Ddhd2 (DDHD domain containing 2) - Rat Genome Database

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Gene: Ddhd2 (DDHD domain containing 2) Heterocephalus glaber
Analyze
Symbol: Ddhd2
Name: DDHD domain containing 2
RGD ID: 18915155
Description: ENCODES a protein that exhibits metal ion binding (inferred); phospholipase activity (inferred); triacylglycerol lipase activity (inferred); INVOLVED IN lipid droplet organization (ortholog); locomotory behavior (ortholog); mitochondrial fission (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia (ortholog); hereditary spastic paraplegia 54 (ortholog); FOUND IN membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phospholipase DDHD2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247805,376,615 - 5,398,221 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247805,374,616 - 5,398,061 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ddhd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247805,376,615 - 5,398,221 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247805,374,616 - 5,398,061 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DDHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38838,231,585 - 38,273,647 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl838,225,218 - 38,275,558 (+)EnsemblGRCh38hg38GRCh38
GRCh37838,089,103 - 38,120,354 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36838,208,264 - 38,238,143 (+)NCBINCBI36Build 36hg18NCBI36
Celera837,041,566 - 37,073,339 (+)NCBICelera
Cytogenetic Map8p11.23NCBI
HuRef836,623,242 - 36,654,349 (+)NCBIHuRef
CHM1_1838,291,006 - 38,322,288 (+)NCBICHM1_1
T2T-CHM13v2.0838,508,534 - 38,550,602 (+)NCBIT2T-CHM13v2.0
Ddhd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39826,215,351 - 26,244,502 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl826,215,373 - 26,244,624 (-)EnsemblGRCm39 Ensembl
GRCm38825,725,324 - 25,754,474 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl825,725,346 - 25,754,596 (-)EnsemblGRCm38mm10GRCm38
MGSCv37826,835,796 - 26,864,752 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36827,189,378 - 27,220,141 (-)NCBIMGSCv36mm8
Celera827,193,610 - 27,222,571 (-)NCBICelera
Cytogenetic Map8A2NCBI
cM Map814.17NCBI
Ddhd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81673,022,136 - 73,051,746 (+)NCBIGRCr8
mRatBN7.21666,319,469 - 66,349,025 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1666,319,466 - 66,349,023 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1671,598,329 - 71,625,576 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01675,004,642 - 75,031,883 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01670,244,534 - 70,271,741 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01671,090,096 - 71,120,713 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,090,045 - 71,118,552 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,751,567 - 70,781,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,694,412 - 70,723,046 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1664,229,544 - 64,256,544 (+)NCBICelera
Cytogenetic Map16q12.4NCBI
Ddhd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546313,836,409 - 13,856,431 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546313,836,401 - 13,856,430 (+)NCBIChiLan1.0ChiLan1.0
DDHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2756,795,159 - 56,826,237 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1832,511,759 - 32,543,293 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0837,533,579 - 37,564,864 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1834,711,446 - 34,741,471 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl834,711,446 - 34,741,471 (+)Ensemblpanpan1.1panPan2
DDHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11627,232,453 - 27,259,071 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1627,234,642 - 27,257,594 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1627,749,775 - 27,776,392 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01629,131,522 - 29,158,127 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1629,108,082 - 29,203,246 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11627,353,865 - 27,380,471 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01627,931,195 - 27,957,832 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01627,970,436 - 27,997,058 (-)NCBIUU_Cfam_GSD_1.0
Ddhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494349,842,339 - 49,867,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367101,593,946 - 1,618,828 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367101,593,899 - 1,616,572 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1548,252,338 - 48,292,181 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11548,239,932 - 48,292,413 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21555,414,923 - 55,455,128 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DDHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1836,246,966 - 36,278,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl836,247,114 - 36,275,899 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660525,712,254 - 5,742,168 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000004943   ⟹   ENSHGLP00000004879
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247805,376,615 - 5,394,104 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000004944   ⟹   ENSHGLP00000004880
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247805,377,134 - 5,397,971 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000004945   ⟹   ENSHGLP00000004881
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247805,377,159 - 5,398,221 (-)Ensembl
RefSeq Acc Id: XM_004855358   ⟹   XP_004855415
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,398,058 (-)NCBI
RefSeq Acc Id: XM_021236799   ⟹   XP_021092458
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,398,059 (-)NCBI
RefSeq Acc Id: XM_021236800   ⟹   XP_021092459
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,398,059 (-)NCBI
RefSeq Acc Id: XM_021236801   ⟹   XP_021092460
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,397,606 (-)NCBI
RefSeq Acc Id: XM_021236802   ⟹   XP_021092461
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,397,588 (-)NCBI
RefSeq Acc Id: XM_021236803   ⟹   XP_021092462
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,397,815 (-)NCBI
RefSeq Acc Id: XM_021236804   ⟹   XP_021092463
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,397,680 (-)NCBI
RefSeq Acc Id: XM_021236805   ⟹   XP_021092464
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,397,035 (-)NCBI
RefSeq Acc Id: XM_021236806   ⟹   XP_021092465
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,374,616 - 5,398,060 (-)NCBI
RefSeq Acc Id: XM_021236807   ⟹   XP_021092466
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,389,929 - 5,398,061 (-)NCBI
RefSeq Acc Id: XR_002386351
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247805,381,057 - 5,398,059 (-)NCBI
RefSeq Acc Id: XP_021092465   ⟸   XM_021236806
- Peptide Label: isoform X4
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092459   ⟸   XM_021236800
- Peptide Label: isoform X2
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092458   ⟸   XM_021236799
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855415   ⟸   XM_004855358
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J375 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092462   ⟸   XM_021236803
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092463   ⟸   XM_021236804
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092460   ⟸   XM_021236801
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092461   ⟸   XM_021236802
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092464   ⟸   XM_021236805
- Peptide Label: isoform X1
- UniProtKB: G5B0A7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092466   ⟸   XM_021236807
- Peptide Label: isoform X5
Ensembl Acc Id: ENSHGLP00000004880   ⟸   ENSHGLT00000004944
Ensembl Acc Id: ENSHGLP00000004881   ⟸   ENSHGLT00000004945
Ensembl Acc Id: ENSHGLP00000004879   ⟸   ENSHGLT00000004943


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003583 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100015588 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000004944 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100021392 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
InterPro DDHD_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
NCBI Gene Ddhd2 ENTREZGENE
PANTHER PA-PL1 PHOSPHOLIPASE FAMILY UniProtKB/TrEMBL
  PHOSPHOLIPASE DDHD2 UniProtKB/TrEMBL
Pfam DDHD UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
PROSITE DDHD UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
SMART DDHD UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
UniProt A0A0P6J375 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PN55_HETGA UniProtKB/TrEMBL
  A0AAX6R6F6_HETGA UniProtKB/TrEMBL
  A0AAX6R7W1_HETGA UniProtKB/TrEMBL
  A0AAX6R8H4_HETGA UniProtKB/TrEMBL
  A0AAX6R991_HETGA UniProtKB/TrEMBL
  G5B0A7 ENTREZGENE, UniProtKB/TrEMBL