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX105,239,620 - 105,289,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,130,982 - 105,180,671 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X121,881,801 - 121,929,386 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X121,955,233 - 122,002,819 (+)NCBI
CeleraX98,649,223 - 98,695,429 (+)NCBICelera
Cytogenetic MapXq32NCBI
DRP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X101,219,786 - 101,264,502 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 EnsemblX101,219,769 - 101,264,502 (+)EnsemblGRCh38hg38GRCh38
GRCh37X100,474,775 - 100,519,491 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X100,361,589 - 100,406,141 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X100,281,129 - 100,322,062NCBI
CeleraX100,993,699 - 101,038,255 (+)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX90,278,524 - 90,323,122 (+)NCBIHuRef
CHM1_1X100,368,768 - 100,413,292 (+)NCBICHM1_1
T2T-CHM13v2.0X99,663,879 - 99,708,607 (+)NCBIT2T-CHM13v2.0
Drp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X133,304,873 - 133,357,323 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX133,305,300 - 133,357,322 (+)EnsemblGRCm39 Ensembl
GRCm38X134,404,124 - 134,456,574 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,404,551 - 134,456,573 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X130,939,319 - 130,991,112 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,751,187 - 129,799,749 (+)NCBIMGSCv36mm8
CeleraX117,283,306 - 117,335,077 (+)NCBICelera
Cytogenetic MapXE3NCBI
Drp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555037,383,567 - 7,426,124 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555037,383,567 - 7,423,489 (+)NCBIChiLan1.0ChiLan1.0
DRP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X100,558,208 - 100,603,233 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,558,208 - 100,603,233 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X90,422,483 - 90,467,610 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DRP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X75,171,816 - 75,217,777 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX75,171,507 - 75,212,782 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,588,154 - 76,633,108 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,588,046 - 76,633,091 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X74,156,377 - 74,201,284 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,816,777 - 75,861,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,579,140 - 75,624,073 (+)NCBIUU_Cfam_GSD_1.0
Drp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,141,168 - 63,182,860 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936813292,408 - 334,079 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,872,197 - 82,925,883 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,871,901 - 82,925,889 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,904,317 - 90,958,270 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DRP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,561,207 - 89,606,402 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,573,770 - 89,602,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,478,022 - 14,522,489 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249021,270,959 - 1,313,097 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249021,270,925 - 1,313,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
BI289865  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X97,651,394 - 97,651,550 (+)MAPPERmRatBN7.2
Rnor_6.0X105,283,511 - 105,283,666NCBIRnor6.0
Rnor_5.0X105,174,402 - 105,174,557UniSTSRnor5.0
RGSC_v3.4X121,926,845 - 121,927,000UniSTSRGSC3.4
CeleraX98,692,888 - 98,693,043UniSTS
RH 3.4 Map1943.31UniSTS
Cytogenetic MapXq34UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:53
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000039864
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 64 6 1
Low 2 12 4 12 4 8 10 10 20 35 10 8
Below cutoff 3 41 17 10 7 10 1 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000039864   ⟹   ENSRNOP00000037371
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,607,719 - 97,655,684 (+)Ensembl
Rnor_6.0 EnsemblX105,239,840 - 105,286,052 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085693   ⟹   ENSRNOP00000070220
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX97,628,525 - 97,655,684 (+)Ensembl
Rnor_6.0 EnsemblX105,239,620 - 105,289,808 (+)Ensembl
RefSeq Acc Id: NM_023971   ⟹   NP_076461
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X97,607,719 - 97,653,936 (+)NCBI
Rnor_6.0X105,239,840 - 105,286,052 (+)NCBI
Rnor_5.0X105,130,982 - 105,180,671 (+)NCBI
RGSC_v3.4X121,881,801 - 121,929,386 (+)RGD
CeleraX98,649,223 - 98,695,429 (+)RGD
Sequence:
RefSeq Acc Id: XM_008773433   ⟹   XP_008771655
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X97,607,577 - 97,658,115 (+)NCBI
Rnor_6.0X105,239,623 - 105,290,233 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008773436   ⟹   XP_008771658
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X97,626,807 - 97,658,115 (+)NCBI
Rnor_6.0X105,258,942 - 105,290,233 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039100043   ⟹   XP_038955971
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X97,607,968 - 97,658,115 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_076461   ⟸   NM_023971
- UniProtKB: G3V971 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008771655   ⟸   XM_008773433
- Peptide Label: isoform X1
- UniProtKB: G3V971 (UniProtKB/Swiss-Prot),   Q9EPA0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008771658   ⟸   XM_008773436
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000070220   ⟸   ENSRNOT00000085693
RefSeq Acc Id: ENSRNOP00000037371   ⟸   ENSRNOT00000039864
RefSeq Acc Id: XP_038955971   ⟸   XM_039100043
- Peptide Label: isoform X1
Protein Domains
WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9EPA0-F1-model_v2 AlphaFold Q9EPA0 1-957 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621750 AgrOrtholog
BioCyc Gene G2FUF-1688 BioCyc
Ensembl Genes ENSRNOG00000026704 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000037371 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000070220 ENTREZGENE
  ENSRNOP00000070220.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039864 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000085693 ENTREZGENE
  ENSRNOT00000085693.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.60.90 UniProtKB/Swiss-Prot
InterPro Dystrophin-related_2 UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF-hand_dom_typ1 UniProtKB/Swiss-Prot
  EF-hand_dom_typ2 UniProtKB/Swiss-Prot
  Spectrin/alpha-actinin UniProtKB/Swiss-Prot
  Spectrin_repeat UniProtKB/Swiss-Prot
  WW_dom UniProtKB/Swiss-Prot
  WW_dom_sf UniProtKB/Swiss-Prot
  Znf_ZZ UniProtKB/Swiss-Prot
  Znf_ZZ_sf UniProtKB/Swiss-Prot
KEGG Report rno:66027 UniProtKB/Swiss-Prot
NCBI Gene 66027 ENTREZGENE
Pfam EF-hand_2 UniProtKB/Swiss-Prot
  EF-hand_3 UniProtKB/Swiss-Prot
  PF00397 UniProtKB/Swiss-Prot
  PF00569 UniProtKB/Swiss-Prot
  Spectrin UniProtKB/Swiss-Prot
PhenoGen Drp2 PhenoGen
PIRSF Dystrophin-related_p2 UniProtKB/Swiss-Prot
PROSITE WW_DOMAIN_1 UniProtKB/Swiss-Prot
  WW_DOMAIN_2 UniProtKB/Swiss-Prot
  ZF_ZZ_1 UniProtKB/Swiss-Prot
  ZF_ZZ_2 UniProtKB/Swiss-Prot
SMART SM00456 UniProtKB/Swiss-Prot
  SPEC UniProtKB/Swiss-Prot
  ZnF_ZZ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
  SSF51045 UniProtKB/Swiss-Prot
UniProt A0A8L2R2Z3_RAT UniProtKB/TrEMBL
  DRP2_RAT UniProtKB/Swiss-Prot
  G3V971 ENTREZGENE
  Q9EPA0 ENTREZGENE
  Q9ES99_RAT UniProtKB/TrEMBL
UniProt Secondary G3V971 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Drp2  dystrophin related protein 2    dystrophin-related protein 2 A-form splice variant  Name updated 1299863 APPROVED
2002-08-07 Drp2  dystrophin-related protein 2 A-form splice variant      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization associated with brain membrane fractions and highly enriched in the postsynaptic density 632604
gene_expression expression larely confined to the vertebrate central nervous system 632604