Hpdl (4-hydroxyphenylpyruvate dioxygenase like) - Rat Genome Database

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Gene: Hpdl (4-hydroxyphenylpyruvate dioxygenase like) Heterocephalus glaber
Analyze
Symbol: Hpdl
Name: 4-hydroxyphenylpyruvate dioxygenase like
RGD ID: 18922049
Description: ENCODES a protein that exhibits 4-hydroxymandelate synthase activity (ortholog); INVOLVED IN aromatic amino acid metabolic process (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 4-hydroxyphenylpyruvate dioxygenase-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249061,236,450 - 1,237,565 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249061,235,307 - 1,238,381 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Hpdl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249061,236,450 - 1,237,565 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249061,235,307 - 1,238,381 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HPDL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38145,326,895 - 45,328,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl145,326,895 - 45,328,710 (+)EnsemblGRCh38hg38GRCh38
GRCh37145,792,567 - 45,794,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36145,565,132 - 45,566,934 (+)NCBINCBI36Build 36hg18NCBI36
Celera144,075,922 - 44,077,724 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef143,904,200 - 43,906,002 (+)NCBIHuRef
CHM1_1145,909,348 - 45,911,150 (+)NCBICHM1_1
T2T-CHM13v2.0145,198,451 - 45,200,266 (+)NCBIT2T-CHM13v2.0
Hpdl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,677,104 - 116,678,705 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,677,101 - 116,678,904 (-)EnsemblGRCm39 Ensembl
GRCm384116,819,907 - 116,821,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,819,904 - 116,821,707 (-)EnsemblGRCm38mm10GRCm38
MGSCv374116,492,512 - 116,494,113 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364116,317,839 - 116,319,440 (-)NCBIMGSCv36mm8
Celera4115,559,324 - 115,560,925 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.35NCBI
Hpdl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85135,523,258 - 135,524,864 (-)NCBIGRCr8
mRatBN7.25130,286,627 - 130,288,233 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5130,286,631 - 130,288,233 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,917,327 - 132,918,933 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,671,930 - 134,673,536 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,694,331 - 134,695,937 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,675,826 - 135,677,432 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,675,832 - 135,677,432 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05139,471,945 - 139,473,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45137,116,378 - 137,117,984 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15137,121,605 - 137,123,210 (-)NCBI
Celera5128,813,296 - 128,814,902 (-)NCBICelera
Cytogenetic Map5q35NCBI
Hpdl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546412,936,996 - 12,940,050 (-)NCBIChiLan1.0ChiLan1.0
HPDL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21181,480,018 - 181,481,687 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11180,621,287 - 180,623,136 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,629,560 - 44,631,394 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1145,988,044 - 45,989,883 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl145,988,494 - 45,989,609 (+)Ensemblpanpan1.1panPan2
HPDL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11515,019,273 - 15,028,932 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1515,027,472 - 15,028,671 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1515,140,618 - 15,150,283 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01515,174,596 - 15,184,265 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1515,182,797 - 15,183,996 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,971,693 - 14,981,350 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01515,039,578 - 15,049,242 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01515,111,689 - 15,121,352 (-)NCBIUU_Cfam_GSD_1.0
Hpdl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505860,657,068 - 60,658,485 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647426,481,883 - 26,482,998 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647426,481,300 - 26,483,143 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HPDL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6166,012,601 - 166,014,323 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16166,012,590 - 166,015,051 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26153,420,659 - 153,423,107 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HPDL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12087,463,202 - 87,465,467 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2087,463,636 - 87,464,748 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603329,496,866 - 29,498,911 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004872924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01102538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000028871   ⟹   ENSHGLP00000028404
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249061,236,450 - 1,237,565 (+)Ensembl
RefSeq Acc Id: XM_004872924   ⟹   XP_004872981
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249061,235,307 - 1,238,381 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004872981 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000028404
RefSeq Acc Id: XP_004872981   ⟸   XM_004872924
- UniProtKB: A0AAX6QH16 (UniProtKB/TrEMBL),   G5ARU2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000028404   ⟸   ENSHGLT00000028871


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020661 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000028871 ENTREZGENE
Gene3D-CATH 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 UniProtKB/TrEMBL
InterPro 4OHPhenylPyrv_dOase UniProtKB/TrEMBL
  4OHPhenylPyrv_dOase_C UniProtKB/TrEMBL
  4OHPhenylPyrv_dOase_N UniProtKB/TrEMBL
  Glyas_Bleomycin-R_OHBP_Dase UniProtKB/TrEMBL
  VOC UniProtKB/TrEMBL
NCBI Gene Hpdl ENTREZGENE
PANTHER 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE UniProtKB/TrEMBL
  4-HYDROXYPHENYLPYRUVATE DIOXYGENASE-LIKE PROTEIN UniProtKB/TrEMBL
PROSITE VOC UniProtKB/TrEMBL
Superfamily-SCOP Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UniProtKB/TrEMBL
UniProt A0AAX6QH16 ENTREZGENE, UniProtKB/TrEMBL
  G5ARU2 ENTREZGENE, UniProtKB/TrEMBL