DYNLRB2 (dynein light chain roadblock-type 2) - Rat Genome Database

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Gene: DYNLRB2 (dynein light chain roadblock-type 2) Canis lupus familiaris
Analyze
Symbol: DYNLRB2
Name: dynein light chain roadblock-type 2
RGD ID: 12336576
Description: ENCODES a protein that exhibits dynein intermediate chain binding (inferred); INVOLVED IN microtubule-based movement (inferred); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH cataract 21 multiple types (ortholog); developmental and epileptic encephalopathy 1 (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic dynein complex (inferred); cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1571,169,469 - 71,179,067 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl571,169,469 - 71,179,010 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha571,119,283 - 71,128,891 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0571,474,310 - 71,483,923 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl571,474,305 - 71,484,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1571,417,257 - 71,426,870 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0571,253,676 - 71,263,066 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,730,501 - 71,740,115 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DYNLRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1571,169,469 - 71,179,067 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl571,169,469 - 71,179,010 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha571,119,283 - 71,128,891 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0571,474,310 - 71,483,923 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl571,474,305 - 71,484,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1571,417,257 - 71,426,870 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0571,253,676 - 71,263,066 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0571,730,501 - 71,740,115 (-)NCBIUU_Cfam_GSD_1.0
DYNLRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381680,540,734 - 80,550,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1680,540,734 - 80,550,811 (+)EnsemblGRCh38hg38GRCh38
GRCh371680,574,631 - 80,584,708 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361679,132,355 - 79,142,042 (+)NCBINCBI36Build 36hg18NCBI36
Build 341679,132,354 - 79,142,040NCBI
Celera1664,873,265 - 64,882,963 (+)NCBICelera
Cytogenetic Map16q23.2NCBI
HuRef1666,331,392 - 66,341,090 (+)NCBIHuRef
CHM1_11681,986,336 - 81,996,023 (+)NCBICHM1_1
T2T-CHM13v2.01686,602,399 - 86,612,488 (+)NCBIT2T-CHM13v2.0
Dynlrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398117,231,754 - 117,242,654 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8117,231,713 - 117,242,654 (+)EnsemblGRCm39 Ensembl
GRCm388116,505,015 - 116,515,915 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8116,504,974 - 116,515,915 (+)EnsemblGRCm38mm10GRCm38
MGSCv378119,028,915 - 119,039,815 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368119,390,992 - 119,401,892 (+)NCBIMGSCv36mm8
Celera8120,722,918 - 120,733,815 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map863.07NCBI
Dynlrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81961,428,782 - 61,440,331 (+)NCBIGRCr8
mRatBN7.21944,520,134 - 44,531,384 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1944,520,134 - 44,531,387 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1951,343,658 - 51,354,906 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01951,997,103 - 52,008,357 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01954,238,114 - 54,249,368 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01949,016,919 - 49,028,400 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,016,891 - 49,028,404 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01959,812,610 - 59,823,939 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41946,546,841 - 46,559,015 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11946,551,724 - 46,563,916 (-)NCBI
Celera1943,808,532 - 43,820,118 (+)NCBICelera
Cytogenetic Map19q12NCBI
Dynlrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555223,353,087 - 3,365,045 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555223,353,087 - 3,364,276 (+)NCBIChiLan1.0ChiLan1.0
DYNLRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21890,280,732 - 90,293,480 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11696,200,015 - 96,212,775 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01661,138,632 - 61,148,817 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11680,567,709 - 80,577,616 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1680,566,963 - 80,577,609 (+)Ensemblpanpan1.1panPan2
Dynlrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934931,293,761 - 31,302,742 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647528,286,390 - 28,296,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647528,286,434 - 28,295,345 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl67,649,699 - 7,661,308 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.167,650,444 - 7,661,380 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.267,608,540 - 7,613,434 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1565,994,915 - 66,009,154 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl565,995,228 - 66,004,804 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660479,828,495 - 9,837,976 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247466,804,890 - 6,814,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247466,805,245 - 6,814,227 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DYNLRB2
118 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000031865   ⟹   ENSCAFP00000029670
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl571,169,469 - 71,179,008 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000082152   ⟹   ENSCAFP00000046009
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl571,169,667 - 71,179,010 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845037147   ⟹   ENSCAFP00845029090
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl571,474,305 - 71,484,080 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845037191   ⟹   ENSCAFP00845029125
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl571,474,310 - 71,483,852 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845037235   ⟹   ENSCAFP00845029160
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl571,474,508 - 71,483,854 (-)Ensembl
RefSeq Acc Id: XM_038477060   ⟹   XP_038332988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1571,417,257 - 71,426,870 (-)NCBI
RefSeq Acc Id: XM_038538246   ⟹   XP_038394174
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0571,730,501 - 71,740,115 (-)NCBI
RefSeq Acc Id: XM_038602372   ⟹   XP_038458300
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0571,253,676 - 71,263,066 (-)NCBI
RefSeq Acc Id: XM_038666979   ⟹   XP_038522907
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0571,474,310 - 71,483,923 (-)NCBI
RefSeq Acc Id: XM_536771   ⟹   XP_536771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1571,169,469 - 71,179,067 (-)NCBI
Dog10K_Boxer_Tasha571,119,283 - 71,128,891 (-)NCBI
Sequence:
RefSeq Acc Id: XP_536771   ⟸   XM_536771
- UniProtKB: A0A8C0LVS6 (UniProtKB/TrEMBL),   A0A8C0JPP4 (UniProtKB/TrEMBL),   A0A8I3PEX5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000046009   ⟸   ENSCAFT00000082152
Ensembl Acc Id: ENSCAFP00000029670   ⟸   ENSCAFT00000031865
RefSeq Acc Id: XP_038332988   ⟸   XM_038477060
RefSeq Acc Id: XP_038458300   ⟸   XM_038602372
RefSeq Acc Id: XP_038522907   ⟸   XM_038666979
- UniProtKB: A0A8C0LVS6 (UniProtKB/TrEMBL),   A0A8C0JPP4 (UniProtKB/TrEMBL),   A0A8I3PEX5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038394174   ⟸   XM_038538246
- UniProtKB: A0A8C0JPP4 (UniProtKB/TrEMBL),   A0A8C0LVS6 (UniProtKB/TrEMBL),   A0A8I3PEX5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845029125   ⟸   ENSCAFT00845037191
Ensembl Acc Id: ENSCAFP00845029160   ⟸   ENSCAFT00845037235
Ensembl Acc Id: ENSCAFP00845029090   ⟸   ENSCAFT00845037147
Protein Domains
Roadblock/LAMTOR2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020024 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001548 UniProtKB/TrEMBL
  ENSCAFG00040009065 UniProtKB/TrEMBL
  ENSCAFG00845021057 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031865.5 UniProtKB/TrEMBL
  ENSCAFT00000082152.2 UniProtKB/TrEMBL
  ENSCAFT00030002757.1 UniProtKB/TrEMBL
  ENSCAFT00030002775.1 UniProtKB/TrEMBL
  ENSCAFT00040016823.1 UniProtKB/TrEMBL
  ENSCAFT00040016844.1 UniProtKB/TrEMBL
  ENSCAFT00845037147.1 UniProtKB/TrEMBL
  ENSCAFT00845037191 ENTREZGENE
  ENSCAFT00845037191.1 UniProtKB/TrEMBL
  ENSCAFT00845037235.1 UniProtKB/TrEMBL
Gene3D-CATH Dynein light chain 2a, cytoplasmic UniProtKB/TrEMBL
InterPro DYNLRB1/2 UniProtKB/TrEMBL
  Roadblock/LAMTOR2_dom UniProtKB/TrEMBL
KEGG Report cfa:479636 UniProtKB/TrEMBL
NCBI Gene DYNLRB2 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN ROADBLOCK UniProtKB/TrEMBL
  DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 UniProtKB/TrEMBL
Pfam Robl_LC7 UniProtKB/TrEMBL
PIRSF DLC7 UniProtKB/TrEMBL
SMART Robl_LC7 UniProtKB/TrEMBL
Superfamily-SCOP Roadblock/LC7 domain UniProtKB/TrEMBL
UniProt A0A8C0JPP4 ENTREZGENE
  A0A8C0LVS6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RAB0_CANLF UniProtKB/TrEMBL
  A0A8I3P6M3_CANLF UniProtKB/TrEMBL
  A0A8I3PA48_CANLF UniProtKB/TrEMBL
  A0A8I3PEX5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40153 ENTREZGENE