Lrrc18 (leucine rich repeat containing 18) - Rat Genome Database

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Gene: Lrrc18 (leucine rich repeat containing 18) Heterocephalus glaber
Analyze
Symbol: Lrrc18
Name: leucine rich repeat containing 18
RGD ID: 18922614
Description: ASSOCIATED WITH Cockayne syndrome B (ortholog); megacolon (ortholog); schizophrenia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat-containing protein 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624928980,389 - 1,004,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624928980,324 - 1,004,150 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Lrrc18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624928980,389 - 1,004,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624928980,324 - 1,004,150 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LRRC18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381048,909,480 - 48,939,840 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1048,909,480 - 48,939,840 (-)EnsemblGRCh38hg38GRCh38
GRCh371050,117,525 - 50,147,885 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361049,787,534 - 49,792,286 (-)NCBINCBI36Build 36hg18NCBI36
Build 341049,787,536 - 49,792,288NCBI
Celera1043,703,127 - 43,707,879 (-)NCBICelera
Cytogenetic Map10q11.23NCBI
HuRef1044,382,681 - 44,387,433 (-)NCBIHuRef
CHM1_11050,399,155 - 50,403,907 (-)NCBICHM1_1
T2T-CHM13v2.01049,758,686 - 49,789,019 (-)NCBIT2T-CHM13v2.0
Lrrc18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,713,339 - 32,737,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1432,713,339 - 32,737,248 (+)EnsemblGRCm39 Ensembl
GRCm381432,991,382 - 33,015,300 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,991,382 - 33,015,291 (+)EnsemblGRCm38mm10GRCm38
MGSCv371433,804,568 - 33,828,478 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361431,820,492 - 31,844,384 (+)NCBIMGSCv36mm8
Celera1429,251,093 - 29,275,024 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.61NCBI
Lrrc18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8168,259,083 - 8,283,722 (+)NCBIGRCr8
mRatBN7.2168,253,524 - 8,277,141 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl168,254,352 - 8,277,437 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx168,273,142 - 8,291,825 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0169,418,043 - 9,436,726 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0168,266,491 - 8,284,806 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0169,234,341 - 9,258,849 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,235,888 - 9,258,538 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01611,196,474 - 11,218,933 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4168,529,683 - 8,554,281 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1168,529,680 - 8,554,277 (+)NCBI
Celera166,928,507 - 6,951,792 (-)NCBICelera
Cytogenetic Map16p16NCBI
Lrrc18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555561,213,517 - 1,237,275 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555561,213,871 - 1,237,281 (+)NCBIChiLan1.0ChiLan1.0
LRRC18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2861,174,202 - 61,205,658 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11061,179,521 - 61,210,977 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01045,309,911 - 45,331,912 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LRRC18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128822,579 - 856,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl28830,105 - 834,201 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,051,350 - 1,084,412 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.028998,365 - 1,031,443 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.128808,202 - 830,558 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028840,839 - 873,922 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028963,920 - 996,994 (-)NCBIUU_Cfam_GSD_1.0
Lrrc18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721380,100,224 - 80,128,753 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367281,326,723 - 1,327,490 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367281,306,756 - 1,327,490 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1489,571,919 - 89,577,303 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11489,571,911 - 89,589,479 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21497,366,156 - 97,387,555 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1942,861,868 - 42,887,733 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl942,861,657 - 42,889,270 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660482,629,901 - 2,649,307 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000001956   ⟹   ENSHGLP00000001910
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624928980,389 - 999,876 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000001957   ⟹   ENSHGLP00000001911
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624928983,765 - 1,004,137 (+)Ensembl
RefSeq Acc Id: XM_004874533   ⟹   XP_004874590
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624928980,324 - 1,004,148 (+)NCBI
RefSeq Acc Id: XM_021251945   ⟹   XP_021107604
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624928980,474 - 1,004,148 (+)NCBI
RefSeq Acc Id: XM_021251946   ⟹   XP_021107605
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624928980,326 - 1,004,148 (+)NCBI
RefSeq Acc Id: XM_021251947   ⟹   XP_021107606
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624928980,324 - 1,004,150 (+)NCBI
RefSeq Acc Id: XM_021251948   ⟹   XP_021107607
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624928980,325 - 1,004,150 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021107606   ⟸   XM_021251947
- UniProtKB: A0A0P6JDX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004874590   ⟸   XM_004874533
- UniProtKB: A0A0P6JDX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021107607   ⟸   XM_021251948
- UniProtKB: A0A0P6JDX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021107605   ⟸   XM_021251946
- UniProtKB: A0A0P6JDX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021107604   ⟸   XM_021251945
- UniProtKB: A0A0P6JDX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000001910   ⟸   ENSHGLT00000001956
RefSeq Acc Id: ENSHGLP00000001911   ⟸   ENSHGLT00000001957


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000001458 Ensembl, ENTREZGENE
  ENSHGLG00100012920 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000001957 ENTREZGENE
  ENSHGLT00100017701 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Lrrc18 ENTREZGENE
PANTHER NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE-RELATED UniProtKB/TrEMBL
  PTHR48051 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A0P6JDX1 ENTREZGENE, UniProtKB/TrEMBL