Nsun2 (NOP2/Sun RNA methyltransferase 2) - Rat Genome Database

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Gene: Nsun2 (NOP2/Sun RNA methyltransferase 2) Heterocephalus glaber
Analyze
Symbol: Nsun2
Name: NOP2/Sun RNA methyltransferase 2
RGD ID: 18906950
Description: ENCODES a protein that exhibits mRNA (cytidine-5-)-methyltransferase activity (ortholog); INVOLVED IN hair follicle maturation (ortholog); in utero embryonic development (ortholog); meiotic cell cycle checkpoint signaling (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autosomal recessive intellectual developmental disorder 5 (ortholog); genetic disease (ortholog); FOUND IN chromatoid body (ortholog); extracellular exosome (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NOP2/Sun RNA methyltransferase family member 2; tRNA (cytosine(34)-C(5))-methyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247514,287,249 - 4,309,438 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247514,288,436 - 4,309,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nsun2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247514,287,249 - 4,309,438 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247514,288,436 - 4,309,172 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NSUN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3856,599,239 - 6,633,044 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl56,599,239 - 6,633,291 (-)EnsemblGRCh38hg38GRCh38
GRCh3756,599,352 - 6,633,157 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3656,652,352 - 6,686,157 (-)NCBINCBI36Build 36hg18NCBI36
Build 3456,652,352 - 6,686,157NCBI
Celera56,626,418 - 6,660,533 (-)NCBICelera
Cytogenetic Map5p15.31NCBI
HuRef56,573,722 - 6,608,099 (-)NCBIHuRef
CHM1_156,599,051 - 6,633,433 (-)NCBICHM1_1
T2T-CHM13v2.056,529,664 - 6,563,719 (-)NCBIT2T-CHM13v2.0
Nsun2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391369,760,135 - 69,783,899 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1369,681,865 - 69,783,899 (+)EnsemblGRCm39 Ensembl
GRCm381369,612,016 - 69,635,780 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1369,533,746 - 69,635,780 (+)EnsemblGRCm38mm10GRCm38
MGSCv371369,750,895 - 69,774,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361370,079,616 - 70,103,029 (+)NCBIMGSCv36mm8
Celera1371,956,753 - 71,980,601 (+)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1335.55NCBI
Nsun2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8135,490,583 - 35,514,839 (-)NCBIGRCr8
mRatBN7.2133,662,139 - 33,685,887 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl133,662,139 - 33,685,862 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx133,491,491 - 33,515,193 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0139,490,097 - 39,513,799 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0133,690,317 - 33,714,040 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0136,295,650 - 36,319,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl136,295,650 - 36,319,966 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0137,692,672 - 37,716,930 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4173,820,859 - 3,844,582 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1173,822,627 - 3,844,539 (-)NCBI
Celera132,266,227 - 32,289,950 (-)NCBICelera
Cytogenetic Map1p11NCBI
Nsun2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555044,338,855 - 4,361,520 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555044,339,044 - 4,360,176 (-)NCBIChiLan1.0ChiLan1.0
NSUN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v246,848,107 - 6,880,920 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan155,001,714 - 5,034,493 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v056,921,073 - 6,953,622 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.156,596,414 - 6,629,121 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl56,596,414 - 6,629,121 (-)Ensemblpanpan1.1panPan2
NSUN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,145,176 - 7,172,761 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,144,586 - 7,172,335 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3411,653,467 - 11,681,035 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0347,053,243 - 7,080,793 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl347,052,661 - 7,080,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1347,100,392 - 7,127,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0347,080,917 - 7,108,473 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0347,295,959 - 7,323,555 (+)NCBIUU_Cfam_GSD_1.0
Nsun2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213240,207,658 - 240,234,194 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936634799,176 - 826,852 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936634798,894 - 825,413 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NSUN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1675,335,047 - 75,367,180 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11675,335,565 - 75,414,659 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21681,695,118 - 81,761,793 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NSUN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.146,279,984 - 6,312,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl46,280,001 - 6,312,569 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606422,406,642 - 22,439,412 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000019475   ⟹   ENSHGLP00000019284
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247514,287,249 - 4,309,438 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000019476   ⟹   ENSHGLP00000019285
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247514,288,975 - 4,309,023 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000019477   ⟹   ENSHGLP00000019286
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247514,288,975 - 4,309,023 (-)Ensembl
RefSeq Acc Id: XM_004845153   ⟹   XP_004845210
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247514,288,436 - 4,309,172 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004845210 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019284
GenBank Protein JAN97027 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004845210   ⟸   XM_004845153
- UniProtKB: A0A0P6J3Q6 (UniProtKB/TrEMBL),   G5BJC2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000019286   ⟸   ENSHGLT00000019477
Ensembl Acc Id: ENSHGLP00000019284   ⟸   ENSHGLT00000019475
Ensembl Acc Id: ENSHGLP00000019285   ⟸   ENSHGLT00000019476


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013825 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019475 ENTREZGENE
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro MeTrfase_RsmB-F_NOP2_cat UniProtKB/TrEMBL
  MeTrfase_RsmB/NOP2 UniProtKB/TrEMBL
  RCMT UniProtKB/TrEMBL
  RCMT_NCL1 UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report hgl:101714363 UniProtKB/TrEMBL
NCBI Gene Nsun2 ENTREZGENE
PANTHER PTHR22808 UniProtKB/TrEMBL
  RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2 UniProtKB/TrEMBL
Pfam Methyltr_RsmB-F UniProtKB/TrEMBL
PRINTS RCMTFAMILY UniProtKB/TrEMBL
  RCMTNCL1 UniProtKB/TrEMBL
PROSITE SAM_MT_RSMB_NOP UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0P6J3Q6 ENTREZGENE, UniProtKB/TrEMBL
  G5BJC2 ENTREZGENE, UniProtKB/TrEMBL