Nkx3-2 (NK3 homeobox 2) - Rat Genome Database

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Gene: Nkx3-2 (NK3 homeobox 2) Heterocephalus glaber
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Symbol: Nkx3-2
Name: NK3 homeobox 2
RGD ID: 18904620
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN animal organ development (ortholog); animal organ formation (ortholog); determination of left/right symmetry (ortholog); ASSOCIATED WITH connective tissue disease (ortholog); genetic disease (ortholog); Spondylo-Megaepiphyseal-Metaphyseal Dysplasia (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Nkx-3.2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475518,070,740 - 18,072,883 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475518,070,706 - 18,073,847 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nkx3-2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475518,070,740 - 18,072,883 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475518,070,706 - 18,073,847 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NKX3-2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38413,540,830 - 13,547,744 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl413,540,830 - 13,544,508 (-)EnsemblGRCh38hg38GRCh38
GRCh37413,542,454 - 13,546,132 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36413,151,552 - 13,155,212 (-)NCBINCBI36Build 36hg18NCBI36
Build 34413,218,722 - 13,222,307NCBI
Celera414,008,663 - 14,012,323 (-)NCBICelera
Cytogenetic Map4p15.33NCBI
HuRef412,880,106 - 12,883,766 (-)NCBIHuRef
CHM1_1413,541,051 - 13,544,711 (-)NCBICHM1_1
T2T-CHM13v2.0413,520,522 - 13,527,516 (-)NCBIT2T-CHM13v2.0
Nkx3-2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39541,918,826 - 41,921,563 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl541,918,826 - 41,921,844 (-)EnsemblGRCm39 Ensembl
GRCm38541,761,483 - 41,764,220 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl541,761,483 - 41,764,501 (-)EnsemblGRCm38mm10GRCm38
MGSCv37542,152,722 - 42,155,459 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36542,049,696 - 42,052,468 (-)NCBIMGSCv36mm8
Celera539,220,946 - 39,223,683 (-)NCBICelera
Cytogenetic Map5B3NCBI
cM Map522.58NCBI
Nkx3-2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81473,396,198 - 73,398,585 (+)NCBIGRCr8
mRatBN7.21469,183,795 - 69,186,182 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1469,183,820 - 69,186,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1473,637,752 - 73,640,139 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01474,874,057 - 74,876,444 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01471,332,485 - 71,334,872 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01473,813,531 - 73,818,489 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1473,813,528 - 73,815,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01473,825,360 - 73,828,802 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1468,115,963 - 68,118,823 (+)NCBICelera
Cytogenetic Map14q21NCBI
Nkx3-2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495548010,213,761 - 10,216,860 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495548010,212,929 - 10,215,814 (+)NCBIChiLan1.0ChiLan1.0
NKX3-2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2313,794,967 - 13,801,569 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1413,996,015 - 13,999,693 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v047,958,218 - 7,961,844 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1413,258,949 - 13,262,458 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl413,258,949 - 13,262,458 (-)Ensemblpanpan1.1panPan2
NKX3-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1366,543,046 - 66,546,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl366,543,046 - 66,545,580 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha369,066,358 - 69,070,091 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0367,147,048 - 67,150,794 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl367,147,020 - 67,149,587 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1366,524,627 - 66,528,359 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0366,717,740 - 66,721,472 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0367,087,659 - 67,091,382 (+)NCBIUU_Cfam_GSD_1.0
Nkx3-2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528560,297,353 - 60,300,979 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647713,999,045 - 14,001,659 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647713,999,045 - 14,001,659 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NKX3-2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl89,179,232 - 9,182,892 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.189,179,061 - 9,183,340 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.288,716,507 - 8,720,758 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NKX3-2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12736,641,837 - 36,647,917 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2736,641,932 - 36,644,353 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604783,389,830 - 83,393,630 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004847270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01035933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000026989   ⟹   ENSHGLP00000026751
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475518,070,740 - 18,072,883 (+)Ensembl
RefSeq Acc Id: XM_004847270   ⟹   XP_004847327
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475518,070,706 - 18,073,847 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004847327 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026751
RefSeq Acc Id: XP_004847327   ⟸   XM_004847270
Ensembl Acc Id: ENSHGLP00000026751   ⟸   ENSHGLT00000026989


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019028 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026989 ENTREZGENE
NCBI Gene Nkx3-2 ENTREZGENE