Ddx19b (DEAD-box helicase 19B) - Rat Genome Database

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Gene: Ddx19b (DEAD-box helicase 19B) Heterocephalus glaber
Analyze
Symbol: Ddx19b
Name: DEAD-box helicase 19B
RGD ID: 18905006
Description: ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN poly(A)+ mRNA export from nucleus (inferred); PARTICIPATES IN NXF1-NXT1 export pathway; ASSOCIATED WITH autosomal dominant dyskeratosis congenita 6 (ortholog); Charcot-Marie-Tooth disease type 2 (ortholog); genetic disease (ortholog); FOUND IN nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DDX19B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,569,331 - 12,587,821 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,569,308 - 12,592,168 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ddx19b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474612,569,331 - 12,587,821 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474612,569,308 - 12,592,168 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DDX19B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381670,289,767 - 70,335,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1670,289,663 - 70,335,305 (+)EnsemblGRCh38hg38GRCh38
GRCh371670,323,670 - 70,369,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,890,573 - 68,925,232 (+)NCBINCBI36Build 36hg18NCBI36
Build 341668,890,598 - 68,925,230NCBI
Celera1655,160,454 - 55,195,108 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1656,156,341 - 56,200,270 (+)NCBIHuRef
CHM1_11671,731,134 - 71,775,217 (+)NCBICHM1_1
T2T-CHM13v2.01676,100,775 - 76,146,326 (+)NCBIT2T-CHM13v2.0
Ddx19b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398111,729,818 - 111,758,383 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8111,729,820 - 111,758,383 (-)EnsemblGRCm39 Ensembl
GRCm388111,003,186 - 111,031,751 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8111,003,188 - 111,031,751 (-)EnsemblGRCm38mm10GRCm38
MGSCv378113,527,088 - 113,551,664 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368113,889,863 - 113,914,439 (-)NCBIMGSCv36mm8
Celera8115,227,150 - 115,251,693 (-)NCBICelera
Cytogenetic Map8E1NCBI
cM Map857.88NCBI
Ddx19b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81955,877,567 - 55,910,134 (-)NCBIGRCr8
mRatBN7.21938,968,215 - 38,998,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1938,968,215 - 38,997,259 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1945,772,703 - 45,798,431 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01946,426,046 - 46,451,774 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01948,736,974 - 48,762,706 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01943,217,199 - 43,246,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1943,217,161 - 43,275,287 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01954,067,897 - 54,072,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01954,045,135 - 54,061,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41940,924,875 - 40,947,452 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1938,360,365 - 38,385,589 (-)NCBICelera
Cytogenetic Map19q12NCBI
Ddx19b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554843,120,480 - 3,137,917 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554843,120,480 - 3,137,917 (+)NCBIChiLan1.0ChiLan1.0
LOC100984626
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21883,831,985 - 83,871,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11689,760,567 - 89,806,986 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01654,683,291 - 54,718,133 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11670,131,115 - 70,167,548 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1670,126,833 - 70,167,548 (+)Ensemblpanpan1.1panPan2
DDX19B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1576,314,675 - 76,336,318 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl576,314,725 - 76,364,587 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha576,276,509 - 76,298,134 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0576,751,096 - 76,772,739 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl576,725,513 - 76,802,090 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1576,573,320 - 76,594,990 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0576,396,617 - 76,418,072 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0576,888,426 - 76,910,065 (+)NCBIUU_Cfam_GSD_1.0
DDX19B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl613,325,351 - 13,359,459 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1613,328,241 - 13,358,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2613,239,713 - 13,271,120 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103233156
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1553,438,552 - 53,480,623 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl553,443,037 - 53,481,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604716,225,728 - 16,268,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000014072   ⟹   ENSHGLP00000013929
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474612,569,331 - 12,587,217 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000014073   ⟹   ENSHGLP00000013930
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474612,572,318 - 12,587,821 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000014074   ⟹   ENSHGLP00000013931
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474612,572,458 - 12,587,217 (+)Ensembl
RefSeq Acc Id: XM_004842873   ⟹   XP_004842930
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,572,317 - 12,592,168 (+)NCBI
RefSeq Acc Id: XM_021256709   ⟹   XP_021112368
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,569,308 - 12,592,168 (+)NCBI
RefSeq Acc Id: XM_021256710   ⟹   XP_021112369
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474612,572,329 - 12,592,168 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004842930 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112368 (Get FASTA)   NCBI Sequence Viewer  
  XP_021112369 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB04673 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000013929
  ENSHGLP00000013930
Reference Protein Sequences
RefSeq Acc Id: XP_021112368   ⟸   XM_021256709
- Peptide Label: isoform X1
- UniProtKB: G5B5W2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842930   ⟸   XM_004842873
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JB98 (UniProtKB/TrEMBL),   G5B5W2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021112369   ⟸   XM_021256710
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000013929   ⟸   ENSHGLT00000014072
RefSeq Acc Id: ENSHGLP00000013930   ⟸   ENSHGLT00000014073
RefSeq Acc Id: ENSHGLP00000013931   ⟸   ENSHGLT00000014074


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009955 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000014072 ENTREZGENE
  ENSHGLT00000014073 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  6.10.250.2170 UniProtKB/TrEMBL
InterPro DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  RNA_helicase_DEAD_Q_motif UniProtKB/TrEMBL
KEGG Report hgl:101720257 UniProtKB/TrEMBL
NCBI Gene Ddx19b ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE DBP3 UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DDX19B UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
PROSITE HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
  Q_MOTIF UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0P6JB98 ENTREZGENE, UniProtKB/TrEMBL
  G5B5W2 ENTREZGENE, UniProtKB/TrEMBL