Fndc5 (fibronectin type III domain containing 5) - Rat Genome Database

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Gene: Fndc5 (fibronectin type III domain containing 5) Heterocephalus glaber
Analyze
Symbol: Fndc5
Name: fibronectin type III domain containing 5
RGD ID: 18903119
Description: INVOLVED IN response to muscle activity (ortholog); ASSOCIATED WITH Cardiomegaly (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); endomyocardial fibrosis (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibronectin type III domain-containing protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476415,970,991 - 15,976,682 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fndc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476415,970,991 - 15,976,682 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
FNDC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38132,862,268 - 32,872,484 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl132,862,268 - 32,872,482 (-)EnsemblGRCh38hg38GRCh38
GRCh37133,327,869 - 33,338,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,100,464 - 33,108,934 (-)NCBINCBI36Build 36hg18NCBI36
Build 34132,996,969 - 33,005,440NCBI
Celera131,596,509 - 31,606,718 (-)NCBICelera
Cytogenetic Map1p35.1NCBI
HuRef131,443,482 - 31,467,074 (-)NCBIHuRef
CHM1_1133,443,265 - 33,453,515 (-)NCBICHM1_1
T2T-CHM13v2.0132,722,061 - 32,732,277 (-)NCBIT2T-CHM13v2.0
Fndc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,030,672 - 129,038,386 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,030,477 - 129,038,386 (+)EnsemblGRCm39 Ensembl
GRCm384129,136,870 - 129,144,593 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,136,999 - 129,144,593 (+)EnsemblGRCm38mm10GRCm38
MGSCv374128,814,304 - 128,821,837 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364128,639,364 - 128,646,897 (+)NCBIMGSCv36mm8
Celera4127,477,236 - 127,484,769 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map462.93NCBI
Fndc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85146,765,951 - 146,775,611 (+)NCBIGRCr8
mRatBN7.25141,481,593 - 141,491,257 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5141,481,590 - 141,490,731 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5144,181,715 - 144,188,750 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05145,951,536 - 145,958,571 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05145,951,004 - 145,958,030 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05147,323,240 - 147,330,266 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5147,323,240 - 147,330,266 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,057,680 - 151,064,707 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45148,296,328 - 148,304,372 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15148,308,143 - 148,312,519 (+)NCBI
Celera5139,965,061 - 139,970,393 (+)NCBICelera
Cytogenetic Map5q36NCBI
Fndc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545211,120,823 - 11,126,877 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545211,120,823 - 11,127,010 (-)NCBIChiLan1.0ChiLan1.0
FNDC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21193,951,370 - 193,959,995 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11193,073,575 - 193,082,199 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0132,152,828 - 32,161,447 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1133,338,886 - 33,347,278 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl133,338,886 - 33,347,284 (-)Ensemblpanpan1.1panPan2
FNDC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1268,485,941 - 68,493,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl268,485,935 - 68,492,606 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha265,065,786 - 65,073,356 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,051,020 - 69,058,589 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl269,050,613 - 69,057,703 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1265,862,540 - 65,870,105 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,884,983 - 66,892,545 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0267,876,900 - 67,884,468 (+)NCBIUU_Cfam_GSD_1.0
Fndc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505849,940,375 - 49,951,702 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647415,768,518 - 15,783,999 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647415,765,169 - 15,776,452 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNDC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl689,163,378 - 89,171,795 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1689,163,363 - 89,171,871 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2683,190,623 - 83,197,348 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FNDC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12099,997,627 - 100,007,819 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603316,684,569 - 16,693,140 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000017616   ⟹   ENSHGLP00000017442
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476415,970,991 - 15,976,682 (-)Ensembl
RefSeq Acc Id: XM_004850883   ⟹   XP_004850940
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBI
RefSeq Acc Id: XM_004850884   ⟹   XP_004850941
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBI
RefSeq Acc Id: XM_004850885   ⟹   XP_004850942
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBI
RefSeq Acc Id: XM_021263278   ⟹   XP_021118937
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476415,969,640 - 15,976,683 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004850940 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850941 (Get FASTA)   NCBI Sequence Viewer  
  XP_004850942 (Get FASTA)   NCBI Sequence Viewer  
  XP_021118937 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017442
RefSeq Acc Id: XP_004850940   ⟸   XM_004850883
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004850941   ⟸   XM_004850884
- Peptide Label: isoform X3
- UniProtKB: G5B5K1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850942   ⟸   XM_004850885
- Peptide Label: isoform X4
- UniProtKB: G5B5K1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118937   ⟸   XM_021263278
- Peptide Label: isoform X2
- UniProtKB: G5B5K1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000017442   ⟸   ENSHGLT00000017616


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012494 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017616 ENTREZGENE
Gene3D-CATH Immunoglobulins UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  FNDC5_C UniProtKB/TrEMBL
  FNDC_type_III UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
NCBI Gene Fndc5 ENTREZGENE
PANTHER FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
Pfam DUF4808 UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP Fibronectin type III UniProtKB/TrEMBL
UniProt G5B5K1 ENTREZGENE, UniProtKB/TrEMBL