Crym (crystallin mu) - Rat Genome Database

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Gene: Crym (crystallin mu) Heterocephalus glaber
Analyze
Symbol: Crym
Name: crystallin mu
RGD ID: 18909422
Description: ENCODES a protein that exhibits hormone binding (ortholog); NADP binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial transport (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); response to hormone (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 40 (ortholog); congestive heart failure (ortholog); Deafness (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ketimine reductase mu-crystallin; Mu-crystallin-like protein; thiomorpholine-carboxylate dehydrogenase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,321,396 - 7,337,898 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,321,396 - 7,337,286 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (ISO)
mitochondrion  (ISO)
nucleus  (ISO)

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Crym
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,321,396 - 7,337,898 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,321,396 - 7,337,286 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CRYM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381621,258,521 - 21,303,062 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1621,238,874 - 21,303,083 (-)EnsemblGRCh38hg38GRCh38
GRCh371621,269,842 - 21,314,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,177,343 - 21,221,918 (-)NCBINCBI36Build 36hg18NCBI36
Build 341621,177,339 - 21,197,103NCBI
Celera1620,584,147 - 20,628,708 (-)NCBICelera
Cytogenetic Map16p12.2NCBI
HuRef1619,805,090 - 19,849,646 (-)NCBIHuRef
CHM1_11621,357,178 - 21,401,740 (-)NCBICHM1_1
T2T-CHM13v2.01621,193,814 - 21,238,355 (-)NCBIT2T-CHM13v2.0
Crym
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,785,603 - 119,801,212 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7119,785,603 - 119,801,334 (-)EnsemblGRCm39 Ensembl
GRCm387120,186,380 - 120,201,989 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7120,186,380 - 120,202,111 (-)EnsemblGRCm38mm10GRCm38
MGSCv377127,329,898 - 127,345,502 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367119,977,533 - 119,993,137 (-)NCBIMGSCv36mm8
Celera7120,095,865 - 120,111,506 (-)NCBICelera
Cytogenetic Map7F2NCBI
cM Map764.47NCBI
Crym
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,991,752 - 184,006,923 (-)NCBIGRCr8
mRatBN7.21174,560,423 - 174,575,660 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,560,416 - 174,575,633 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1182,885,255 - 182,900,529 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01190,071,297 - 190,086,579 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,797,872 - 182,813,104 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,944,895 - 189,960,069 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,944,895 - 189,960,073 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,874,283 - 196,889,414 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1172,309,365 - 172,324,553 (-)NCBICelera
Cytogenetic Map1q36NCBI
Crym
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955493443,532 - 460,133 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955493443,956 - 460,041 (-)NCBIChiLan1.0ChiLan1.0
CRYM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21822,429,156 - 22,452,719 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,949,691 - 26,969,565 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,127,351 - 17,147,210 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11621,290,477 - 21,310,446 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1621,290,477 - 21,310,446 (-)Ensemblpanpan1.1panPan2
CRYM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,187,073 - 24,204,304 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,187,121 - 24,204,304 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha625,624,820 - 25,642,042 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0624,338,416 - 24,355,639 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl624,338,281 - 24,355,638 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1624,141,814 - 24,159,037 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0624,035,432 - 24,052,651 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0624,420,520 - 24,437,753 (+)NCBIUU_Cfam_GSD_1.0
Crym
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344118,344,108 - 118,359,948 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365016,441,597 - 6,458,188 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365016,441,968 - 6,457,814 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRYM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl324,815,010 - 24,835,836 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1324,815,010 - 24,835,837 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2325,531,621 - 25,569,585 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CRYM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,388,842 - 19,409,230 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,388,841 - 19,409,199 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606810,470,811 - 10,491,479 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025612   ⟹   ENSHGLP00000025389
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247827,321,396 - 7,337,898 (-)Ensembl
RefSeq Acc Id: XM_004855907   ⟹   XP_004855964
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247827,321,396 - 7,337,286 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004855964 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB13203 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025389
  ENSHGLP00000035460
  ENSHGLP00100036403
GenBank Protein JAN97232 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004855964   ⟸   XM_004855907
- UniProtKB: G5BV92 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025389   ⟸   ENSHGLT00000025612


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018085 Ensembl, ENTREZGENE
  ENSHGLG00000036316 UniProtKB/TrEMBL
  ENSHGLG00100017132 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000025612 ENTREZGENE
  ENSHGLT00000052451 UniProtKB/TrEMBL
  ENSHGLT00100056416 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1780.10 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  ODC_Mu_crystall UniProtKB/TrEMBL
  ODC_N UniProtKB/TrEMBL
KEGG Report hgl:101706899 UniProtKB/TrEMBL
NCBI Gene Crym ENTREZGENE
PANTHER KETIMINE REDUCTASE MU-CRYSTALLIN UniProtKB/TrEMBL
  PTHR13812 UniProtKB/TrEMBL
Pfam OCD_Mu_crystall UniProtKB/TrEMBL
PIRSF CryM UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt G5BV92 ENTREZGENE, UniProtKB/TrEMBL