Pa2g4 (proliferation-associated 2G4) - Rat Genome Database

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Gene: Pa2g4 (proliferation-associated 2G4) Heterocephalus glaber
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Symbol: Pa2g4
Name: proliferation-associated 2G4
RGD ID: 18903822
Description: ENCODES a protein that exhibits nucleic acid binding (ortholog); transcription corepressor activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN negative regulation of apoptotic process (ortholog); negative regulation of DNA-templated transcription (ortholog); positive regulation of cell differentiation (ortholog); ASSOCIATED WITH Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proliferation-associated protein 2G4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,896,285 - 11,904,756 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,896,285 - 11,904,989 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleolus  (ISO)
nucleus  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
Pa2g4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,896,285 - 11,904,756 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,896,285 - 11,904,989 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PA2G4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,104,559 - 56,113,910 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,104,537 - 56,113,910 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,498,343 - 56,507,694 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,784,370 - 54,793,961 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,784,691 - 54,793,353NCBI
Celera1256,150,290 - 56,159,843 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,537,242 - 53,546,835 (+)NCBIHuRef
CHM1_11256,465,468 - 56,475,059 (+)NCBICHM1_1
T2T-CHM13v2.01256,072,163 - 56,081,516 (+)NCBIT2T-CHM13v2.0
Pa2g4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,393,635 - 128,401,803 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,393,635 - 128,401,856 (-)EnsemblGRCm39 Ensembl
GRCm3810128,557,766 - 128,565,934 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,557,766 - 128,565,987 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,994,822 - 128,002,990 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,961,592 - 127,968,897 (-)NCBIMGSCv36mm8
Celera10130,949,754 - 130,957,922 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1077.09NCBI
Pa2g4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,569,326 - 1,576,794 (-)NCBIGRCr8
mRatBN7.27984,795 - 992,264 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7983,971 - 992,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,746,905 - 3,754,373 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,622,896 - 5,630,363 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,920,502 - 5,927,971 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,979,587 - 2,987,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,979,588 - 2,987,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,952,383 - 2,960,679 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,846,628 - 1,854,096 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,846,628 - 1,854,096 (-)NCBI
Celera7855,183 - 862,626 (-)NCBICelera
Cytogenetic Map7q11NCBI
Pa2g4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,705,704 - 3,717,403 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,705,704 - 3,715,782 (+)NCBIChiLan1.0ChiLan1.0
PA2G4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,218,516 - 38,227,001 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,214,527 - 38,224,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,801,085 - 32,810,441 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,051,672 - 33,061,262 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,051,672 - 33,061,262 (-)Ensemblpanpan1.1panPan2
PA2G4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110426,074 - 437,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10426,069 - 434,767 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10487,811 - 499,123 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010432,937 - 444,249 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10432,930 - 441,669 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110410,400 - 421,711 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010653,296 - 664,836 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010777,521 - 788,835 (+)NCBIUU_Cfam_GSD_1.0
Pa2g4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,345,893 - 58,353,962 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646516,265 - 524,481 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646516,273 - 523,572 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PA2G4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1521,495,997 - 21,503,297 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,103,723 - 23,106,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PA2G4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,044,845 - 52,054,545 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037193,930,133 - 193,940,436 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000016849   ⟹   ENSHGLP00000016678
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462480211,896,285 - 11,904,756 (-)Ensembl
RefSeq Acc Id: XM_004861396   ⟹   XP_004861453
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462480211,896,285 - 11,904,989 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004861453 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016678
GenBank Protein JAN96257 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004861453   ⟸   XM_004861396
Ensembl Acc Id: ENSHGLP00000016678   ⟸   ENSHGLT00000016849


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011936 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016849 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  3.90.230.10 UniProtKB/TrEMBL
InterPro Creatinase/aminopeptidase-like UniProtKB/TrEMBL
  PA2G4 UniProtKB/TrEMBL
  PA2G4/ARX1 UniProtKB/TrEMBL
  Pept_M24 UniProtKB/TrEMBL
  Pept_M24A_MAP2_BS UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Pa2g4 ENTREZGENE
PANTHER PROLIFERATION-ASSOCIATED PROTEIN 2G4 UniProtKB/TrEMBL
  PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P UniProtKB/TrEMBL
Pfam Peptidase_M24 UniProtKB/TrEMBL
PROSITE MAP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF55920 UniProtKB/TrEMBL
UniProt A0A0P6IWD2_HETGA UniProtKB/TrEMBL