Dync1li2 (dynein cytoplasmic 1 light intermediate chain 2) - Rat Genome Database

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Gene: Dync1li2 (dynein cytoplasmic 1 light intermediate chain 2) Heterocephalus glaber
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Symbol: Dync1li2
Name: dynein cytoplasmic 1 light intermediate chain 2
RGD ID: 18926722
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); centrosome localization (ortholog); microtubule cytoskeleton organization (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); cataract 5 multiple types (ortholog); Chromosome 16q12 Duplication Syndrome (ortholog); FOUND IN centrosome (ortholog); kinetochore (ortholog); late endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cytoplasmic dynein 1 light intermediate chain 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,728,018 - 19,750,640 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,727,861 - 19,752,220 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Dync1li2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,728,018 - 19,750,640 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,727,861 - 19,752,220 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DYNC1LI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381666,720,893 - 66,751,609 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1666,720,893 - 66,751,609 (-)EnsemblGRCh38hg38GRCh38
GRCh371666,754,796 - 66,785,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,312,300 - 65,343,026 (-)NCBINCBI36Build 36hg18NCBI36
Build 341665,312,299 - 65,343,026NCBI
Celera1651,262,971 - 51,293,905 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1652,629,870 - 52,660,679 (-)NCBIHuRef
CHM1_11668,161,883 - 68,192,604 (-)NCBICHM1_1
T2T-CHM13v2.01672,515,191 - 72,545,899 (-)NCBIT2T-CHM13v2.0
Dync1li2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,144,306 - 105,170,415 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,144,312 - 105,169,679 (-)EnsemblGRCm39 Ensembl
GRCm388104,417,674 - 104,443,050 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8104,417,680 - 104,443,047 (-)EnsemblGRCm38mm10GRCm38
MGSCv378106,941,574 - 106,966,947 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368107,308,253 - 107,332,134 (-)NCBIMGSCv36mm8
Celera8108,648,540 - 108,674,331 (-)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Dync1li2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr819538,207 - 561,110 (+)NCBIGRCr8
mRatBN7.219531,783 - 554,670 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl19531,812 - 554,670 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx19527,820 - 550,511 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0191,294,617 - 1,317,308 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.019569,831 - 592,522 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.019740,007 - 762,897 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl19740,028 - 762,897 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.019738,990 - 762,115 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.419469,163 - 510,647 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.119469,162 - 510,647 (+)NCBI
Celera19527,460 - 550,605 (+)NCBICelera
Cytogenetic Map19p14NCBI
Dync1li2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543323,262,981 - 23,287,067 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543323,262,981 - 23,286,506 (-)NCBIChiLan1.0ChiLan1.0
DYNC1LI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,223,554 - 76,254,408 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,135,962 - 82,166,761 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,038,975 - 47,069,849 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,141,323 - 66,170,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1666,141,323 - 66,170,693 (-)Ensemblpanpan1.1panPan2
DYNC1LI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,539,880 - 82,566,689 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,539,876 - 82,563,905 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,528,033 - 82,555,123 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,976,226 - 83,003,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,976,246 - 83,003,337 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,799,354 - 82,826,459 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,486,217 - 82,513,307 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0583,124,764 - 83,151,903 (+)NCBIUU_Cfam_GSD_1.0
Dync1li2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934942,552,874 - 42,576,200 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,012,832 - 17,036,392 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,012,911 - 17,036,290 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC1LI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,416,477 - 27,446,360 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,416,475 - 27,446,172 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DYNC1LI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1552,416,645 - 52,448,754 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl552,419,479 - 52,448,901 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604723,462,778 - 23,495,331 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024876   ⟹   ENSHGLP00000024654
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474619,728,018 - 19,750,640 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000024877   ⟹   ENSHGLP00000024655
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474619,728,048 - 19,748,958 (+)Ensembl
RefSeq Acc Id: XM_004843100   ⟹   XP_004843157
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474619,727,861 - 19,752,220 (+)NCBI
RefSeq Acc Id: XM_021256937   ⟹   XP_021112596
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474619,728,416 - 19,752,220 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004843157 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112596 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07331 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024654
GenBank Protein JAO02335 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004843157   ⟸   XM_004843100
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JFF4 (UniProtKB/TrEMBL),   G5BDH0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112596   ⟸   XM_021256937
- Peptide Label: isoform X2
- UniProtKB: G5BDH0 (UniProtKB/TrEMBL),   A0AAX6SW94 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024655   ⟸   ENSHGLT00000024877
Ensembl Acc Id: ENSHGLP00000024654   ⟸   ENSHGLT00000024876


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017579 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024876 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Dynein1_light_intermed_chain UniProtKB/TrEMBL
  Dynein_light_int_chain UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report hgl:101702724 UniProtKB/TrEMBL
NCBI Gene Dync1li2 ENTREZGENE
PANTHER CYTOPLASMIC DYNEIN 1 LIGHT INTERMEDIATE CHAIN 2 UniProtKB/TrEMBL
  PTHR12688 UniProtKB/TrEMBL
Pfam DLIC UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6JFF4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SW94 ENTREZGENE, UniProtKB/TrEMBL
  G5BDH0 ENTREZGENE, UniProtKB/TrEMBL