Ddx50 (DExD-box helicase 50) - Rat Genome Database

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Gene: Ddx50 (DExD-box helicase 50) Chinchilla lanigera
Analyze
Symbol: Ddx50
Name: DExD-box helicase 50
RGD ID: 8807082
Description: ASSOCIATED WITH genetic disease (ortholog); prostate cancer (ortholog); FOUND IN nucleolus (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DDX50; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; DEAD-box helicase 50
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543722,086,704 - 22,118,177 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ddx50
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543722,086,704 - 22,118,177 (-)NCBIChiLan1.0ChiLan1.0
DDX50
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,901,315 - 68,946,847 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,901,286 - 68,946,847 (+)EnsemblGRCh38hg38GRCh38
GRCh371070,661,071 - 70,706,603 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361070,331,040 - 70,376,609 (+)NCBINCBI36Build 36hg18NCBI36
Build 341070,331,039 - 70,376,608NCBI
Celera1063,936,917 - 63,982,475 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1064,662,530 - 64,708,505 (+)NCBIHuRef
CHM1_11070,942,658 - 70,988,331 (+)NCBICHM1_1
T2T-CHM13v2.01069,770,124 - 69,825,744 (+)NCBIT2T-CHM13v2.0
Ddx50
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,451,571 - 62,487,260 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,451,674 - 62,486,997 (-)EnsemblGRCm39 Ensembl
GRCm381062,615,792 - 62,658,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,615,895 - 62,651,218 (-)EnsemblGRCm38mm10GRCm38
MGSCv371062,078,771 - 62,113,946 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361062,011,380 - 62,046,555 (-)NCBIMGSCv36mm8
Celera1063,719,405 - 63,752,831 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.44NCBI
Ddx50
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82031,104,354 - 31,133,652 (-)NCBIGRCr8
mRatBN7.22030,561,623 - 30,591,324 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2030,560,544 - 30,591,152 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2031,572,595 - 31,601,894 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02030,963,508 - 30,992,808 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02031,700,270 - 31,729,596 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02032,239,736 - 32,269,522 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2032,239,748 - 32,269,145 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02034,024,302 - 34,054,135 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42029,867,955 - 29,897,253 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12029,881,754 - 29,900,262 (-)NCBI
Celera2031,980,681 - 32,009,951 (-)NCBICelera
Cytogenetic Map20q11NCBI
DDX50
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2881,042,949 - 81,102,571 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11081,048,577 - 81,098,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01065,367,689 - 65,414,023 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11067,902,219 - 67,948,207 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1067,902,219 - 67,948,207 (+)Ensemblpanpan1.1panPan2
DDX50
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1420,073,013 - 20,102,622 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl420,073,094 - 20,102,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha420,203,664 - 20,233,018 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0420,345,617 - 20,374,931 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl420,345,637 - 20,374,939 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1420,246,345 - 20,275,650 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0420,449,176 - 20,478,530 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,792,305 - 20,821,657 (+)NCBIUU_Cfam_GSD_1.0
Ddx50
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721360,965,596 - 61,000,626 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,458,329 - 9,493,319 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,463,049 - 9,493,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDX50
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1471,989,584 - 72,030,980 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11471,989,137 - 72,030,996 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21478,004,480 - 78,045,914 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DDX50
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,378,977 - 62,424,108 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl962,377,491 - 62,424,006 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604823,121,101 - 23,168,135 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddx50
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247543,125,155 - 3,171,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247543,125,357 - 3,171,584 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005390102   ⟹   XP_005390159
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543722,086,704 - 22,118,177 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005390159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000018920
  ENSCLAP00000018920.1
Reference Protein Sequences
RefSeq Acc Id: XP_005390159   ⟸   XM_005390102
- UniProtKB: A0A8C2VXF2 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Helicase ATP-binding   Helicase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012957 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019105 ENTREZGENE
  ENSCLAT00000019105.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.2280 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  GUCT UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
NCBI Gene Ddx50 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE RHLE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE RHLE-RELATED UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  GUCT UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
UniProt A0A8C2VXF2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-04 Ddx50  DExD-box helicase 50    DEAD-box helicase 50  Symbol and/or name change 5135510 APPROVED
2016-08-03 Ddx50  DEAD-box helicase 50    DEAD (Asp-Glu-Ala-Asp) box polypeptide 50  Symbol and/or name change 5135510 APPROVED