Ubqln2 (ubiquilin 2) - Rat Genome Database

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Gene: Ubqln2 (ubiquilin 2) Heterocephalus glaber
Analyze
Symbol: Ubqln2
Name: ubiquilin 2
RGD ID: 18921042
Description: ENCODES a protein that exhibits identical protein binding (ortholog); molecular condensate scaffold activity (ortholog); INVOLVED IN negative regulation of clathrin-dependent endocytosis (ortholog); negative regulation of G protein-coupled receptor internalization (ortholog); positive regulation of ERAD pathway (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); amyotrophic lateral sclerosis type 15 (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ubiquilin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249101,548,249 - 1,550,126 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249101,547,942 - 1,551,323 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Ubqln2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249101,548,249 - 1,550,126 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249101,547,942 - 1,551,323 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UBQLN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X56,563,627 - 56,567,868 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX56,563,627 - 56,567,868 (+)EnsemblGRCh38hg38GRCh38
GRCh37X56,590,060 - 56,594,301 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X56,606,797 - 56,610,102 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X56,473,092 - 56,476,398NCBI
CeleraX60,422,310 - 60,425,727 (+)NCBICelera
Cytogenetic MapXp11.21NCBI
HuRefX53,642,196 - 53,645,647 (+)NCBIHuRef
CHM1_1X56,580,226 - 56,583,643 (+)NCBICHM1_1
T2T-CHM13v2.0X55,856,941 - 55,861,182 (+)NCBIT2T-CHM13v2.0
Ubqln2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X152,281,228 - 152,284,558 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX152,281,223 - 152,284,566 (+)EnsemblGRCm39 Ensembl
GRCm38X153,498,232 - 153,501,562 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX153,498,227 - 153,501,570 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X149,932,775 - 149,936,105 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X148,838,948 - 148,842,278 (+)NCBIMGSCv36mm8
CeleraX135,753,727 - 135,757,059 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Ubqln2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X21,228,809 - 21,232,228 (-)NCBIGRCr8
mRatBN7.2X17,853,086 - 17,856,505 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX17,853,114 - 17,856,505 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX15,251,663 - 15,255,083 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X24,869,844 - 24,873,264 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X18,312,169 - 18,315,589 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X18,723,313 - 18,726,732 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX18,723,341 - 18,726,732 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X19,487,954 - 19,491,373 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X37,992,907 - 37,996,327 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX18,131,544 - 18,134,964 (-)NCBICelera
Cytogenetic MapXq12NCBI
Ubqln2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554753,260,503 - 3,262,380 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554753,260,209 - 3,263,586 (+)NCBIChiLan1.0ChiLan1.0
UBQLN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X57,999,446 - 58,003,742 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X58,003,059 - 58,008,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X48,829,844 - 48,835,040 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X56,981,696 - 56,985,979 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX56,981,985 - 56,983,859 (+)Ensemblpanpan1.1panPan2
UBQLN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X47,860,923 - 47,864,282 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX39,057,141 - 39,060,488 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X48,117,445 - 48,120,792 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X47,357,992 - 47,361,339 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X48,101,497 - 48,104,844 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X48,016,846 - 48,020,193 (+)NCBIUU_Cfam_GSD_1.0
Ubqln2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X40,500,402 - 40,503,770 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936819532,037 - 533,920 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936819530,833 - 534,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBQLN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX48,948,389 - 48,950,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X48,948,062 - 48,951,392 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UBQLN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X52,486,154 - 52,489,531 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX52,486,454 - 52,488,328 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660866,589,262 - 6,593,708 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000028355   ⟹   ENSHGLP00000028014
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046249101,548,249 - 1,550,126 (+)Ensembl
RefSeq Acc Id: XM_004873568   ⟹   XP_004873625
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249101,547,942 - 1,551,323 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004873625 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15242 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000028014
RefSeq Acc Id: XP_004873625   ⟸   XM_004873568
- UniProtKB: G5C131 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000028014   ⟸   ENSHGLT00000028355


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000020145 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000028355 ENTREZGENE
Gene3D-CATH 1.10.260.100 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  STI1_HS-bd UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
  Ubiquilin UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Ubqln2 ENTREZGENE
PANTHER UBIQUILIN UniProtKB/TrEMBL
  UBIQUILIN-2 UniProtKB/TrEMBL
Pfam UBA UniProtKB/TrEMBL
  ubiquitin UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
  UBIQUITIN_2 UniProtKB/TrEMBL
SMART STI1 UniProtKB/TrEMBL
  UBA UniProtKB/TrEMBL
  UBQ UniProtKB/TrEMBL
Superfamily-SCOP ARM repeat UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  Ubiquitin-like UniProtKB/TrEMBL
UniProt G5C131 ENTREZGENE, UniProtKB/TrEMBL