Asxl2 (ASXL transcriptional regulator 2) - Rat Genome Database

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Gene: Asxl2 (ASXL transcriptional regulator 2) Heterocephalus glaber
Analyze
Symbol: Asxl2
Name: ASXL transcriptional regulator 2 (Ensembl:dystrobrevin beta)
RGD ID: 18899982
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); metal ion binding (inferred); INVOLVED IN adult heart development (ortholog); bone mineralization involved in bone maturation (ortholog); embryonic skeletal system morphogenesis (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); autism spectrum disorder (ortholog); Developmental Disease (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: additional sex combs like 2, transcriptional regulator; putative Polycomb group protein ASXL2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247387,603,252 - 8,100,369 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247387,958,610 - 8,100,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Asxl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247387,603,252 - 8,100,369 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247387,958,610 - 8,100,223 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ASXL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38225,733,753 - 25,878,487 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl225,733,753 - 25,878,487 (-)EnsemblGRCh38hg38GRCh38
GRCh37225,956,622 - 26,101,356 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36225,815,757 - 25,954,816 (-)NCBINCBI36Build 36hg18NCBI36
Build 34225,873,909 - 26,013,007NCBI
Celera225,802,588 - 25,941,650 (-)NCBICelera
Cytogenetic Map2p23.3NCBI
HuRef225,699,339 - 25,838,712 (-)NCBIHuRef
CHM1_1225,891,914 - 26,030,899 (-)NCBICHM1_1
T2T-CHM13v2.0225,769,050 - 25,913,813 (-)NCBIT2T-CHM13v2.0
Asxl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39123,476,892 - 3,560,811 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl123,476,857 - 3,556,852 (+)EnsemblGRCm39 Ensembl
GRCm38123,426,857 - 3,510,811 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl123,426,857 - 3,506,852 (+)EnsemblGRCm38mm10GRCm38
MGSCv37123,426,884 - 3,506,849 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36123,426,901 - 3,502,468 (+)NCBIMGSCv36mm8
Celera123,353,949 - 3,434,249 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map121.81NCBI
Asxl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8632,090,497 - 32,234,487 (+)NCBIGRCr8
mRatBN7.2626,425,017 - 26,514,899 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl626,425,954 - 26,507,477 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0627,835,346 - 27,919,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl627,887,797 - 27,915,563 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0637,644,433 - 37,732,264 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4626,400,855 - 26,482,465 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1626,470,864 - 26,484,531 (+)NCBI
Celera625,902,447 - 25,987,120 (+)NCBICelera
Cytogenetic Map6q14NCBI
Asxl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554697,786,154 - 7,923,500 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554697,786,030 - 7,923,739 (-)NCBIChiLan1.0ChiLan1.0
ASXL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212100,638,203 - 100,792,850 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A100,642,167 - 100,796,817 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A25,730,155 - 25,880,089 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A25,824,278 - 25,973,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A25,832,527 - 25,973,659 (-)Ensemblpanpan1.1panPan2
ASXL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11719,914,026 - 20,065,141 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1719,895,568 - 20,044,691 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1719,810,081 - 19,960,956 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01720,235,589 - 20,386,543 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1720,244,106 - 20,366,511 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11719,923,297 - 20,074,379 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01719,932,920 - 20,084,155 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01719,978,936 - 20,130,179 (-)NCBIUU_Cfam_GSD_1.0
Asxl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629264,237,321 - 64,375,709 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364936,463,744 - 6,594,252 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364936,463,771 - 6,602,244 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASXL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3113,044,836 - 113,180,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13113,044,788 - 113,184,809 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23119,991,762 - 120,173,786 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASXL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11481,770,068 - 81,919,200 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604530,233,714 - 30,387,990 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000008449   ⟹   ENSHGLP00000008360
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,603,252 - 7,865,655 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008450   ⟹   ENSHGLP00000008361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,610,064 - 7,865,435 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008451   ⟹   ENSHGLP00000008362
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,610,064 - 7,865,435 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008452   ⟹   ENSHGLP00000008363
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,610,064 - 7,865,435 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008453   ⟹   ENSHGLP00000008364
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,610,064 - 7,647,620 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008454   ⟹   ENSHGLP00000008365
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,612,403 - 7,865,435 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008455   ⟹   ENSHGLP00000008366
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,865,428 - 8,100,369 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008456   ⟹   ENSHGLP00000008367
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,926,169 - 8,100,369 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000008457   ⟹   ENSHGLP00000008368
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247387,968,825 - 8,100,004 (-)Ensembl
RefSeq Acc Id: XM_004839122   ⟹   XP_004839179
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247387,958,610 - 8,100,223 (-)NCBI
RefSeq Acc Id: XM_021253585   ⟹   XP_021109244
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247387,958,610 - 8,100,223 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004839179 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109244 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008366
GenBank Protein JAN99606 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021109244   ⟸   XM_021253585
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JAQ8 (UniProtKB/TrEMBL),   G5CBL1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839179   ⟸   XM_004839122
- Peptide Label: isoform X1
- UniProtKB: G5CBL1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000008360   ⟸   ENSHGLT00000008449
Ensembl Acc Id: ENSHGLP00000008367   ⟸   ENSHGLT00000008456
Ensembl Acc Id: ENSHGLP00000008366   ⟸   ENSHGLT00000008455
Ensembl Acc Id: ENSHGLP00000008368   ⟸   ENSHGLT00000008457
Ensembl Acc Id: ENSHGLP00000008365   ⟸   ENSHGLT00000008454
Ensembl Acc Id: ENSHGLP00000008364   ⟸   ENSHGLT00000008453
Ensembl Acc Id: ENSHGLP00000008363   ⟸   ENSHGLT00000008452
Ensembl Acc Id: ENSHGLP00000008361   ⟸   ENSHGLT00000008450
Ensembl Acc Id: ENSHGLP00000008362   ⟸   ENSHGLT00000008451


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006048 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000008455 ENTREZGENE, UniProtKB/TrEMBL
InterPro ASX-like_PHD UniProtKB/TrEMBL
  ASX/ASX-like UniProtKB/TrEMBL
  ASX_DEUBAD_dom UniProtKB/TrEMBL
  Asxl_HARE-HTH UniProtKB/TrEMBL
  DEUBAD_dom UniProtKB/TrEMBL
NCBI Gene Asxl2 ENTREZGENE
PANTHER PTHR13578 UniProtKB/TrEMBL
  PTHR13578:SF11 UniProtKB/TrEMBL
Pfam ASXH UniProtKB/TrEMBL
  HARE-HTH UniProtKB/TrEMBL
  PHD_3 UniProtKB/TrEMBL
PROSITE DEUBAD UniProtKB/TrEMBL
  HTH_HARE UniProtKB/TrEMBL
UniProt A0A0P6JAQ8 ENTREZGENE, UniProtKB/TrEMBL
  G5CBL1 ENTREZGENE, UniProtKB/TrEMBL