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Gene: Serpini1 (serpin family I member 1) Rattus norvegicus
Symbol: Serpini1
Name: serpin family I member 1
Description: Exhibits serine-type endopeptidase inhibitor activity. Involved in positive regulation of neuron projection development and regulation of cell adhesion. Predicted to localize to the extracellular space; neuronal cell body; and secretory granule lumen. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (serpin family I member 1); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
Also known as: neuroserpin; peptidase inhibitor 12; PI-12; protease inhibitor 17; raPIT5a; serine (or cysteine) peptidase inhibitor, clade I, member 1; serine (or cysteine) proteinase inhibitor clade member 1; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serine protease inhibitor 17; serpin I1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; serpin peptidase inhibitor, clade I, member 1
Homo sapiens (human) : SERPINI1 (serpin family I member 1)  HGNC  Alliance
Mus musculus (house mouse) : Serpini1 (serine (or cysteine) peptidase inhibitor, clade I, member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpini1 (serpin family I member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINI1 (serpin family I member 1)
Canis lupus familiaris (dog) : SERPINI1 (serpin family I member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpini1 (serpin family I member 1)
Sus scrofa (pig) : SERPINI1 (serpin family I member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02174,013,058 - 174,111,693 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2174,013,288 - 174,111,752 (+)Ensembl
Rnor_5.02193,348,764 - 193,446,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42166,445,765 - 166,555,032 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12166,395,870 - 166,505,138 (+)NCBI
Celera2154,541,696 - 154,627,933 (+)NCBICelera
Cytogenetic Map2q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Serpini1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619896
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.