Ptprm (protein tyrosine phosphatase receptor type M) - Rat Genome Database

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Gene: Ptprm (protein tyrosine phosphatase receptor type M) Heterocephalus glaber
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Symbol: Ptprm
Name: protein tyrosine phosphatase receptor type M
RGD ID: 18915196
Description: ENCODES a protein that exhibits cadherin binding (ortholog); identical protein binding (ortholog); phosphatase activity (ortholog); INVOLVED IN homophilic cell adhesion via plasma membrane adhesion molecules (ortholog); negative regulation of angiogenesis (ortholog); negative regulation of endothelial cell migration (ortholog); ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); intellectual disability (ortholog); pancreatic ductal adenocarcinoma (ortholog); FOUND IN adherens junction (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor-type tyrosine-protein phosphatase mu
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477016,990,056 - 17,508,167 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477016,900,925 - 17,507,775 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ptprm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477016,990,056 - 17,508,167 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477016,900,925 - 17,507,775 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPRM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38187,567,316 - 8,406,856 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl187,566,782 - 8,406,861 (+)EnsemblGRCh38hg38GRCh38
GRCh37187,567,314 - 8,406,854 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36187,557,314 - 8,396,859 (+)NCBINCBI36Build 36hg18NCBI36
Build 34187,557,816 - 8,396,852NCBI
Celera187,451,391 - 8,291,215 (+)NCBICelera
Cytogenetic Map18p11.23NCBI
HuRef187,531,039 - 8,371,216 (+)NCBIHuRef
CHM1_1187,567,289 - 8,407,034 (+)NCBICHM1_1
T2T-CHM13v2.0187,730,572 - 8,570,006 (+)NCBIT2T-CHM13v2.0
Ptprm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,973,843 - 67,661,486 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,973,942 - 67,661,452 (-)EnsemblGRCm39 Ensembl
GRCm381766,666,848 - 67,354,491 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1766,666,947 - 67,354,457 (-)EnsemblGRCm38mm10GRCm38
MGSCv371767,016,188 - 67,703,799 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361766,572,488 - 67,259,332 (-)NCBIMGSCv36mm8
Celera1770,960,452 - 71,652,526 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1737.88NCBI
Ptprm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89114,086,380 - 114,791,000 (-)NCBIGRCr8
mRatBN7.29106,639,573 - 107,343,698 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9106,639,573 - 107,343,698 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx9115,034,215 - 115,735,168 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09120,156,426 - 120,857,356 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09118,500,097 - 119,201,056 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.09114,846,095 - 115,555,261 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9114,846,095 - 115,555,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09114,341,760 - 115,047,495 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49105,784,922 - 106,503,148 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19106,019,977 - 106,025,031 (-)NCBI
Celera9103,813,416 - 104,503,006 (-)NCBICelera
Cytogenetic Map9q37NCBI
Ptprm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554023,244,222 - 3,756,925 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554023,243,447 - 3,756,457 (-)NCBIChiLan1.0ChiLan1.0
PTPRM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21730,046,539 - 30,873,100 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11815,739,131 - 16,565,623 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,879,556 - 6,706,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1188,205,978 - 9,030,683 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl188,206,677 - 9,030,286 (-)Ensemblpanpan1.1panPan2
PTPRM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1774,005,682 - 74,597,498 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl773,815,186 - 74,609,116 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha773,205,288 - 73,988,613 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0773,864,685 - 74,648,938 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl773,863,785 - 74,660,558 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1773,566,351 - 74,351,414 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0773,596,130 - 74,369,637 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0773,895,451 - 74,674,439 (+)NCBIUU_Cfam_GSD_1.0
Ptprm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494470,374,418 - 71,176,141 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936670890,310 - 1,692,041 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936670890,316 - 1,692,033 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl699,350,303 - 100,092,883 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1699,350,301 - 100,092,966 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2692,516,719 - 92,550,399 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11866,564,562 - 67,398,541 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1866,773,588 - 67,398,542 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605041,491,594 - 42,326,520 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004853219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021265242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01050009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01050017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000011943   ⟹   ENSHGLP00000011814
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477016,990,056 - 17,508,167 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000011944   ⟹   ENSHGLP00000011815
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477016,990,154 - 17,507,012 (+)Ensembl
RefSeq Acc Id: XM_004853219   ⟹   XP_004853276
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,953,520 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265235   ⟹   XP_021120894
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,900,925 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265236   ⟹   XP_021120895
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,900,925 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265237   ⟹   XP_021120896
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,907,743 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265238   ⟹   XP_021120897
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,900,926 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265239   ⟹   XP_021120898
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477017,037,719 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265240   ⟹   XP_021120899
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,900,926 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265241   ⟹   XP_021120900
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,953,520 - 17,507,775 (+)NCBI
RefSeq Acc Id: XM_021265242   ⟹   XP_021120901
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477016,900,927 - 17,507,775 (+)NCBI
RefSeq Acc Id: XP_021120894   ⟸   XM_021265235
- Peptide Label: isoform X1
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120895   ⟸   XM_021265236
- Peptide Label: isoform X2
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120899   ⟸   XM_021265240
- Peptide Label: isoform X6
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120897   ⟸   XM_021265238
- Peptide Label: isoform X4
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120901   ⟸   XM_021265242
- Peptide Label: isoform X9
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120896   ⟸   XM_021265237
- Peptide Label: isoform X3
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120900   ⟸   XM_021265241
- Peptide Label: isoform X7
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853276   ⟸   XM_004853219
- Peptide Label: isoform X8
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120898   ⟸   XM_021265239
- Peptide Label: isoform X5
- UniProtKB: G5C056 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000011815   ⟸   ENSHGLT00000011944
Ensembl Acc Id: ENSHGLP00000011814   ⟸   ENSHGLT00000011943


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008461 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011943 ENTREZGENE
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Immunoglobulins UniProtKB/TrEMBL
  Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  R-PTP-mu_cat_rpt1 UniProtKB/TrEMBL
  R-tyr_protein_phosphatases UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptprm ENTREZGENE
PANTHER PROTEIN TYROSINE PHOSPHATASE, RECEPTOR TYPE, M UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
  Concanavalin A-like lectins/glucanases UniProtKB/TrEMBL
  Fibronectin type III UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
UniProt G5C056 ENTREZGENE, UniProtKB/TrEMBL