Arhgap25 (Rho GTPase activating protein 25) - Rat Genome Database

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Gene: Arhgap25 (Rho GTPase activating protein 25) Heterocephalus glaber
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Symbol: Arhgap25
Name: Rho GTPase activating protein 25
RGD ID: 18923282
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN actin filament organization (inferred); negative regulation of small GTPase mediated signal transduction (inferred); phagocytosis, engulfment (inferred); FOUND IN phagocytic cup (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 25
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247624,523,920 - 4,596,253 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247624,520,420 - 4,596,276 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Arhgap25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247624,523,920 - 4,596,253 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247624,520,420 - 4,596,276 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ARHGAP25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38268,710,544 - 68,826,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl268,679,601 - 68,826,833 (+)EnsemblGRCh38hg38GRCh38
GRCh37268,961,943 - 69,053,965 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36268,815,472 - 68,907,469 (+)NCBINCBI36Build 36hg18NCBI36
Build 34268,913,583 - 68,965,606NCBI
Celera268,812,361 - 68,904,457 (+)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef268,698,170 - 68,790,208 (+)NCBIHuRef
CHM1_1268,891,239 - 68,983,315 (+)NCBICHM1_1
T2T-CHM13v2.0268,722,999 - 68,839,279 (+)NCBIT2T-CHM13v2.0
Arhgap25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39687,435,526 - 87,510,241 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl687,435,527 - 87,510,241 (-)EnsemblGRCm39 Ensembl
GRCm38687,458,544 - 87,533,261 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,458,545 - 87,533,259 (-)EnsemblGRCm38mm10GRCm38
MGSCv37687,409,379 - 87,483,229 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36687,425,026 - 87,498,876 (-)NCBIMGSCv36mm8
Celera689,392,340 - 89,468,487 (-)NCBICelera
Cytogenetic Map6D1NCBI
cM Map638.01NCBI
Arhgap25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,454,151 - 121,532,293 (-)NCBIGRCr8
mRatBN7.24119,896,844 - 119,974,982 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,896,844 - 119,974,982 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4125,368,652 - 125,448,563 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04121,143,426 - 121,223,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04119,767,660 - 119,847,573 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04119,249,682 - 119,327,822 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4119,249,682 - 119,327,822 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,812,925 - 183,891,522 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,620,926 - 121,700,835 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4108,865,660 - 108,943,601 (-)NCBICelera
Cytogenetic Map4q34NCBI
Arhgap25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542416,164,324 - 16,241,481 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542416,166,285 - 16,241,481 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21257,588,822 - 57,681,052 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A57,592,770 - 57,685,000 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A68,775,637 - 68,867,870 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A69,897,974 - 69,989,955 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A69,897,974 - 69,989,955 (+)Ensemblpanpan1.1panPan2
ARHGAP25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11067,597,527 - 67,687,721 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1067,487,709 - 67,576,482 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01068,619,760 - 68,709,809 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1068,619,811 - 68,709,807 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11068,302,032 - 68,391,920 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01068,601,892 - 68,692,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01068,895,976 - 68,988,211 (+)NCBIUU_Cfam_GSD_1.0
Arhgap25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629215,433,090 - 15,515,494 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649113,055,790 - 13,138,227 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649113,055,790 - 13,138,370 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl373,556,565 - 73,649,849 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1373,556,561 - 73,649,997 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2377,002,872 - 77,096,317 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11438,297,738 - 38,389,692 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1438,297,213 - 38,389,777 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604573,601,639 - 73,692,238 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025583   ⟹   ENSHGLP00000025360
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247624,523,920 - 4,596,253 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000025584   ⟹   ENSHGLP00000025361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247624,523,920 - 4,564,317 (-)Ensembl
RefSeq Acc Id: XM_004849936   ⟹   XP_004849993
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247624,520,420 - 4,596,276 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004849993 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025360
  ENSHGLP00100003537
GenBank Protein JAN96998 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004849993   ⟸   XM_004849936
- UniProtKB: A0A0P6IY48 (UniProtKB/TrEMBL),   G5BNY5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025361   ⟸   ENSHGLT00000025584
Ensembl Acc Id: ENSHGLP00000025360   ⟸   ENSHGLT00000025583


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018071 Ensembl, ENTREZGENE
  ENSHGLG00100002693 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000025583 ENTREZGENE
  ENSHGLT00100003597 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
KEGG Report hgl:101703252 UniProtKB/TrEMBL
NCBI Gene Arhgap25 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 25 UniProtKB/TrEMBL
  SPERMATHECAL PHYSIOLOGY VARIANT UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
UniProt A0A0P6IY48 ENTREZGENE, UniProtKB/TrEMBL
  G5BNY5 ENTREZGENE, UniProtKB/TrEMBL