Dnaaf4 (dynein axonemal assembly factor 4) - Rat Genome Database

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Gene: Dnaaf4 (dynein axonemal assembly factor 4) Heterocephalus glaber
Analyze
Symbol: Dnaaf4 (Ensembl: DYX1C1)
Name: dynein axonemal assembly factor 4
RGD ID: 18925621
Description: ENCODES a protein that exhibits nuclear estrogen receptor binding (inferred); INVOLVED IN determination of left/right symmetry (ortholog); epithelial cilium movement involved in extracellular fluid movement (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); dyslexia (ortholog); FOUND IN centrosome (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dyslexia susceptibility 1 candidate 1; dyslexia susceptibility 1 candidate 1 protein; dyslexia susceptibility 1 candidate gene 1 protein; dyslexia susceptibility 1 candidate gene 1 protein homolog; Dyslexia susceptibility 1 candidate gene 1 protein-like protein; Dyx1c1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247316,215,737 - 6,241,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247316,215,798 - 6,270,210 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dnaaf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247316,215,737 - 6,241,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247316,215,798 - 6,270,210 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DNAAF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381555,417,755 - 55,508,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1555,410,525 - 55,508,234 (-)EnsemblGRCh38hg38GRCh38
GRCh371555,709,953 - 55,800,432 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361553,497,245 - 53,587,724 (-)NCBINCBI36Build 36hg18NCBI36
Build 341553,509,797 - 53,587,724NCBI
Celera1532,598,522 - 32,689,024 (-)NCBICelera
Cytogenetic Map15q21.3NCBI
HuRef1532,534,595 - 32,624,730 (-)NCBIHuRef
CHM1_11555,828,490 - 55,918,875 (-)NCBICHM1_1
T2T-CHM13v2.01553,220,992 - 53,311,451 (-)NCBIT2T-CHM13v2.0
Dnaaf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39972,863,574 - 72,880,971 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl972,866,067 - 72,880,346 (+)EnsemblGRCm39 Ensembl
GRCm38972,957,372 - 72,973,689 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl972,958,785 - 72,973,064 (+)EnsemblGRCm38mm10GRCm38
MGSCv37972,806,592 - 72,820,874 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36972,755,972 - 72,770,196 (+)NCBIMGSCv36mm8
Celera970,144,716 - 70,159,026 (+)NCBICelera
Cytogenetic Map9DNCBI
cM Map940.08NCBI
Dnaaf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8882,577,044 - 82,601,653 (+)NCBIGRCr8
mRatBN7.2873,696,394 - 73,711,315 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl873,698,103 - 73,711,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx879,221,451 - 79,234,648 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0877,494,064 - 77,507,259 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0875,331,425 - 75,344,622 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0879,637,678 - 79,651,892 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl879,638,696 - 79,651,884 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0873,438,090 - 73,451,862 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4877,702,354 - 77,715,547 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera868,043,581 - 68,056,319 (-)NCBICelera
Cytogenetic Map8q24NCBI
Dnaaf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955409498,450 - 523,067 (+)NCBIChiLan1.0ChiLan1.0
DNAAF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21644,673,412 - 44,762,123 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11548,833,257 - 48,947,299 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01534,382,064 - 34,469,432 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11552,711,349 - 52,800,598 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1552,711,349 - 52,791,281 (-)Ensemblpanpan1.1panPan2
DNAAF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13020,778,497 - 20,871,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3020,815,775 - 20,871,220 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3020,761,481 - 20,835,741 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03020,946,345 - 21,021,204 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3020,965,025 - 21,021,128 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13020,889,909 - 20,964,372 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03020,974,146 - 21,048,301 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03021,105,811 - 21,180,367 (-)NCBIUU_Cfam_GSD_1.0
Dnaaf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864099,063,503 - 99,112,487 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647116,912,155 - 16,960,468 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647116,911,575 - 16,960,521 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAAF4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1116,332,630 - 116,430,984 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11116,331,217 - 116,431,673 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21128,818,968 - 128,896,973 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAAF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12627,946,092 - 28,024,495 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666048113,257,359 - 113,328,014 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004835352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004835353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_004835355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013074223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021260830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01003559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01003560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01003561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01003562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01003563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01004184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH168142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000022335   ⟹   ENSHGLP00000022124
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247316,215,737 - 6,241,793 (+)Ensembl
RefSeq Acc Id: XM_004835352   ⟹   XP_004835409
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,806 - 6,242,152 (+)NCBI
RefSeq Acc Id: XM_004835353   ⟹   XP_004835410
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,805 - 6,243,505 (+)NCBI
RefSeq Acc Id: XM_004835355   ⟹   XP_004835412
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,801 - 6,242,152 (+)NCBI
RefSeq Acc Id: XM_013074223   ⟹   XP_012929677
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,804 - 6,270,207 (+)NCBI
RefSeq Acc Id: XM_021260798   ⟹   XP_021116457
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,798 - 6,244,095 (+)NCBI
RefSeq Acc Id: XM_021260814   ⟹   XP_021116473
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,801 - 6,270,210 (+)NCBI
RefSeq Acc Id: XM_021260818   ⟹   XP_021116477
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,798 - 6,241,737 (+)NCBI
RefSeq Acc Id: XM_021260820   ⟹   XP_021116479
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,801 - 6,270,207 (+)NCBI
RefSeq Acc Id: XM_021260827   ⟹   XP_021116486
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,801 - 6,243,505 (+)NCBI
RefSeq Acc Id: XM_021260830   ⟹   XP_021116489
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247316,215,799 - 6,238,103 (+)NCBI
RefSeq Acc Id: XP_021116457   ⟸   XM_021260798
- Peptide Label: isoform X1
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116477   ⟸   XM_021260818
- Peptide Label: isoform X4
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116489   ⟸   XM_021260830
- Peptide Label: isoform X6
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116473   ⟸   XM_021260814
- Peptide Label: isoform X3
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116479   ⟸   XM_021260820
- Peptide Label: isoform X5
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021116486   ⟸   XM_021260827
- Peptide Label: isoform X5
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004835412   ⟸   XM_004835355
- Peptide Label: isoform X5
- UniProtKB: G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012929677   ⟸   XM_013074223
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J556 (UniProtKB/TrEMBL),   G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004835410   ⟸   XM_004835353
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J556 (UniProtKB/TrEMBL),   G5B2P9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004835409   ⟸   XM_004835352
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J556 (UniProtKB/TrEMBL),   G5B2P9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000022124   ⟸   ENSHGLT00000022335


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015787 Ensembl, ENTREZGENE
  ENSHGLG00100005037 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000022335 ENTREZGENE
  ENSHGLT00100006801 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.60.40.790 UniProtKB/TrEMBL
InterPro CS_dom UniProtKB/TrEMBL
  CS_DYX1C1 UniProtKB/TrEMBL
  Dynein_assembly_factor_4 UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
KEGG Report hgl:101716523 UniProtKB/TrEMBL
NCBI Gene Dnaaf4 ENTREZGENE
PANTHER DYNEIN ASSEMBLY FACTOR 4, AXONEMAL UniProtKB/TrEMBL
  DYNEIN AXONEMAL ASSEMBLY FACTOR 4 UniProtKB/TrEMBL
Pfam PF04969 UniProtKB/TrEMBL
PROSITE PS51203 UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
  SSF49764 UniProtKB/TrEMBL
UniProt A0A0P6J556 ENTREZGENE, UniProtKB/TrEMBL
  G5B2P9 ENTREZGENE, UniProtKB/TrEMBL