Serpini1 (serpin family I member 1) - Rat Genome Database

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Gene: Serpini1 (serpin family I member 1) Heterocephalus glaber
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Symbol: Serpini1
Name: serpin family I member 1
RGD ID: 18913565
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity (ortholog); INVOLVED IN positive regulation of neuron projection development (ortholog); ASSOCIATED WITH cerebral cavernous malformation (ortholog); cerebral cavernous malformation 3 (ortholog); familial encephalopathy with neuroserpin inclusion bodies (ortholog); FOUND IN cytoplasmic vesicle lumen (inferred); extracellular space (inferred); neuronal cell body (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Neuroserpin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473045,739,911 - 45,795,570 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473045,698,714 - 45,791,744 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Serpini1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473045,739,911 - 45,795,570 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473045,698,714 - 45,791,744 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SERPINI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383167,735,721 - 167,825,569 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3167,735,243 - 167,825,569 (+)EnsemblGRCh38hg38GRCh38
GRCh373167,453,509 - 167,543,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363168,936,217 - 169,026,048 (+)NCBINCBI36Build 36hg18NCBI36
Build 343168,936,224 - 169,026,056NCBI
Celera3165,851,868 - 165,941,800 (+)NCBICelera
Cytogenetic Map3q26.1NCBI
HuRef3164,823,494 - 164,913,496 (+)NCBIHuRef
CHM1_13167,416,304 - 167,506,237 (+)NCBICHM1_1
T2T-CHM13v2.03170,519,576 - 170,609,466 (+)NCBIT2T-CHM13v2.0
Serpini1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39375,464,800 - 75,549,830 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl375,464,854 - 75,550,802 (+)EnsemblGRCm39 Ensembl
GRCm38375,557,493 - 75,642,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl375,557,547 - 75,643,495 (+)EnsemblGRCm38mm10GRCm38
MGSCv37375,361,455 - 75,446,445 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36375,643,500 - 75,728,281 (+)NCBIMGSCv36mm8
Celera375,622,674 - 75,707,678 (+)NCBICelera
Cytogenetic Map3E3NCBI
cM Map333.76NCBI
Serpini1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82162,645,209 - 162,731,737 (+)NCBIGRCr8
mRatBN7.22160,346,403 - 160,433,135 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2160,346,758 - 160,433,135 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2167,519,261 - 167,605,550 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02165,523,542 - 165,609,838 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02160,156,334 - 160,242,616 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02174,013,058 - 174,111,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2174,013,288 - 174,111,752 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02193,348,764 - 193,446,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42166,445,765 - 166,555,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12166,395,870 - 166,505,138 (+)NCBI
Celera2154,541,696 - 154,627,933 (+)NCBICelera
Cytogenetic Map2q32NCBI
Serpini1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544816,947,403 - 16,984,130 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544816,947,375 - 16,982,114 (+)NCBIChiLan1.0ChiLan1.0
SERPINI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22165,635,710 - 165,725,485 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13165,640,437 - 165,730,210 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03164,755,803 - 164,845,572 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13172,812,348 - 172,902,372 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3172,865,891 - 172,902,372 (+)Ensemblpanpan1.1panPan2
SERPINI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13432,553,876 - 32,624,708 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3432,553,902 - 32,624,526 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3441,634,867 - 41,710,496 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03432,632,851 - 32,708,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3432,633,267 - 32,708,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13432,577,993 - 32,648,768 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03432,538,519 - 32,614,495 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03432,810,135 - 32,886,159 (+)NCBIUU_Cfam_GSD_1.0
Serpini1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560298,971,772 - 99,053,590 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365934,570,987 - 4,603,130 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365934,569,183 - 4,649,901 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERPINI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13106,559,736 - 106,658,110 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113106,559,326 - 106,636,930 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213115,121,198 - 115,199,343 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERPINI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11521,610,545 - 21,696,611 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1521,610,791 - 21,645,701 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606330,454,469 - 30,541,000 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027606   ⟹   ENSHGLP00000027364
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473045,739,911 - 45,795,570 (+)Ensembl
RefSeq Acc Id: XM_004834555   ⟹   XP_004834612
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473045,698,714 - 45,791,744 (+)NCBI
RefSeq Acc Id: XM_021253895   ⟹   XP_021109554
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473045,698,714 - 45,791,744 (+)NCBI
RefSeq Acc Id: XM_021253896   ⟹   XP_021109555
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473045,745,698 - 45,791,744 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834612 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109554 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109555 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98255 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027364
  ENSHGLP00100024266
GenBank Protein JAO01654 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021109554   ⟸   XM_021253895
- UniProtKB: G5AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834612   ⟸   XM_004834555
- UniProtKB: G5AMJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109555   ⟸   XM_021253896
- UniProtKB: G5AMJ5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000027364   ⟸   ENSHGLT00000027606


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019457 Ensembl, ENTREZGENE
  ENSHGLG00100017816 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027606 ENTREZGENE
  ENSHGLT00100024513 UniProtKB/TrEMBL
Gene3D-CATH 2.30.39.10 UniProtKB/TrEMBL
  3.30.497.10 UniProtKB/TrEMBL
InterPro Serpin_CS UniProtKB/TrEMBL
  Serpin_dom UniProtKB/TrEMBL
  Serpin_fam UniProtKB/TrEMBL
  Serpin_sf UniProtKB/TrEMBL
  Serpin_sf_1 UniProtKB/TrEMBL
  Serpin_sf_2 UniProtKB/TrEMBL
KEGG Report hgl:101716288 UniProtKB/TrEMBL
NCBI Gene Serpini1 ENTREZGENE
PANTHER NEUROSERPIN UniProtKB/TrEMBL
  PTHR11461 UniProtKB/TrEMBL
Pfam Serpin UniProtKB/TrEMBL
PROSITE SERPIN UniProtKB/TrEMBL
SMART SERPIN UniProtKB/TrEMBL
Superfamily-SCOP SSF56574 UniProtKB/TrEMBL
UniProt G5AMJ5 ENTREZGENE, UniProtKB/TrEMBL