Klhl4 (kelch like family member 4) - Rat Genome Database

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Gene: Klhl4 (kelch like family member 4) Heterocephalus glaber
Analyze
Symbol: Klhl4
Name: kelch like family member 4
RGD ID: 18929376
Description: ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); factor VIII deficiency (ortholog); FOUND IN centriolar satellite (ortholog); microtubule cytoskeleton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Kelch-like protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624852493,040 - 629,663 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624852493,062 - 629,787 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Klhl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624852493,040 - 629,663 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624852493,062 - 629,787 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KLHL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X87,517,802 - 87,670,050 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX87,517,409 - 87,670,050 (+)EnsemblGRCh38hg38GRCh38
GRCh37X86,772,805 - 86,925,050 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X86,659,465 - 86,811,706 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X86,578,961 - 86,730,741NCBI
CeleraX87,012,392 - 87,164,729 (+)NCBICelera
Cytogenetic MapXq21.31NCBI
HuRefX80,353,756 - 80,506,308 (+)NCBIHuRef
CHM1_1X86,665,377 - 86,817,732 (+)NCBICHM1_1
T2T-CHM13v2.0X85,944,797 - 86,097,065 (+)NCBIT2T-CHM13v2.0
Klhl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X113,384,030 - 113,470,826 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX113,384,030 - 113,470,526 (+)EnsemblGRCm39 Ensembl
GRCm38X114,474,333 - 114,561,129 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX114,474,333 - 114,560,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X111,588,129 - 111,674,307 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X110,591,464 - 110,677,642 (+)NCBIMGSCv36mm8
CeleraX101,283,043 - 101,355,844 (+)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX49.47NCBI
Klhl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X83,626,047 - 83,916,328 (+)NCBIGRCr8
mRatBN7.2X79,429,193 - 79,719,482 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX79,622,113 - 79,719,480 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX81,310,098 - 81,407,006 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X84,708,360 - 84,805,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X82,296,515 - 82,393,646 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X86,125,929 - 86,229,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX86,126,157 - 86,229,563 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X86,066,906 - 86,171,225 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X103,218,938 - 103,317,748 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX80,890,575 - 80,987,712 (+)NCBICelera
Cytogenetic MapXq31NCBI
Klhl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555251,849,413 - 1,965,441 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555251,849,428 - 1,963,168 (+)NCBIChiLan1.0ChiLan1.0
KLHL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X86,985,286 - 87,136,205 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X86,988,893 - 87,139,812 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X76,575,811 - 76,726,687 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X86,678,423 - 86,828,738 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX86,678,164 - 86,829,346 (+)Ensemblpanpan1.1panPan2
KLHL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X67,949,674 - 68,111,260 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX67,949,034 - 68,109,486 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX58,721,143 - 58,882,528 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X69,291,043 - 69,450,378 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX69,291,089 - 69,448,604 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X66,926,923 - 67,088,348 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X68,569,225 - 68,730,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X68,163,017 - 68,324,360 (+)NCBIUU_Cfam_GSD_1.0
Klhl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X76,323,006 - 76,422,124 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649911,235,788 - 11,334,958 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649911,235,844 - 11,335,678 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX70,334,774 - 70,435,109 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X70,334,755 - 70,436,299 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X80,884,832 - 81,030,921 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X76,157,121 - 76,316,371 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX76,157,130 - 76,314,932 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660674,434,150 - 4,594,245 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000003491   ⟹   ENSHGLP00000003436
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624852493,040 - 629,663 (-)Ensembl
RefSeq Acc Id: XM_004868868   ⟹   XP_004868925
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624852493,062 - 629,787 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004868925 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003436
  ENSHGLP00100006495
GenBank Protein JAN96527 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004868925   ⟸   XM_004868868
- UniProtKB: A0A0P6K1G1 (UniProtKB/TrEMBL),   G5BKI8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000003436   ⟸   ENSHGLT00000003491


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002543 Ensembl, ENTREZGENE
  ENSHGLG00100004868 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003491 ENTREZGENE
  ENSHGLT00100006582 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
  2.130.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  Gal_Oxidase_central_sf UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
KEGG Report hgl:101726511 UniProtKB/TrEMBL
NCBI Gene Klhl4 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  KELCH-LIKE PROTEIN 4 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt A0A0P6K1G1 ENTREZGENE, UniProtKB/TrEMBL
  G5BKI8 ENTREZGENE, UniProtKB/TrEMBL