Srrm2 (serine/arginine repetitive matrix 2) - Rat Genome Database

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Gene: Srrm2 (serine/arginine repetitive matrix 2) Heterocephalus glaber
Analyze
Symbol: Srrm2
Name: serine/arginine repetitive matrix 2
RGD ID: 18924637
Description: ENCODES a protein that exhibits C2H2 zinc finger domain binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH Autosomal Dominant Intellectual Developmental Disorder 72 (ortholog); developmental and epileptic encephalopathy 1 (ortholog); epilepsy (ortholog); FOUND IN Cajal body (ortholog); catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/arginine repetitive matrix protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824594,790 - 609,750 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824594,203 - 613,225 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Srrm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824594,790 - 609,750 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824594,203 - 613,225 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SRRM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,752,638 - 2,771,412 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,752,626 - 2,772,538 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,802,639 - 2,821,413 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,742,331 - 2,761,414 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,742,654 - 2,761,412NCBI
Celera163,001,895 - 3,020,980 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,769,571 - 2,788,653 (+)NCBIHuRef
CHM1_1162,802,386 - 2,821,457 (+)NCBICHM1_1
T2T-CHM13v2.0162,772,853 - 2,791,630 (+)NCBIT2T-CHM13v2.0
Srrm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,009,501 - 24,043,715 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,009,506 - 24,043,715 (+)EnsemblGRCm39 Ensembl
GRCm381723,790,527 - 23,824,741 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,790,532 - 23,824,741 (+)EnsemblGRCm38mm10GRCm38
MGSCv371723,940,154 - 23,961,708 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,530,848 - 23,552,358 (+)NCBIMGSCv36mm8
Celera1724,297,071 - 24,319,127 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.07NCBI
Srrm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,320,059 - 13,353,337 (+)NCBIGRCr8
mRatBN7.21012,815,471 - 12,848,750 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,815,471 - 12,848,751 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,560,149 - 17,593,313 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,048,938 - 17,082,103 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,548,336 - 12,581,526 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,128,820 - 13,162,956 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,145,099 - 13,162,343 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,948,282 - 12,982,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,066,871 - 13,081,983 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,051,311 - 13,084,720 (+)NCBI
Celera1012,510,616 - 12,543,690 (+)NCBICelera
Cytogenetic Map10q12NCBI
Srrm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,482,154 - 14,497,639 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,478,350 - 14,498,152 (+)NCBIChiLan1.0ChiLan1.0
SRRM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2183,257,612 - 3,276,327 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1167,038,665 - 7,057,379 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,612,386 - 1,631,177 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,865,810 - 2,884,902 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,865,810 - 2,884,902 (+)Ensemblpanpan1.1panPan2
SRRM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,291,847 - 38,310,624 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,291,842 - 38,393,924 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,532,055 - 39,550,491 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,602,410 - 38,620,868 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl638,602,405 - 38,620,865 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,288,079 - 38,306,513 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,260,566 - 38,278,981 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,736,665 - 38,755,113 (+)NCBIUU_Cfam_GSD_1.0
Srrm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,413,162 - 105,429,336 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,280,155 - 1,295,779 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,280,104 - 1,296,301 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRRM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,275,288 - 39,293,747 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,275,274 - 39,293,741 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,613,487 - 40,631,943 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRRM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,570,566 - 2,589,355 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,571,109 - 2,585,640 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,322,637 - 28,342,292 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019143   ⟹   ENSHGLP00000018954
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624824594,790 - 609,750 (-)Ensembl
RefSeq Acc Id: XM_021244302   ⟹   XP_021099961
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,203 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244303   ⟹   XP_021099962
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,203 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244304   ⟹   XP_021099963
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,203 - 613,222 (-)NCBI
RefSeq Acc Id: XM_021244305   ⟹   XP_021099964
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,883 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244306   ⟹   XP_021099965
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,883 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244307   ⟹   XP_021099966
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,883 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244308   ⟹   XP_021099967
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,203 - 613,222 (-)NCBI
RefSeq Acc Id: XM_021244309   ⟹   XP_021099968
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824596,580 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244310   ⟹   XP_021099969
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824596,378 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244311   ⟹   XP_021099970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824594,203 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244312   ⟹   XP_021099971
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824596,580 - 613,223 (-)NCBI
RefSeq Acc Id: XM_021244313   ⟹   XP_021099972
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624824605,937 - 613,225 (-)NCBI
RefSeq Acc Id: XP_021099962   ⟸   XM_021244303
- Peptide Label: isoform X2
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099970   ⟸   XM_021244311
- Peptide Label: isoform X9
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099961   ⟸   XM_021244302
- Peptide Label: isoform X1
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099967   ⟸   XM_021244308
- Peptide Label: isoform X7
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099963   ⟸   XM_021244304
- Peptide Label: isoform X3
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099966   ⟸   XM_021244307
- Peptide Label: isoform X6
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099965   ⟸   XM_021244306
- Peptide Label: isoform X5
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099964   ⟸   XM_021244305
- Peptide Label: isoform X4
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099969   ⟸   XM_021244310
- Peptide Label: isoform X8
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099971   ⟸   XM_021244312
- Peptide Label: isoform X10
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099968   ⟸   XM_021244309
- Peptide Label: isoform X8
- UniProtKB: G5B1K2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099972   ⟸   XM_021244313
- Peptide Label: isoform X11
Ensembl Acc Id: ENSHGLP00000018954   ⟸   ENSHGLT00000019143


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013586 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019143 ENTREZGENE
InterPro mRNA_splic_Cwf21_dom UniProtKB/TrEMBL
  Spt5_C_dom UniProtKB/TrEMBL
  SRRM2_cwf21 UniProtKB/TrEMBL
  SRRM_Domain-Containing UniProtKB/TrEMBL
NCBI Gene Srrm2 ENTREZGENE
PANTHER SERINE/ARGININE REPETITIVE MATRIX PROTEIN 2 UniProtKB/TrEMBL
  SERINE/ARGININE REPETITIVE MATRIX PROTEIN 3-RELATED UniProtKB/TrEMBL
Pfam cwf21 UniProtKB/TrEMBL
SMART CTD UniProtKB/TrEMBL
UniProt A0AAX6RQ83_HETGA UniProtKB/TrEMBL
  A0AAX6RRQ6_HETGA UniProtKB/TrEMBL
  A0AAX6RT65_HETGA UniProtKB/TrEMBL
  A0AAX6RT99_HETGA UniProtKB/TrEMBL
  A0AAX6RTI5_HETGA UniProtKB/TrEMBL
  A0AAX6RTP4_HETGA UniProtKB/TrEMBL
  A0AAX6RTX5_HETGA UniProtKB/TrEMBL
  A0AAX6RUI8_HETGA UniProtKB/TrEMBL
  A0AAX6RV25_HETGA UniProtKB/TrEMBL
  A0AAX6RW37_HETGA UniProtKB/TrEMBL
  A0AAX6RXA0_HETGA UniProtKB/TrEMBL
  G5B1K2 ENTREZGENE, UniProtKB/TrEMBL