Sfmbt2 (Scm like with four mbt domains 2) - Rat Genome Database

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Gene: Sfmbt2 (Scm like with four mbt domains 2) Heterocephalus glaber
Analyze
Symbol: Sfmbt2
Name: Scm like with four mbt domains 2
RGD ID: 18906225
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of gene expression (ortholog); ASSOCIATED WITH hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN aggresome (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Scm-like with four MBT domains protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247752,151,927 - 2,386,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074  


Genomics

Comparative Map Data
Sfmbt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247752,151,927 - 2,386,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SFMBT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38107,158,624 - 7,411,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl107,158,624 - 7,411,488 (-)EnsemblGRCh38hg38GRCh38
GRCh37107,200,586 - 7,453,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,244,255 - 7,493,456 (-)NCBINCBI36Build 36hg18NCBI36
Celera107,129,950 - 7,379,087 (-)NCBICelera
Cytogenetic Map10p14NCBI
HuRef107,118,749 - 7,371,946 (-)NCBIHuRef
CHM1_1107,200,896 - 7,453,725 (-)NCBICHM1_1
T2T-CHM13v2.0107,158,401 - 7,411,442 (-)NCBIT2T-CHM13v2.0
Sfmbt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,375,251 - 10,600,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl210,375,321 - 10,600,064 (+)EnsemblGRCm39 Ensembl
GRCm38210,370,440 - 10,595,253 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,370,510 - 10,595,253 (+)EnsemblGRCm38mm10GRCm38
MGSCv37210,294,209 - 10,516,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36210,288,288 - 10,513,106 (+)NCBIMGSCv36mm8
Celera210,320,248 - 10,520,053 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map27.81NCBI
Sfmbt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81772,844,037 - 73,038,599 (-)NCBIGRCr8
mRatBN7.21767,934,296 - 68,128,905 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1767,935,904 - 68,128,781 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1771,418,494 - 71,602,270 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01775,247,175 - 75,430,958 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01769,290,282 - 69,474,058 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01771,719,012 - 71,904,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1771,723,620 - 71,897,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,408,697 - 73,595,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,200,904 - 79,378,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11779,211,736 - 79,377,708 (-)NCBI
Celera1767,433,594 - 67,609,582 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Sfmbt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542123,691,648 - 23,913,781 (-)NCBIChiLan1.0ChiLan1.0
SFMBT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2819,700,796 - 19,956,846 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11019,706,119 - 19,962,168 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0107,184,075 - 7,439,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1107,167,086 - 7,419,939 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl107,172,229 - 7,419,939 (-)Ensemblpanpan1.1panPan2
SFMBT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,637,365 - 28,856,505 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,661,058 - 28,853,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,679,327 - 25,894,939 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0229,020,642 - 29,236,786 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,020,664 - 29,235,035 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1226,126,002 - 26,341,347 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0226,968,238 - 27,183,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0227,686,628 - 27,902,777 (+)NCBIUU_Cfam_GSD_1.0
Sfmbt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934431,178,953 - 31,393,192 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364847,344,144 - 7,558,341 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFMBT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1063,877,586 - 64,070,770 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11063,877,033 - 64,070,867 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21070,147,465 - 70,194,176 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFMBT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.197,219,723 - 7,474,928 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl97,226,295 - 7,445,892 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605112,542,461 - 12,865,746 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004854532   ⟹   XP_004854589
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247752,151,927 - 2,386,949 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004854589 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHA99721 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000039387
GenBank Protein JAN99912 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004854589   ⟸   XM_004854532
- UniProtKB: G5ARR1 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000037639 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000089358 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.30.30.140 UniProtKB/TrEMBL
  3.90.1150.190 UniProtKB/TrEMBL
InterPro Mbt UniProtKB/TrEMBL
  MBT_SFMBT2_rpt1 UniProtKB/TrEMBL
  MBT_SFMBT2_rpt3 UniProtKB/TrEMBL
  MBT_SFMBT2_rpt4 UniProtKB/TrEMBL
  PcG_chromatin_remod_factors UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Scm-like-4MBT1/2_SAM UniProtKB/TrEMBL
  SLED UniProtKB/TrEMBL
  SLED_sf UniProtKB/TrEMBL
KEGG Report hgl:101724811 UniProtKB/TrEMBL
NCBI Gene Sfmbt2 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 UniProtKB/TrEMBL
Pfam MBT UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  SLED UniProtKB/TrEMBL
PROSITE MBT UniProtKB/TrEMBL
SMART MBT UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt G5ARR1 ENTREZGENE, UniProtKB/TrEMBL