Gpsm1 (G protein signaling modulator 1) - Rat Genome Database

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Gene: Gpsm1 (G protein signaling modulator 1) Heterocephalus glaber
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Symbol: Gpsm1
Name: G protein signaling modulator 1
RGD ID: 18927994
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (ortholog); INVOLVED IN negative regulation of GTPase activity (ortholog); negative regulation of guanyl-nucleotide exchange factor activity (ortholog); positive regulation of macroautophagy (ortholog); ASSOCIATED WITH Adams-Oliver Syndrome 5 (ortholog); autosomal dominant intellectual developmental disorder 8 (ortholog); autosomal dominant nocturnal frontal lobe epilepsy 5 (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); Golgi apparatus (ortholog); Golgi membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: G-protein-signaling modulator 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,507,242 - 1,529,163 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,507,255 - 1,529,170 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Gpsm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247601,507,242 - 1,529,163 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247601,507,255 - 1,529,170 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
GPSM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389136,327,539 - 136,359,601 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9136,327,476 - 136,359,605 (+)EnsemblGRCh38hg38GRCh38
GRCh379139,221,995 - 139,254,053 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369138,348,726 - 138,372,493 (+)NCBINCBI36Build 36hg18NCBI36
Build 349136,504,741 - 136,528,509NCBI
Celera9109,736,118 - 109,768,993 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9108,681,506 - 108,713,413 (+)NCBIHuRef
CHM1_19139,370,654 - 139,402,253 (+)NCBICHM1_1
T2T-CHM13v2.09148,556,955 - 148,588,936 (+)NCBIT2T-CHM13v2.0
Gpsm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39226,204,623 - 26,238,249 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl226,205,527 - 26,238,249 (+)EnsemblGRCm39 Ensembl
GRCm38226,314,611 - 26,348,237 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl226,315,515 - 26,348,237 (+)EnsemblGRCm38mm10GRCm38
MGSCv37226,171,060 - 26,203,755 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36226,137,549 - 26,170,244 (+)NCBIMGSCv36mm8
Celera226,038,151 - 26,065,930 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map218.73NCBI
Gpsm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8329,538,929 - 29,565,921 (+)NCBIGRCr8
mRatBN7.239,140,816 - 9,167,828 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl39,128,636 - 9,167,827 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx312,194,280 - 12,221,191 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0320,777,510 - 20,804,421 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0319,032,845 - 19,059,758 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.033,767,394 - 3,794,360 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl33,767,394 - 3,794,359 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.039,127,874 - 9,155,507 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.434,493,828 - 4,520,795 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.134,500,900 - 4,519,959 (+)NCBI
Celera33,960,926 - 3,987,743 (+)NCBICelera
Cytogenetic Map3p13NCBI
Gpsm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555134,361,139 - 4,387,356 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555134,363,534 - 4,387,356 (-)NCBIChiLan1.0ChiLan1.0
GPSM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2113,026,987 - 3,058,273 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan193,029,322 - 3,060,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09107,400,819 - 107,432,165 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19136,387,430 - 136,411,951 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9136,383,929 - 136,410,561 (+)Ensemblpanpan1.1panPan2
GPSM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1949,124,828 - 49,152,079 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl949,118,627 - 49,152,208 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha948,375,389 - 48,402,483 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0950,001,466 - 50,028,600 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl950,001,472 - 50,028,791 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1948,781,935 - 48,809,055 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0949,076,267 - 49,103,397 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0949,123,796 - 49,150,891 (-)NCBIUU_Cfam_GSD_1.0
Gpsm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947201,905,770 - 201,932,514 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366691,440,902 - 1,463,944 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366691,442,550 - 1,469,563 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPSM1
(Sus scrofa - pig)		 No map positions available.
GPSM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,845,882 - 1,877,400 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,847,233 - 1,877,265 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660583,338,671 - 3,370,250 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000017711   ⟹   ENSHGLP00000017536
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247601,507,242 - 1,529,163 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000017712   ⟹   ENSHGLP00000017537
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247601,507,358 - 1,528,106 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000017713   ⟹   ENSHGLP00000017538
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247601,511,357 - 1,528,106 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000017714   ⟹   ENSHGLP00000017539
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247601,519,001 - 1,528,106 (+)Ensembl
RefSeq Acc Id: XM_004848893   ⟹   XP_004848950
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247601,507,255 - 1,529,170 (+)NCBI
RefSeq Acc Id: XM_004848894   ⟹   XP_004848951
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247601,510,595 - 1,529,170 (+)NCBI
RefSeq Acc Id: XM_004848896   ⟹   XP_004848953
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247601,518,917 - 1,529,170 (+)NCBI
RefSeq Acc Id: XM_004848898   ⟹   XP_004848955
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247601,522,952 - 1,529,170 (+)NCBI
RefSeq Acc Id: XM_004848899   ⟹   XP_004848956
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247601,523,689 - 1,529,170 (+)NCBI
RefSeq Acc Id: XP_004848950   ⟸   XM_004848893
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JCB0 (UniProtKB/TrEMBL),   G5B6B7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848951   ⟸   XM_004848894
- Peptide Label: isoform X4
- UniProtKB: G5B6B7 (UniProtKB/TrEMBL),   A0AAX6PCP1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848953   ⟸   XM_004848896
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PD77 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848955   ⟸   XM_004848898
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PD04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848956   ⟸   XM_004848899
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PD04 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000017539   ⟸   ENSHGLT00000017714
Ensembl Acc Id: ENSHGLP00000017536   ⟸   ENSHGLT00000017711
Ensembl Acc Id: ENSHGLP00000017538   ⟸   ENSHGLT00000017713
Ensembl Acc Id: ENSHGLP00000017537   ⟸   ENSHGLT00000017712


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012552 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017711 ENTREZGENE
  ENSHGLT00000017713 ENTREZGENE
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro GoLoco_motif UniProtKB/TrEMBL
  GPSM UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
KEGG Report hgl:101724892 UniProtKB/TrEMBL
NCBI Gene Gpsm1 ENTREZGENE
PANTHER G-PROTEIN-SIGNALING MODULATOR 1 UniProtKB/TrEMBL
  LD33695P UniProtKB/TrEMBL
Pfam GoLoco UniProtKB/TrEMBL
  TPR_10 UniProtKB/TrEMBL
  TPR_12 UniProtKB/TrEMBL
PROSITE GOLOCO UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
SMART GoLoco UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0P6JCB0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PCP1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PD04 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PD77 ENTREZGENE, UniProtKB/TrEMBL
  G5B6B7 ENTREZGENE, UniProtKB/TrEMBL