Tox4 (TOX high mobility group box family member 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tox4 (TOX high mobility group box family member 4) Heterocephalus glaber
Analyze
Symbol: Tox4
Name: TOX high mobility group box family member 4
RGD ID: 18916616
Description: ENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); cone-rod dystrophy 13 (ortholog); purine nucleoside phosphorylase deficiency (ortholog); FOUND IN chromatin (inferred); chromosome, telomeric region (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,493,953 - 7,511,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,493,911 - 7,511,852 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tox4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248257,493,953 - 7,511,846 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248257,493,911 - 7,511,852 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TOX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381421,477,195 - 21,499,170 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1421,476,597 - 21,499,175 (+)EnsemblGRCh38hg38GRCh38
GRCh371421,945,354 - 21,967,314 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361421,015,175 - 21,037,159 (+)NCBINCBI36Build 36hg18NCBI36
Build 341421,015,245 - 21,036,880NCBI
Celera141,810,716 - 1,830,660 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef142,064,581 - 2,085,176 (+)NCBIHuRef
CHM1_11421,946,806 - 21,968,784 (+)NCBICHM1_1
T2T-CHM13v2.01415,674,564 - 15,696,534 (+)NCBIT2T-CHM13v2.0
Tox4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,516,603 - 52,532,966 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1452,516,603 - 52,533,858 (+)EnsemblGRCm39 Ensembl
GRCm381452,279,146 - 52,295,509 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1452,279,146 - 52,296,401 (+)EnsemblGRCm38mm10GRCm38
MGSCv371452,898,821 - 52,915,184 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361451,201,595 - 51,216,463 (+)NCBIMGSCv36mm8
Celera1449,261,686 - 49,277,476 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1426.88NCBI
Tox4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,462,735 - 27,476,320 (+)NCBIGRCr8
mRatBN7.21524,989,246 - 25,002,833 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,988,853 - 25,002,833 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1527,761,942 - 27,775,492 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,716,039 - 28,729,621 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,968,978 - 26,982,572 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,696,378 - 28,709,960 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,695,912 - 28,709,957 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,506,578 - 32,520,161 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,729,485 - 27,743,620 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11527,745,184 - 27,759,317 (+)NCBI
Celera1525,293,401 - 25,306,983 (+)NCBICelera
Cytogenetic Map15p14NCBI
Tox4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555502,195,710 - 2,209,729 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555502,195,710 - 2,209,729 (+)NCBIChiLan1.0ChiLan1.0
TOX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,932,579 - 22,952,483 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11422,149,066 - 22,168,973 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0142,294,892 - 2,316,901 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11420,371,820 - 20,393,696 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1420,371,820 - 20,393,696 (+)Ensemblpanpan1.1panPan2
TOX4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,512,270 - 18,528,293 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,512,327 - 18,528,516 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,996,794 - 19,012,736 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01518,771,256 - 18,787,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,771,289 - 18,788,953 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11518,453,331 - 18,469,249 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01518,509,388 - 18,525,329 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,638,257 - 18,654,205 (+)NCBIUU_Cfam_GSD_1.0
Tox4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,718,872 - 32,737,761 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936880627,576 - 646,006 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936880628,316 - 646,006 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl777,678,475 - 77,698,917 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1777,679,405 - 77,698,952 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,021,649 - 83,040,735 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TOX4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,946,311 - 21,966,197 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,945,901 - 21,965,740 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605924,462,325 - 24,484,109 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000006341   ⟹   ENSHGLP00000006262
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248257,493,953 - 7,511,846 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000006342   ⟹   ENSHGLP00000006263
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248257,494,143 - 7,511,457 (+)Ensembl
RefSeq Acc Id: XM_004865050   ⟹   XP_004865107
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248257,493,911 - 7,511,852 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004865107 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000006262
  ENSHGLP00000006263
  ENSHGLP00100001179
GenBank Protein JAO03540 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004865107   ⟸   XM_004865050
- UniProtKB: A0A0P6K925 (UniProtKB/TrEMBL),   G5BFV0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000006262   ⟸   ENSHGLT00000006341
Ensembl Acc Id: ENSHGLP00000006263   ⟸   ENSHGLT00000006342


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004570 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100000931 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000006341 ENTREZGENE
  ENSHGLT00000006342 UniProtKB/TrEMBL
  ENSHGLT00100001214 UniProtKB/TrEMBL
Gene3D-CATH 1.10.30.10 UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  TOX_HMG-box_domain UniProtKB/TrEMBL
KEGG Report hgl:101700262 UniProtKB/TrEMBL
NCBI Gene Tox4 ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/TrEMBL
  PTHR45781:SF2 UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP SSF47095 UniProtKB/TrEMBL
UniProt A0A0P6K925 ENTREZGENE, UniProtKB/TrEMBL
  G5BFV0 ENTREZGENE, UniProtKB/TrEMBL