Kctd1 (potassium channel tetramerization domain containing 1) - Rat Genome Database

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Gene: Kctd1 (potassium channel tetramerization domain containing 1) Heterocephalus glaber
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Symbol: Kctd1
Name: potassium channel tetramerization domain containing 1
RGD ID: 18902150
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (inferred); protein homooligomerization (inferred); ASSOCIATED WITH chromosome 18q deletion syndrome (ortholog); Familial Cirrhosis (ortholog); intellectual disability (ortholog); FOUND IN centriolar satellite (ortholog); cytosol (ortholog); intercellular bridge (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BTB/POZ domain-containing protein KCTD1; potassium channel tetramerisation domain containing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247705,775,458 - 5,968,699 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247705,775,317 - 5,967,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kctd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247705,775,458 - 5,968,699 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247705,775,317 - 5,967,929 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KCTD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381826,454,910 - 26,657,473 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1826,454,910 - 26,657,401 (-)EnsemblGRCh38hg38GRCh38
GRCh371824,034,874 - 24,237,437 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361822,288,872 - 22,474,306 (-)NCBINCBI36Build 36hg18NCBI36
Celera1820,845,489 - 21,030,918 (-)NCBICelera
Cytogenetic Map18q11.2NCBI
HuRef1820,884,642 - 21,087,047 (-)NCBIHuRef
CHM1_11823,962,322 - 24,164,829 (-)NCBICHM1_1
T2T-CHM13v2.01826,649,034 - 26,851,482 (-)NCBIT2T-CHM13v2.0
Kctd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391815,101,742 - 15,284,503 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1815,101,742 - 15,284,503 (-)EnsemblGRCm39 Ensembl
GRCm381814,968,685 - 15,151,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1814,968,685 - 15,151,446 (-)EnsemblGRCm38mm10GRCm38
MGSCv371815,127,194 - 15,309,955 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361815,111,587 - 15,294,464 (-)NCBIMGSCv36mm8
Celera1815,190,943 - 15,377,226 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map188.28NCBI
Kctd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8186,396,947 - 6,591,026 (-)NCBIGRCr8
mRatBN7.2186,122,390 - 6,316,434 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,122,390 - 6,317,393 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx186,347,923 - 6,443,402 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0187,135,540 - 7,231,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0186,406,120 - 6,501,549 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0186,374,778 - 6,474,990 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl186,374,778 - 6,474,990 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0186,336,572 - 6,433,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,225,049 - 6,324,832 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,225,886 - 6,230,085 (-)NCBI
Celera186,151,583 - 6,246,756 (-)NCBICelera
Cytogenetic Map18p13NCBI
Kctd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540214,474,259 - 14,670,329 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540214,478,702 - 14,573,154 (-)NCBIChiLan1.0ChiLan1.0
KCTD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21743,884,173 - 44,087,280 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11829,576,769 - 29,779,878 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01819,711,846 - 19,914,897 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11823,317,307 - 23,519,195 (-)NCBIpanpan1.1PanPan1.1panPan2
KCTD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1762,119,658 - 62,214,365 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl762,118,600 - 62,213,593 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha761,464,661 - 61,648,487 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0762,079,891 - 62,263,653 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl762,169,268 - 62,263,633 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1761,752,645 - 61,936,218 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0761,854,535 - 61,949,020 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0762,067,915 - 62,251,809 (+)NCBIUU_Cfam_GSD_1.0
Kctd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494458,045,310 - 58,233,851 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365505,581,982 - 5,771,090 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCTD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6111,048,202 - 111,148,703 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16111,048,193 - 111,237,868 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26104,006,793 - 104,192,833 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCTD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11853,933,015 - 54,132,849 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1854,039,500 - 54,133,549 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605028,660,787 - 28,863,284 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000025868   ⟹   ENSHGLP00000025641
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247705,775,458 - 5,968,699 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000025869   ⟹   ENSHGLP00000025642
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247705,872,242 - 5,968,699 (+)Ensembl
RefSeq Acc Id: XM_004853136   ⟹   XP_004853193
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247705,872,400 - 5,967,929 (+)NCBI
RefSeq Acc Id: XM_013075301   ⟹   XP_012930755
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247705,872,223 - 5,967,929 (+)NCBI
RefSeq Acc Id: XM_013075304   ⟹   XP_012930758
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247705,775,317 - 5,967,929 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004853193 (Get FASTA)   NCBI Sequence Viewer  
  XP_012930755 (Get FASTA)   NCBI Sequence Viewer  
  XP_012930758 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB09534 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025641
  ENSHGLP00000025642
RefSeq Acc Id: XP_012930758   ⟸   XM_013075304
- Peptide Label: isoform X2
- UniProtKB: A0AAX6R1J3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012930755   ⟸   XM_013075301
- Peptide Label: isoform X3
- UniProtKB: A0AAX6R2A2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004853193   ⟸   XM_004853136
- Peptide Label: isoform X1
- UniProtKB: G5BJS3 (UniProtKB/TrEMBL),   A0AAX6PIZ2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025641   ⟸   ENSHGLT00000025868
Ensembl Acc Id: ENSHGLP00000025642   ⟸   ENSHGLT00000025869


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018260 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025868 ENTREZGENE
  ENSHGLT00000025869 ENTREZGENE
Gene3D-CATH Potassium Channel Kv1.1, Chain A UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  BTB_POZ_KCTD1 UniProtKB/TrEMBL
  DUF3504 UniProtKB/TrEMBL
  KCTD1-15-like_C UniProtKB/TrEMBL
  MAVS UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
NCBI Gene Kctd1 ENTREZGENE
PANTHER BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD1 UniProtKB/TrEMBL
  DUF3504 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 UniProtKB/TrEMBL
  POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  DUF3504 UniProtKB/TrEMBL
  KCTD1-15_CTD UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP POZ domain UniProtKB/TrEMBL
UniProt A0AAX6PIZ2 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R1J3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6R2A2 ENTREZGENE, UniProtKB/TrEMBL
  G5BJS3 ENTREZGENE, UniProtKB/TrEMBL