Sfmbt2 (Scm like with four mbt domains 2) - Rat Genome Database

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Gene: Sfmbt2 (Scm like with four mbt domains 2) Chinchilla lanigera
Analyze
Symbol: Sfmbt2
Name: Scm like with four mbt domains 2
RGD ID: 8809712
Description: ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN negative regulation of gene expression (ortholog); ASSOCIATED WITH genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN aggresome (ortholog); cytosol (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Scm-like with four mbt domains 2; scm-like with four MBT domains protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542123,691,648 - 23,913,781 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Sfmbt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542123,691,648 - 23,913,781 (-)NCBIChiLan1.0ChiLan1.0
SFMBT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38107,158,624 - 7,411,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl107,158,624 - 7,411,488 (-)EnsemblGRCh38hg38GRCh38
GRCh37107,200,586 - 7,453,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36107,244,255 - 7,493,456 (-)NCBINCBI36Build 36hg18NCBI36
Celera107,129,950 - 7,379,087 (-)NCBICelera
Cytogenetic Map10p14NCBI
HuRef107,118,749 - 7,371,946 (-)NCBIHuRef
CHM1_1107,200,896 - 7,453,725 (-)NCBICHM1_1
T2T-CHM13v2.0107,158,401 - 7,411,442 (-)NCBIT2T-CHM13v2.0
Sfmbt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39210,375,251 - 10,600,064 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl210,375,321 - 10,600,064 (+)EnsemblGRCm39 Ensembl
GRCm38210,370,440 - 10,595,253 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl210,370,510 - 10,595,253 (+)EnsemblGRCm38mm10GRCm38
MGSCv37210,294,209 - 10,516,787 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36210,288,288 - 10,513,106 (+)NCBIMGSCv36mm8
Celera210,320,248 - 10,520,053 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map27.81NCBI
Sfmbt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81772,844,037 - 73,038,599 (-)NCBIGRCr8
mRatBN7.21767,934,296 - 68,128,905 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1767,935,904 - 68,128,781 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1771,418,494 - 71,602,270 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01775,247,175 - 75,430,958 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01769,290,282 - 69,474,058 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01771,719,012 - 71,904,303 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1771,723,620 - 71,897,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01773,408,697 - 73,595,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41779,200,904 - 79,378,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11779,211,736 - 79,377,708 (-)NCBI
Celera1767,433,594 - 67,609,582 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
SFMBT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2819,700,796 - 19,956,846 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11019,706,119 - 19,962,168 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0107,184,075 - 7,439,100 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1107,167,086 - 7,419,939 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl107,172,229 - 7,419,939 (-)Ensemblpanpan1.1panPan2
SFMBT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,637,365 - 28,856,505 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,661,058 - 28,853,364 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha225,679,327 - 25,894,939 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0229,020,642 - 29,236,786 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,020,664 - 29,235,035 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1226,126,002 - 26,341,347 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0226,968,238 - 27,183,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0227,686,628 - 27,902,777 (+)NCBIUU_Cfam_GSD_1.0
Sfmbt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934431,178,953 - 31,393,192 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364847,344,144 - 7,558,341 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFMBT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1063,877,586 - 64,070,770 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11063,877,033 - 64,070,867 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21070,147,465 - 70,194,176 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFMBT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.197,219,723 - 7,474,928 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl97,226,295 - 7,445,892 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605112,542,461 - 12,865,746 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sfmbt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247752,151,927 - 2,386,949 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005383870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005383871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513772 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_013513773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01022193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AGCD01022199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDI01384258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005383870   ⟹   XP_005383927
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,910,717 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005383871   ⟹   XP_005383928
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,805,951 - 23,910,719 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513767   ⟹   XP_013369221
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,907,964 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513768   ⟹   XP_013369222
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,911,137 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513769   ⟹   XP_013369223
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,913,781 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513771   ⟹   XP_013369225
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,909,438 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513772   ⟹   XP_013369226
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,906,788 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013513773   ⟹   XP_013369227
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495542123,691,648 - 23,892,565 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005383927   ⟸   XM_005383870
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005383928   ⟸   XM_005383871
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VPZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013369223   ⟸   XM_013513769
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013369222   ⟸   XM_013513768
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013369225   ⟸   XM_013513771
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013369221   ⟸   XM_013513767
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013369226   ⟸   XM_013513772
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013369227   ⟸   XM_013513773
- Peptide Label: isoform X1
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000012960 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000019112 ENTREZGENE
  ENSCLAT00000019112.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
InterPro Mbt UniProtKB/TrEMBL
  MBT_SFMBT2_rpt1 UniProtKB/TrEMBL
NCBI Gene Sfmbt2 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 2 UniProtKB/TrEMBL
Pfam MBT UniProtKB/TrEMBL
PROSITE MBT UniProtKB/TrEMBL
SMART MBT UniProtKB/TrEMBL
Superfamily-SCOP Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A8C2VPZ7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-25 Sfmbt2  Scm like with four mbt domains 2    Scm-like with four mbt domains 2  Symbol and/or name change 5135510 APPROVED