Cst11 (cystatin 11) - Rat Genome Database

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Gene: Cst11 (cystatin 11) Heterocephalus glaber
Analyze
Symbol: Cst11
Name: cystatin 11
RGD ID: 18912746
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (inferred); INVOLVED IN defense response to Gram-negative bacterium (inferred); ASSOCIATED WITH familial hyperinsulinemic hypoglycemia 1 (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); sperm flagellum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cystatin-11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474123,104,474 - 23,106,333 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)
sperm flagellum  (IEA)
sperm head  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cst11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474123,104,474 - 23,106,333 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CST11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382023,450,412 - 23,452,876 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2023,450,403 - 23,452,876 (-)EnsemblGRCh38hg38GRCh38
GRCh372023,431,049 - 23,433,513 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362023,379,041 - 23,381,482 (-)NCBINCBI36Build 36hg18NCBI36
Build 342023,379,040 - 23,381,482NCBI
Celera2023,504,421 - 23,506,862 (-)NCBICelera
Cytogenetic Map20p11.21NCBI
HuRef2023,392,703 - 23,395,144 (-)NCBIHuRef
CHM1_12023,431,037 - 23,433,478 (-)NCBICHM1_1
T2T-CHM13v2.02023,509,944 - 23,512,411 (-)NCBIT2T-CHM13v2.0
Cst11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392148,610,538 - 148,613,417 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2148,610,529 - 148,613,417 (-)EnsemblGRCm39 Ensembl
GRCm382148,768,618 - 148,771,497 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2148,768,609 - 148,771,497 (-)EnsemblGRCm38mm10GRCm38
MGSCv372148,594,354 - 148,597,233 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362148,460,059 - 148,462,938 (-)NCBIMGSCv36mm8
Celera2150,030,906 - 150,034,699 (-)NCBICelera
Cytogenetic Map2G3NCBI
cM Map273.54NCBI
Cst11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83156,664,551 - 156,667,275 (-)NCBIGRCr8
mRatBN7.23136,211,414 - 136,214,138 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3136,211,414 - 136,214,138 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3140,163,405 - 140,165,998 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03148,747,551 - 148,750,144 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03146,437,032 - 146,439,756 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03143,096,056 - 143,098,780 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3143,096,056 - 143,098,780 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03149,504,896 - 149,507,620 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43137,524,412 - 137,527,136 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13137,429,984 - 137,432,709 (-)NCBI
Celera3135,052,841 - 135,055,541 (-)NCBICelera
Cytogenetic Map3q41NCBI
Cst11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541530,445,556 - 30,453,439 (-)NCBIChiLan1.0ChiLan1.0
CST11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22124,317,163 - 24,319,887 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12024,313,996 - 24,316,720 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02023,385,639 - 23,388,363 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12023,736,631 - 23,739,084 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2023,736,631 - 23,739,084 (-)Ensemblpanpan1.1panPan2
CST11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.124181,410 - 184,213 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl24180,692 - 184,323 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha24203,332 - 205,991 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.024573,867 - 576,594 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl24573,905 - 576,594 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.124176,259 - 178,909 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.024275,596 - 278,262 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.024559,406 - 562,092 (+)NCBIUU_Cfam_GSD_1.0
Cst11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640148,695,442 - 148,699,181 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366202,115,924 - 2,119,639 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366202,115,927 - 2,119,683 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CST11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,414,051 - 30,417,127 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,415,161 - 30,416,984 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21734,503,160 - 34,505,987 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CST11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660787,271,760 - 7,274,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004841160   ⟹   XP_004841217
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474123,104,474 - 23,106,333 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841217 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB18844 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013020
RefSeq Acc Id: XP_004841217   ⟸   XM_004841160
- UniProtKB: G5CBD3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009307 ENTREZGENE
Ensembl Transcript ENSHGLT00000013157 ENTREZGENE
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro CST11 UniProtKB/TrEMBL
  Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
KEGG Report hgl:101704052 UniProtKB/TrEMBL
NCBI Gene Cst11 ENTREZGENE
PANTHER CYSTATIN-11 UniProtKB/TrEMBL
  PTHR47886 UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt G5CBD3 ENTREZGENE, UniProtKB/TrEMBL