Ddx50 (DExD-box helicase 50) - Rat Genome Database

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Gene: Ddx50 (DExD-box helicase 50) Heterocephalus glaber
Analyze
Symbol: Ddx50
Name: DExD-box helicase 50
RGD ID: 18922414
Description: ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DDX50; DEAD-box helicase 50
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,125,155 - 3,171,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,125,357 - 3,171,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nucleolus  (IEA)
plasma membrane  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Ddx50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,125,155 - 3,171,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,125,357 - 3,171,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DDX50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,901,315 - 68,946,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,901,286 - 68,946,847 (+)EnsemblGRCh38hg38GRCh38
GRCh371070,661,071 - 70,706,603 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361070,331,040 - 70,376,609 (+)NCBINCBI36Build 36hg18NCBI36
Build 341070,331,039 - 70,376,608NCBI
Celera1063,936,917 - 63,982,475 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1064,662,530 - 64,708,505 (+)NCBIHuRef
CHM1_11070,942,658 - 70,988,331 (+)NCBICHM1_1
T2T-CHM13v2.01069,770,124 - 69,825,744 (+)NCBIT2T-CHM13v2.0
Ddx50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,451,571 - 62,487,260 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,451,674 - 62,486,997 (-)EnsemblGRCm39 Ensembl
GRCm381062,615,792 - 62,658,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,615,895 - 62,651,218 (-)EnsemblGRCm38mm10GRCm38
MGSCv371062,078,771 - 62,113,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361062,011,380 - 62,046,555 (-)NCBIMGSCv36mm8
Celera1063,719,405 - 63,752,831 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.44NCBI
Ddx50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,104,354 - 31,133,652 (-)NCBIGRCr8
mRatBN7.22030,561,623 - 30,591,324 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,560,544 - 30,591,152 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,572,595 - 31,601,894 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,963,508 - 30,992,808 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,700,270 - 31,729,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,239,736 - 32,269,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,239,748 - 32,269,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02034,024,302 - 34,054,135 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,867,955 - 29,897,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12029,881,754 - 29,900,262 (-)NCBI
Celera2031,980,681 - 32,009,951 (-)NCBICelera
Cytogenetic Map20q11NCBI
Ddx50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543722,086,704 - 22,118,177 (-)NCBIChiLan1.0ChiLan1.0
DDX50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,042,949 - 81,102,571 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,048,577 - 81,098,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01065,367,689 - 65,414,023 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11067,902,219 - 67,948,207 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1067,902,219 - 67,948,207 (+)Ensemblpanpan1.1panPan2
DDX50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,073,013 - 20,102,622 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl420,073,094 - 20,102,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,203,664 - 20,233,018 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0420,345,617 - 20,374,931 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,345,637 - 20,374,939 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,246,345 - 20,275,650 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0420,449,176 - 20,478,530 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,792,305 - 20,821,657 (+)NCBIUU_Cfam_GSD_1.0
Ddx50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,965,596 - 61,000,626 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,458,329 - 9,493,319 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,463,049 - 9,493,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1471,989,584 - 72,030,980 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11471,989,137 - 72,030,996 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,004,480 - 78,045,914 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX50
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,378,977 - 62,424,108 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl962,377,491 - 62,424,006 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604823,121,101 - 23,168,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000018985   ⟹   ENSHGLP00000018797
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247543,125,155 - 3,171,584 (+)Ensembl
RefSeq Acc Id: XM_004846173   ⟹   XP_004846230
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247543,125,358 - 3,171,584 (+)NCBI
RefSeq Acc Id: XM_004846174   ⟹   XP_004846231
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247543,125,357 - 3,171,584 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004846230 (Get FASTA)   NCBI Sequence Viewer  
  XP_004846231 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB05413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018797
  ENSHGLP00100029533
GenBank Protein JAN98393 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004846231   ⟸   XM_004846174
- Peptide Label: isoform X2
- UniProtKB: A0AAX6P8F4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004846230   ⟸   XM_004846173
- Peptide Label: isoform X1
- UniProtKB: G5B802 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000018797   ⟸   ENSHGLT00000018985


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013466 Ensembl, ENTREZGENE
  ENSHGLG00100017191 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018985 ENTREZGENE
  ENSHGLT00100053652 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.2280 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DEAD_box_RNA_helicase UniProtKB/TrEMBL
  GUCT UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
KEGG Report hgl:101704536 UniProtKB/TrEMBL
NCBI Gene Ddx50 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE RHLE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE RHLE-RELATED UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  GUCT UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0AAX6P8F4 ENTREZGENE, UniProtKB/TrEMBL
  G5B802 ENTREZGENE, UniProtKB/TrEMBL