Zfhx2 (zinc finger homeobox 2) - Rat Genome Database

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Gene: Zfhx2 (zinc finger homeobox 2) Heterocephalus glaber
Analyze
Symbol: Zfhx2
Name: zinc finger homeobox 2
RGD ID: 18913484
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN adult behavior (ortholog); regulation of sensory perception of pain (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); Marsili syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger homeobox protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,041,153 - 9,053,975 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,025,569 - 9,057,084 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zfhx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,041,153 - 9,053,975 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,025,569 - 9,057,084 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ZFHX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,520,857 - 23,555,952 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,520,857 - 23,556,192 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,990,066 - 24,020,974 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,059,904 - 23,074,374 (-)NCBINCBI36Build 36hg18NCBI36
Build 341423,059,904 - 23,065,839NCBI
Celera143,852,721 - 3,867,194 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef144,106,427 - 4,137,222 (-)NCBIHuRef
CHM1_11423,988,724 - 24,019,518 (-)NCBICHM1_1
T2T-CHM13v2.01417,721,418 - 17,756,364 (-)NCBIT2T-CHM13v2.0
Zfhx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,297,722 - 55,329,875 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,297,719 - 55,329,781 (-)EnsemblGRCm39 Ensembl
GRCm381455,060,268 - 55,092,381 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,060,262 - 55,092,324 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,680,495 - 55,710,885 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,015,729 - 54,046,119 (-)NCBIMGSCv36mm8
MGSCv361446,151,128 - 46,161,960 (-)NCBIMGSCv36mm8
Celera1452,868,033 - 52,897,945 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.05NCBI
Zfhx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,501,755 - 32,541,720 (-)NCBIGRCr8
mRatBN7.21528,533,155 - 28,565,667 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,533,156 - 28,565,128 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,378,866 - 30,410,837 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,526,058 - 31,558,029 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,768,719 - 29,800,689 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,719,313 - 33,752,665 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,720,701 - 33,752,665 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,605,053 - 37,639,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,166,514 - 33,198,613 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,182,838 - 33,186,707 (-)NCBI
Celera1528,111,183 - 28,143,111 (-)NCBICelera
Cytogenetic Map15p13NCBI
Zfhx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,827,360 - 36,839,783 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,810,188 - 36,843,108 (+)NCBIChiLan1.0ChiLan1.0
ZFHX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,950,152 - 24,985,587 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,166,640 - 24,202,079 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,339,326 - 4,370,756 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,433,148 - 22,463,925 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,433,148 - 22,463,925 (-)Ensemblpanpan1.1panPan2
ZFHX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,750,043 - 3,782,679 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,750,230 - 3,763,829 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,672,306 - 3,704,748 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,857,489 - 3,893,155 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,861,063 - 3,874,083 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,551,883 - 3,583,411 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,613,396 - 3,645,816 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,875,478 - 3,907,901 (-)NCBIUU_Cfam_GSD_1.0
Zfhx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,493,160 - 35,523,823 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722864,735 - 895,848 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722865,197 - 895,848 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZFHX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,552,618 - 75,586,132 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,554,876 - 75,586,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,888,042 - 80,897,326 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZFHX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,891,343 - 23,926,507 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,892,443 - 23,905,767 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605922,492,136 - 22,527,213 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000015006   ⟹   ENSHGLP00000014858
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248209,041,153 - 9,053,975 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000015007   ⟹   ENSHGLP00000014859
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248209,041,153 - 9,053,975 (+)Ensembl
RefSeq Acc Id: XM_004864155   ⟹   XP_004864212
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248209,025,569 - 9,057,084 (+)NCBI
RefSeq Acc Id: XM_021243799   ⟹   XP_021099458
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248209,040,784 - 9,054,958 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004864212 (Get FASTA)   NCBI Sequence Viewer  
  XP_021099458 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000014858
  ENSHGLP00000014859
GenBank Protein JAN98127 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004864212   ⟸   XM_004864155
- Peptide Label: isoform X1
- UniProtKB: A0A0P6K261 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099458   ⟸   XM_021243799
- Peptide Label: isoform X2
- UniProtKB: A0A0P6K261 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000014859   ⟸   ENSHGLT00000015007
RefSeq Acc Id: ENSHGLP00000014858   ⟸   ENSHGLT00000015006


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010610 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000015006 ENTREZGENE
  ENSHGLT00000015007 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Zfhx2 ENTREZGENE
PANTHER PTHR45891:SF1 UniProtKB/TrEMBL
  ZINC FINGER HOMEOBOX PROTEIN UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
  ZnF_U1 UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0P6K261 ENTREZGENE, UniProtKB/TrEMBL