Dpysl3 (dihydropyrimidinase like 3) - Rat Genome Database

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Gene: Dpysl3 (dihydropyrimidinase like 3) Heterocephalus glaber
Analyze
Symbol: Dpysl3
Name: dihydropyrimidinase like 3
RGD ID: 18926422
Description: ENCODES a protein that exhibits chondroitin sulfate binding (ortholog); filamin binding (ortholog); identical protein binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); cellular response to cytokine stimulus (ortholog); negative regulation of cell migration (ortholog); ASSOCIATED WITH autistic disorder (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cell body (ortholog); exocytic vesicle (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Dihydropyrimidinase-related protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247746,835,299 - 6,943,552 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247746,836,198 - 6,943,528 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dpysl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247746,835,299 - 6,943,552 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247746,836,198 - 6,943,528 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DPYSL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385147,390,808 - 147,510,068 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5147,390,808 - 147,510,068 (-)EnsemblGRCh38hg38GRCh38
GRCh375146,770,371 - 146,889,631 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365146,750,564 - 146,813,453 (-)NCBINCBI36Build 36hg18NCBI36
Build 345146,750,565 - 146,813,453NCBI
Celera5142,852,394 - 142,915,278 (-)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5141,917,546 - 142,036,676 (-)NCBIHuRef
CHM1_15146,202,682 - 146,322,042 (-)NCBICHM1_1
T2T-CHM13v2.05147,926,586 - 148,045,847 (-)NCBIT2T-CHM13v2.0
Dpysl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391843,454,044 - 43,571,354 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1843,454,049 - 43,571,351 (-)EnsemblGRCm39 Ensembl
GRCm381843,320,979 - 43,438,286 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1843,320,984 - 43,438,286 (-)EnsemblGRCm38mm10GRCm38
MGSCv371843,483,881 - 43,552,985 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361843,449,613 - 43,518,664 (-)NCBIMGSCv36mm8
Celera1844,709,412 - 44,773,911 (-)NCBICelera
Cytogenetic Map18B3NCBI
Dpysl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81835,625,357 - 35,731,152 (-)NCBIGRCr8
mRatBN7.21835,374,427 - 35,480,228 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1835,377,181 - 35,480,157 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1835,478,465 - 35,584,254 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01836,196,778 - 36,302,565 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01835,573,728 - 35,679,526 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01837,716,371 - 37,819,347 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1837,716,143 - 37,819,097 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01837,372,407 - 37,475,307 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41836,620,669 - 36,680,355 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11836,655,934 - 36,715,621 (-)NCBI
Celera1834,966,806 - 35,026,066 (-)NCBICelera
Cytogenetic Map18p11-q11NCBI
Dpysl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554156,702,768 - 6,814,097 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554156,703,212 - 6,813,906 (+)NCBIChiLan1.0ChiLan1.0
DPYSL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24142,643,607 - 142,763,113 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15140,783,158 - 140,902,554 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05142,839,385 - 142,958,774 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15148,850,102 - 148,969,606 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5148,850,102 - 148,969,606 (-)Ensemblpanpan1.1panPan2
DPYSL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1241,687,725 - 41,809,402 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl241,690,845 - 41,802,376 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha238,729,489 - 38,849,072 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0242,142,973 - 42,262,444 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl242,142,980 - 42,263,107 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,218,903 - 39,339,535 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,029,019 - 40,148,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0240,851,053 - 40,970,669 (-)NCBIUU_Cfam_GSD_1.0
Dpysl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213145,687,381 - 145,794,511 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365047,261,524 - 7,365,168 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365047,261,334 - 7,365,828 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPYSL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2148,662,051 - 148,776,619 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12148,663,563 - 148,777,055 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22155,127,544 - 155,234,332 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPYSL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12349,941,799 - 50,060,696 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2349,945,023 - 50,060,392 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603427,706,225 - 27,824,724 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000018999   ⟹   ENSHGLP00000018811
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247746,835,299 - 6,943,552 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000019000   ⟹   ENSHGLP00000018812
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247746,835,299 - 6,892,057 (-)Ensembl
RefSeq Acc Id: XM_004854360   ⟹   XP_004854417
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247746,836,198 - 6,892,009 (-)NCBI
RefSeq Acc Id: XM_021266171   ⟹   XP_021121830
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247746,836,198 - 6,943,528 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854417 (Get FASTA)   NCBI Sequence Viewer  
  XP_021121830 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12581 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018811
  ENSHGLP00000018812
  ENSHGLP00100012969
GenBank Protein JAO01265 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021121830   ⟸   XM_021266171
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004854417   ⟸   XM_004854360
- Peptide Label: isoform X2
- UniProtKB: G5BTH0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018811   ⟸   ENSHGLT00000018999
Ensembl Acc Id: ENSHGLP00000018812   ⟸   ENSHGLT00000019000


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013479 Ensembl, ENTREZGENE
  ENSHGLG00100009606 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018999 ENTREZGENE
  ENSHGLT00000019000 ENTREZGENE
  ENSHGLT00100013118 UniProtKB/TrEMBL
Gene3D-CATH 2.30.40.10 UniProtKB/TrEMBL
  Metal-dependent hydrolases UniProtKB/TrEMBL
InterPro Amidohydro-rel UniProtKB/TrEMBL
  Hydantoinase/dihydroPyrase UniProtKB/TrEMBL
  Metal-dep_hydrolase_composite UniProtKB/TrEMBL
  Metal_Hydrolase UniProtKB/TrEMBL
  Metallo-dep_Hydrolases_sf UniProtKB/TrEMBL
KEGG Report hgl:101702923 UniProtKB/TrEMBL
NCBI Gene Dpysl3 ENTREZGENE
PANTHER HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER UniProtKB/TrEMBL
  PTHR11647:SF57 UniProtKB/TrEMBL
Pfam Amidohydro_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF51338 UniProtKB/TrEMBL
  SSF51556 UniProtKB/TrEMBL
UniProt G5BTH0 ENTREZGENE, UniProtKB/TrEMBL