Pmch (pro-melanin concentrating hormone) - Rat Genome Database

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Gene: Pmch (pro-melanin concentrating hormone) Heterocephalus glaber
Analyze
Symbol: Pmch
Name: pro-melanin concentrating hormone
RGD ID: 18911974
Description: ENCODES a protein that exhibits type 1 melanin-concentrating hormone receptor binding (ortholog); INVOLVED IN drinking behavior (ortholog); feeding behavior (ortholog); lactation (ortholog); ASSOCIATED WITH Insulin Resistance (ortholog); obesity (ortholog); sleeping sickness (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Pro-MCH; pro-MCH preproprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247506,109,284 - 6,111,547 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247506,109,542 - 6,110,834 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pmch
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247506,109,284 - 6,111,547 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247506,109,542 - 6,110,834 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PMCH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812102,196,459 - 102,197,833 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12102,196,459 - 102,197,833 (-)EnsemblGRCh38hg38GRCh38
GRCh3712102,590,237 - 102,591,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612101,114,367 - 101,115,744 (-)NCBINCBI36Build 36hg18NCBI36
Build 3412101,092,705 - 101,094,069NCBI
Celera12102,254,196 - 102,255,573 (-)NCBICelera
Cytogenetic Map12q23.2NCBI
HuRef1299,649,705 - 99,651,082 (-)NCBIHuRef
CHM1_112102,556,902 - 102,558,279 (-)NCBICHM1_1
T2T-CHM13v2.012102,157,595 - 102,158,969 (-)NCBIT2T-CHM13v2.0
Pmch
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391087,926,934 - 87,928,236 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1087,926,934 - 87,928,237 (+)EnsemblGRCm39 Ensembl
GRCm381088,091,072 - 88,092,374 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1088,091,072 - 88,092,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv371087,553,817 - 87,555,119 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361087,520,874 - 87,522,172 (+)NCBIMGSCv36mm8
Celera1090,075,720 - 90,077,022 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1043.7NCBI
Pmch
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8724,399,404 - 24,400,720 (+)NCBIGRCr8
mRatBN7.2722,511,934 - 22,513,250 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl722,511,934 - 22,513,250 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx724,506,585 - 24,507,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0726,669,288 - 26,670,604 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0726,446,310 - 26,447,626 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0728,655,206 - 28,656,522 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl728,654,733 - 28,657,522 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0728,764,993 - 28,766,309 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4724,778,133 - 24,779,449 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1724,798,403 - 24,799,720 (+)NCBI
Celera719,682,044 - 19,683,360 (+)NCBICelera
RH 3.4 Map7118.65RGD
Cytogenetic Map7q13NCBI
Pmch
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540537,356,755 - 37,360,695 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540537,357,468 - 37,360,695 (-)NCBIChiLan1.0ChiLan1.0
PMCH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210110,269,790 - 110,271,177 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112110,266,188 - 110,267,581 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01299,783,925 - 99,785,292 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112103,181,777 - 103,183,197 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12103,181,497 - 103,182,616 (-)Ensemblpanpan1.1panPan2
PMCH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11541,036,428 - 41,037,571 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1541,036,428 - 41,037,553 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1541,404,422 - 41,405,547 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01541,690,821 - 41,691,974 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1541,690,821 - 41,691,946 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11540,958,046 - 40,959,171 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01541,054,180 - 41,055,305 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01541,328,497 - 41,329,622 (-)NCBIUU_Cfam_GSD_1.0
Pmch
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494518,937,096 - 18,938,482 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649211,947,489 - 11,948,896 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649211,947,489 - 11,948,896 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PMCH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl582,018,915 - 82,020,266 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1582,018,915 - 82,020,267 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2585,944,967 - 85,946,320 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PMCH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11197,436,682 - 97,438,345 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037147,566,730 - 147,568,089 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000024282   ⟹   ENSHGLP00000024063
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247506,109,284 - 6,111,547 (+)Ensembl
RefSeq Acc Id: XM_004844845   ⟹   XP_004844902
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247506,109,542 - 6,110,834 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844902 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA98201 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024063
  ENSHGLP00100005106
GenBank Protein JAO03508 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004844902   ⟸   XM_004844845
- UniProtKB: G5AME1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000024063   ⟸   ENSHGLT00000024282


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017152 Ensembl, ENTREZGENE
  ENSHGLG00100003866 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000024282 ENTREZGENE
  ENSHGLT00100005185 UniProtKB/TrEMBL
InterPro Prepro-melanin_conc_hormone UniProtKB/TrEMBL
KEGG Report hgl:101708626 UniProtKB/TrEMBL
NCBI Gene Pmch ENTREZGENE
PANTHER PRO-MCH UniProtKB/TrEMBL
  PTHR12091 UniProtKB/TrEMBL
Pfam Pro-MCH UniProtKB/TrEMBL
PRINTS PROMCHFAMILY UniProtKB/TrEMBL
UniProt G5AME1 ENTREZGENE, UniProtKB/TrEMBL