OTOP3 (otopetrin 3) - Rat Genome Database

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Gene: OTOP3 (otopetrin 3) Chlorocebus sabaeus
Analyze
Symbol: OTOP3
Name: otopetrin 3
RGD ID: 18771683
Description: ENCODES a protein that exhibits proton channel activity (inferred); INVOLVED IN proton transmembrane transport (inferred); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: otopetrin-3; proton channel OTOP3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,730,412 - 46,745,104 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,730,972 - 46,745,021 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607717,516,315 - 17,531,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OTOP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,730,412 - 46,745,104 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1646,730,972 - 46,745,021 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607717,516,315 - 17,531,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OTOP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381774,935,802 - 74,949,992 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1774,935,898 - 74,949,992 (+)EnsemblGRCh38hg38GRCh38
GRCh371772,931,897 - 72,946,087 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,443,492 - 70,457,106 (+)NCBINCBI36Build 36hg18NCBI36
Build 341770,443,491 - 70,457,106NCBI
Celera1769,525,122 - 69,538,736 (+)NCBICelera
Cytogenetic Map17q25.1NCBI
HuRef1768,342,265 - 68,356,433 (+)NCBIHuRef
CHM1_11772,996,714 - 73,010,911 (+)NCBICHM1_1
T2T-CHM13v2.01775,827,605 - 75,841,795 (+)NCBIT2T-CHM13v2.0
Otop3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,225,557 - 115,237,753 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11115,225,557 - 115,237,753 (+)EnsemblGRCm39 Ensembl
GRCm3811115,334,731 - 115,346,927 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,334,731 - 115,346,927 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711115,196,048 - 115,208,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611115,150,869 - 115,163,016 (+)NCBIMGSCv36mm8
Celera11127,100,606 - 127,112,806 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1180.84NCBI
Otop3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810101,076,307 - 101,087,704 (+)NCBIGRCr8
mRatBN7.210100,577,346 - 100,588,729 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl10100,577,392 - 100,588,726 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10105,637,549 - 105,648,857 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010105,100,608 - 105,111,926 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010100,498,380 - 100,509,713 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010103,887,045 - 103,898,331 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10103,891,369 - 103,898,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010104,393,465 - 104,404,614 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,412,853 - 105,423,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110105,431,699 - 105,438,014 (+)NCBI
Celera1099,152,946 - 99,164,011 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Otop3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555531,806,313 - 1,817,698 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555531,806,313 - 1,817,515 (+)NCBIChiLan1.0ChiLan1.0
OTOP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21990,971,951 - 90,987,154 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11795,794,959 - 95,810,148 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01768,880,492 - 68,895,449 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11774,437,267 - 74,451,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1774,437,350 - 74,451,832 (+)Ensemblpanpan1.1panPan2
OTOP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.195,505,848 - 5,515,157 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl95,506,350 - 5,513,846 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha96,184,104 - 6,197,277 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.096,176,417 - 6,189,531 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl96,176,917 - 6,189,452 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.196,213,582 - 6,226,662 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.096,323,913 - 6,337,105 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.096,384,354 - 6,397,454 (-)NCBIUU_Cfam_GSD_1.0
Otop3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056026,127,786 - 6,138,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936594273,866 - 283,663 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936594273,866 - 283,663 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTOP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl126,311,696 - 6,322,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1126,311,308 - 6,323,038 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,296,146 - 6,323,574 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Otop3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248014,772,661 - 4,782,681 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248014,772,600 - 4,783,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
30 18 17 17 17 30 18

Sequence


Ensembl Acc Id: ENSCSAT00000002679   ⟹   ENSCSAP00000000976
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl1646,730,972 - 46,745,021 (-)Ensembl
RefSeq Acc Id: XM_008011807   ⟹   XP_008009998
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.11646,730,412 - 46,745,104 (-)NCBI
Vero_WHO_p1.0NW_02366607717,516,315 - 17,531,400 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008009998 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000000976
  ENSCSAP00000000976.1
RefSeq Acc Id: XP_008009998   ⟸   XM_008011807
- UniProtKB: A0A0D9QX87 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000000976   ⟸   ENSCSAT00000002679


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000004647 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000002679.1 UniProtKB/TrEMBL
InterPro Otopetrin UniProtKB/TrEMBL
NCBI Gene OTOP3 ENTREZGENE
PANTHER PROTON CHANNEL OTOP3 UniProtKB/TrEMBL
  PTHR21522 UniProtKB/TrEMBL
Pfam Otopetrin UniProtKB/TrEMBL
UniProt A0A0D9QX87 ENTREZGENE, UniProtKB/TrEMBL