Ctrc (chymotrypsin C) - Rat Genome Database

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Gene: Ctrc (chymotrypsin C) Heterocephalus glaber
Analyze
Symbol: Ctrc
Name: chymotrypsin C
RGD ID: 18918635
Description: ENCODES a protein that exhibits peptidase activity (inferred); serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN intracellular calcium ion homeostasis (ortholog); proteolysis (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); Chronic Pancreatitis (ortholog); Hereditary Pancreatitis (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Chymotrypsin-C; chymotrypsin-C preproprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247641,741,703 - 1,747,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247641,741,703 - 1,747,715 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ctrc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247641,741,703 - 1,747,712 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247641,741,703 - 1,747,715 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CTRC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38115,438,443 - 15,449,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl115,438,442 - 15,449,242 (+)EnsemblGRCh38hg38GRCh38
GRCh37115,764,939 - 15,775,737 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,637,525 - 15,645,740 (+)NCBINCBI36Build 36hg18NCBI36
Build 34115,510,266 - 15,518,459NCBI
Celera114,247,812 - 14,256,036 (+)NCBICelera
Cytogenetic Map1p36.21NCBI
HuRef114,284,975 - 14,292,965 (+)NCBIHuRef
CHM1_1115,563,607 - 15,571,831 (+)NCBICHM1_1
T2T-CHM13v2.0114,883,158 - 14,893,965 (+)NCBIT2T-CHM13v2.0
Ctrc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394141,565,550 - 141,573,598 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4141,565,550 - 141,573,670 (-)EnsemblGRCm39 Ensembl
GRCm384141,838,239 - 141,846,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4141,814,962 - 141,846,359 (-)EnsemblGRCm38mm10GRCm38
MGSCv374141,394,154 - 141,402,274 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364141,110,315 - 141,118,433 (-)NCBIMGSCv36mm8
Celera4143,663,843 - 143,672,528 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map474.75NCBI
Ctrc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85159,430,333 - 159,439,557 (-)NCBIGRCr8
mRatBN7.25154,147,314 - 154,156,540 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5154,147,316 - 154,156,528 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5156,832,248 - 156,841,319 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05158,605,546 - 158,614,617 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05158,594,698 - 158,603,769 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05160,394,677 - 160,403,373 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5160,394,580 - 160,405,050 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05164,106,200 - 164,115,282 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45160,742,491 - 160,755,332 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15160,748,258 - 160,765,508 (-)NCBI
Celera5152,500,014 - 152,508,395 (-)NCBICelera
Cytogenetic Map5q36NCBI
Ctrc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555272,714,210 - 2,719,598 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555272,714,001 - 2,719,598 (-)NCBIChiLan1.0ChiLan1.0
CTRC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21211,473,375 - 211,482,329 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,721,838 - 210,730,788 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0114,576,496 - 14,588,143 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1115,571,771 - 15,580,000 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl115,571,771 - 15,580,000 (+)Ensemblpanpan1.1panPan2
LOC478220
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1282,075,135 - 82,081,091 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,612,480 - 78,618,473 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0282,724,375 - 82,730,364 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1279,477,146 - 79,483,132 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0280,495,080 - 80,501,075 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,559,591 - 81,565,591 (-)NCBIUU_Cfam_GSD_1.0
LOC101967812
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505837,312,058 - 37,338,599 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364743,128,053 - 3,163,381 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CTRC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl674,674,836 - 74,681,309 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1674,674,836 - 74,681,311 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2669,055,983 - 69,062,605 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225977
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120116,825,105 - 116,837,192 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605420,553,635 - 20,562,172 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026198   ⟹   ENSHGLP00000025968
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247641,741,703 - 1,747,712 (+)Ensembl
RefSeq Acc Id: XM_004850327   ⟹   XP_004850384
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247641,741,703 - 1,747,715 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850384 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11988 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025968
  ENSHGLP00100020894
GenBank Protein JAN96038 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004850384   ⟸   XM_004850327
- UniProtKB: G5BRS6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025968   ⟸   ENSHGLT00000026198


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018486 Ensembl, ENTREZGENE
  ENSHGLG00100015404 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000026198 ENTREZGENE
  ENSHGLT00100021116 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
InterPro Peptidase_S1_Elastase_sf UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
KEGG Report hgl:101703734 UniProtKB/TrEMBL
NCBI Gene Ctrc ENTREZGENE
PANTHER CHYMOTRYPSIN-C UniProtKB/TrEMBL
  CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER UniProtKB/TrEMBL
Pfam Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
UniProt G5BRS6 ENTREZGENE, UniProtKB/TrEMBL