Foxj2 (forkhead box J2) - Rat Genome Database

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Gene: Foxj2 (forkhead box J2) Heterocephalus glaber
Analyze
Symbol: Foxj2
Name: forkhead box J2
RGD ID: 18927176
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN male meiosis I (ortholog); negative regulation of angiogenesis (ortholog); negative regulation of blood vessel endothelial cell differentiation (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 21 (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); Klippel-Feil syndrome 3 (ortholog); FOUND IN fibrillar center (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein J2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248605,176,257 - 5,195,682 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248605,176,301 - 5,195,715 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Foxj2Naked Mole-Ratdevelopmental and epileptic encephalopathy 21  ISORGD:13449048554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy, 21ClinVarPMID:18712838|PMID:21031596|PMID:24399846|PMID:28492532|PMID:30626896
Foxj2Naked Mole-RatHyperphosphatemic Familial Tumoral Calcinosis 1  ISORGD:13449048554872ClinVar Annotator: match by term: Tumoral calcinosis, hyperphosphatemic, familial, 1ClinVarPMID:25378588|PMID:29389098
Foxj2Naked Mole-RatKlippel-Feil syndrome 3  ISORGD:13449048554872ClinVar Annotator: match by term: Klippel-Feil syndrome 3, autosomal dominantClinVarPMID:28492532
Foxj2Naked Mole-Ratlymphoproliferative syndrome 2  ISORGD:13449048554872ClinVar Annotator: match by term: Lymphoproliferative syndrome 2ClinVarPMID:28492532
Foxj2Naked Mole-Ratperoxisome biogenesis disorder 2B  ISORGD:13449048554872ClinVar Annotator: match by term: Peroxisome biogenesis disorder 2BClinVarPMID:18712838|PMID:21031596|PMID:24399846|PMID:28492532|PMID:30626896
Foxj2Naked Mole-RatTemtamy syndrome  ISORGD:13449048554872ClinVar Annotator: match by term: Temtamy syndromeClinVarPMID:28492532


Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Foxj2Naked Mole-Ratmale meiosis I involved_inISORGD:15573469068941 PMID:27316861UniProtPMID:27316861
Foxj2Naked Mole-Ratnegative regulation of angiogenesis involved_inISORGD:13449049068941 PMID:24792364BHF-UCLPMID:24792364
Foxj2Naked Mole-Ratnegative regulation of blood vessel endothelial cell differentiation involved_inISORGD:13449049068941 PMID:24792364BHF-UCLPMID:24792364
Foxj2Naked Mole-Ratpositive regulation of DNA-templated transcription involved_inISORGD:13449049068941 PMID:10777590, PMID:10966786UniProtPMID:10777590|PMID:10966786
Foxj2Naked Mole-Ratpositive regulation of transcription by RNA polymerase II involved_inISORGD:13449049068941 PMID:10777590NTNU_SBPMID:10777590
Foxj2Naked Mole-Ratpositive regulation of vascular associated smooth muscle cell proliferation involved_inISORGD:13449049068941 PMID:24792364BHF-UCLPMID:24792364
Foxj2Naked Mole-Ratregulation of DNA-templated transcription involved_inIEAInterPro:IPR001766|InterPro:IPR030456150520179 InterProGO_REF:0000002
Foxj2Naked Mole-Ratregulation of transcription by RNA polymerase II involved_inIEAPANTHER:PTN000215287150520179 TreeGrafterGO_REF:0000118
Foxj2Naked Mole-Ratspermatogenesis involved_inISORGD:15573469068941 PMID:27316861UniProtPMID:27316861
1 to 9 of 9 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Foxj2Naked Mole-Ratfibrillar center located_inISORGD:13449049068941 HPAGO_REF:0000052
Foxj2Naked Mole-Ratnucleoplasm located_inISORGD:13449049068941 HPAGO_REF:0000052
Foxj2Naked Mole-Ratnucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
Foxj2Naked Mole-Ratnucleus located_inIEAPANTHER:PTN000215287150520179 TreeGrafterGO_REF:0000118
Foxj2Naked Mole-Ratnucleus located_inIEAUniRule:UR000413741150520179 UniProtGO_REF:0000104
Foxj2Naked Mole-Ratnucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Foxj2Naked Mole-RatDNA binding enablesIEAUniRule:UR000413741150520179 UniProtGO_REF:0000104
Foxj2Naked Mole-RatDNA binding enablesIEAUniProtKB-KW:KW-0238150520179 UniProtGO_REF:0000043
Foxj2Naked Mole-RatDNA-binding transcription activator activity, RNA polymerase II-specific enablesISORGD:13449049068941 PMID:10777590NTNU_SBPMID:10777590
Foxj2Naked Mole-RatDNA-binding transcription factor activity enablesIEAInterPro:IPR001766|InterPro:IPR030456150520179 InterProGO_REF:0000002
Foxj2Naked Mole-RatDNA-binding transcription factor activity, RNA polymerase II-specific enablesIEAPANTHER:PTN000215287150520179 TreeGrafterGO_REF:0000118
Foxj2Naked Mole-Ratidentical protein binding enablesISOUniProtKB:Q9P0K89068941 PMID:25609649IntActPMID:25609649
Foxj2Naked Mole-Ratprotein binding enablesISOUniProtKB:Q9H0L4|UniProtKB:Q9H6Z99068941 PMID:32296183IntActPMID:32296183
Foxj2Naked Mole-Ratprotein binding enablesISOUniProtKB:Q9H6Z99068941 PMID:25416956IntActPMID:25416956
Foxj2Naked Mole-RatRNA polymerase II cis-regulatory region sequence-specific DNA binding enablesIEAPANTHER:PTN000215287150520179 TreeGrafterGO_REF:0000118
Foxj2Naked Mole-Ratsequence-specific DNA binding enablesIEAInterPro:IPR001766|InterPro:IPR030456150520179 InterProGO_REF:0000002
Foxj2Naked Mole-Ratsequence-specific double-stranded DNA binding enablesISORGD:13449049068941 PMID:28473536ARUK-UCLPMID:28473536
1 to 11 of 11 rows

PMID:30032202  



Foxj2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248605,176,257 - 5,195,682 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248605,176,301 - 5,195,715 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FOXJ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,032,716 - 8,055,517 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,032,716 - 8,055,517 (+)EnsemblGRCh38hg38GRCh38
GRCh37128,185,312 - 8,208,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,076,626 - 8,099,385 (+)NCBINCBI36Build 36hg18NCBI36
Build 34128,076,625 - 8,099,384NCBI
Celera129,762,431 - 9,785,190 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef127,996,913 - 8,019,846 (+)NCBIHuRef
CHM1_1128,184,575 - 8,207,342 (+)NCBICHM1_1
T2T-CHM13v2.0128,046,312 - 8,069,122 (+)NCBIT2T-CHM13v2.0
Foxj2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396122,797,143 - 122,822,325 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6122,796,873 - 122,822,325 (+)EnsemblGRCm39 Ensembl
GRCm386122,820,184 - 122,845,366 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6122,819,914 - 122,845,366 (+)EnsemblGRCm38mm10GRCm38
MGSCv376122,770,202 - 122,795,384 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366122,786,130 - 122,810,982 (+)NCBIMGSCv36mm8
Celera6124,622,347 - 124,647,534 (+)NCBICelera
Cytogenetic Map6F2NCBI
cM Map657.91NCBI
Foxj2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84157,718,990 - 157,745,468 (+)NCBIGRCr8
mRatBN7.24156,047,043 - 156,073,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4156,046,969 - 156,073,518 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4162,317,196 - 162,343,161 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04158,100,418 - 158,126,383 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04156,745,505 - 156,771,468 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04155,653,446 - 155,679,815 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4155,653,718 - 155,679,793 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04222,674,331 - 222,700,694 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44159,295,252 - 159,321,208 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4144,867,747 - 144,893,819 (+)NCBICelera
Cytogenetic Map4q42NCBI
Foxj2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554136,686,398 - 6,703,173 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554136,692,343 - 6,705,760 (+)NCBIChiLan1.0ChiLan1.0
FOXJ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21013,586,695 - 13,611,942 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11213,585,787 - 13,608,715 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,152,037 - 8,175,291 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,194,519 - 8,217,778 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,194,519 - 8,217,778 (+)Ensemblpanpan1.1panPan2
FOXJ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12737,412,148 - 37,430,861 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2737,411,358 - 37,428,887 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha279,185,094 - 9,204,722 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02737,765,223 - 37,784,865 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2737,765,255 - 37,784,853 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12737,640,826 - 37,659,521 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02737,681,129 - 37,700,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,671,639 - 8,691,483 (-)NCBIUU_Cfam_GSD_1.0
Foxj2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494599,140,505 - 99,158,922 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936892331,239 - 344,624 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936892324,103 - 344,739 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXJ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,061,978 - 63,085,037 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,061,978 - 63,087,689 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
FOXJ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,101,982 - 8,125,764 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,109,340 - 8,125,743 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666089195,607 - 219,438 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000002131   ⟹   ENSHGLP00000002083
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248605,176,257 - 5,195,682 (+)Ensembl
RefSeq Acc Id: XM_004869520   ⟹   XP_004869577
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248605,176,301 - 5,195,715 (+)NCBI
RefSeq Acc Id: XM_004869521   ⟹   XP_004869578
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248605,176,301 - 5,195,715 (+)NCBI
RefSeq Acc Id: XM_013067326   ⟹   XP_012922780
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248605,176,301 - 5,195,715 (+)NCBI
Protein RefSeqs XP_004869577 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869578 (Get FASTA)   NCBI Sequence Viewer  
  XP_012922780 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000002083
RefSeq Acc Id: XP_004869577   ⟸   XM_004869520
- Peptide Label: isoform X1
- UniProtKB: A0AAX6QBS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869578   ⟸   XM_004869521
- Peptide Label: isoform X2
- UniProtKB: A0AAX6QB58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012922780   ⟸   XM_013067326
- Peptide Label: isoform X3
- UniProtKB: A0AAX6QPG5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000002083   ⟸   ENSHGLT00000002131



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000001583 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000002131 ENTREZGENE
Gene3D-CATH Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain UniProtKB/TrEMBL
InterPro FH_FOXJ2 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOXJ2/3-like UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Foxj2 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN J2 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN J2 FAMILY MEMBER UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP Winged helix' DNA-binding domain UniProtKB/TrEMBL
UniProt A0AAX6QB58 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QBS7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QPG5 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows