Dynlrb2 (dynein light chain roadblock-type 2) - Rat Genome Database

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Gene: Dynlrb2 (dynein light chain roadblock-type 2) Heterocephalus glaber
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Symbol: Dynlrb2
Name: dynein light chain roadblock-type 2
RGD ID: 18923846
Description: ENCODES a protein that exhibits dynein intermediate chain binding (inferred); INVOLVED IN microtubule-based movement (inferred); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH cataract 21 multiple types (ortholog); developmental and epileptic encephalopathy 1 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic dynein complex (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,804,890 - 6,814,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,805,245 - 6,814,227 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dynlrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,804,890 - 6,814,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,805,245 - 6,814,227 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DYNLRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381680,540,734 - 80,550,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1680,540,734 - 80,550,811 (+)EnsemblGRCh38hg38GRCh38
GRCh371680,574,631 - 80,584,708 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361679,132,355 - 79,142,042 (+)NCBINCBI36Build 36hg18NCBI36
Build 341679,132,354 - 79,142,040NCBI
Celera1664,873,265 - 64,882,963 (+)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1666,331,392 - 66,341,090 (+)NCBIHuRef
CHM1_11681,986,336 - 81,996,023 (+)NCBICHM1_1
T2T-CHM13v2.01686,602,399 - 86,612,488 (+)NCBIT2T-CHM13v2.0
Dynlrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398117,231,754 - 117,242,654 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8117,231,713 - 117,242,654 (+)EnsemblGRCm39 Ensembl
GRCm388116,505,015 - 116,515,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8116,504,974 - 116,515,915 (+)EnsemblGRCm38mm10GRCm38
MGSCv378119,028,915 - 119,039,815 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368119,390,992 - 119,401,892 (+)NCBIMGSCv36mm8
Celera8120,722,918 - 120,733,815 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map863.07NCBI
Dynlrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81961,428,782 - 61,440,331 (+)NCBIGRCr8
mRatBN7.21944,520,134 - 44,531,384 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1944,520,134 - 44,531,387 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1951,343,658 - 51,354,906 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01951,997,103 - 52,008,357 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,238,114 - 54,249,368 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,016,919 - 49,028,400 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,016,891 - 49,028,404 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01959,812,610 - 59,823,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41946,546,841 - 46,559,015 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11946,551,724 - 46,563,916 (-)NCBI
Celera1943,808,532 - 43,820,118 (+)NCBICelera
Cytogenetic Map19q12NCBI
Dynlrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555223,353,087 - 3,365,045 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555223,353,087 - 3,364,276 (+)NCBIChiLan1.0ChiLan1.0
DYNLRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21890,280,732 - 90,293,480 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,200,015 - 96,212,775 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,138,632 - 61,148,817 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11680,567,709 - 80,577,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1680,566,963 - 80,577,609 (+)Ensemblpanpan1.1panPan2
DYNLRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1571,169,469 - 71,179,067 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl571,169,469 - 71,179,010 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha571,119,283 - 71,128,891 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0571,474,310 - 71,483,923 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl571,474,305 - 71,484,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1571,417,257 - 71,426,870 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0571,253,676 - 71,263,066 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,730,501 - 71,740,115 (-)NCBIUU_Cfam_GSD_1.0
Dynlrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934931,293,761 - 31,302,742 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647528,286,390 - 28,296,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647528,286,434 - 28,295,345 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl67,649,699 - 7,661,308 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.167,650,444 - 7,661,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.267,608,540 - 7,613,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1565,994,915 - 66,009,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl565,995,228 - 66,004,804 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660479,828,495 - 9,837,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000013693   ⟹   ENSHGLP00000013552
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247466,804,890 - 6,814,724 (-)Ensembl
RefSeq Acc Id: XM_004842810   ⟹   XP_004842867
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247466,805,245 - 6,814,227 (-)NCBI
RefSeq Acc Id: XM_021256678   ⟹   XP_021112337
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247466,805,245 - 6,813,727 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842867 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112337 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013552
GenBank Protein JAO02635 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004842867   ⟸   XM_004842810
- Peptide Label: isoform X2
- UniProtKB: A0A0P6K7U6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112337   ⟸   XM_021256678
- Peptide Label: isoform X1
Ensembl Acc Id: ENSHGLP00000013552   ⟸   ENSHGLT00000013693


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009690 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013693 ENTREZGENE
Gene3D-CATH Dynein light chain 2a, cytoplasmic UniProtKB/TrEMBL
InterPro DYNLRB1/2 UniProtKB/TrEMBL
  Roadblock/LAMTOR2_dom UniProtKB/TrEMBL
KEGG Report hgl:101697213 UniProtKB/TrEMBL
NCBI Gene Dynlrb2 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN ROADBLOCK UniProtKB/TrEMBL
  DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 UniProtKB/TrEMBL
Pfam Robl_LC7 UniProtKB/TrEMBL
PIRSF DLC7 UniProtKB/TrEMBL
SMART Robl_LC7 UniProtKB/TrEMBL
Superfamily-SCOP Roadblock/LC7 domain UniProtKB/TrEMBL
UniProt A0A0P6K7U6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6STD4_HETGA UniProtKB/TrEMBL